ID A0A1S3Q4A8_SALSA Unreviewed; 1501 AA.
AC A0A1S3Q4A8;
DT 12-APR-2017, integrated into UniProtKB/TrEMBL.
DT 12-APR-2017, sequence version 1.
DT 27-MAR-2024, entry version 32.
DE SubName: Full=Neurexin-1a-like isoform X7 {ECO:0000313|RefSeq:XP_014034813.1};
GN Name=LOC106589402 {ECO:0000313|RefSeq:XP_014034813.1};
OS Salmo salar (Atlantic salmon).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Protacanthopterygii; Salmoniformes;
OC Salmonidae; Salmoninae; Salmo.
OX NCBI_TaxID=8030 {ECO:0000313|Proteomes:UP000087266, ECO:0000313|RefSeq:XP_014034813.1};
RN [1] {ECO:0000313|RefSeq:XP_014034813.1}
RP IDENTIFICATION.
RC TISSUE=Muscle {ECO:0000313|RefSeq:XP_014034813.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004479}; Single-
CC pass type I membrane protein {ECO:0000256|ARBA:ARBA00004479}.
CC -!- SIMILARITY: Belongs to the neurexin family.
CC {ECO:0000256|ARBA:ARBA00010241}.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00076}.
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DR RefSeq; XP_014034813.1; XM_014179338.1.
DR Proteomes; UP000087266; Chromosome ssa28.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0048856; P:anatomical structure development; IEA:UniProt.
DR CDD; cd00054; EGF_CA; 1.
DR CDD; cd00110; LamG; 6.
DR Gene3D; 2.60.120.200; -; 6.
DR Gene3D; 2.10.25.10; Laminin; 2.
DR InterPro; IPR013320; ConA-like_dom_sf.
DR InterPro; IPR000742; EGF-like_dom.
DR InterPro; IPR001791; Laminin_G.
DR InterPro; IPR003585; Neurexin-like.
DR InterPro; IPR027789; Syndecan/Neurexin_dom.
DR PANTHER; PTHR15036:SF49; AXOTACTIN; 1.
DR PANTHER; PTHR15036; PIKACHURIN-LIKE PROTEIN; 1.
DR Pfam; PF00008; EGF; 1.
DR Pfam; PF02210; Laminin_G_2; 6.
DR Pfam; PF01034; Syndecan; 1.
DR SMART; SM00294; 4.1m; 1.
DR SMART; SM00181; EGF; 3.
DR SMART; SM00282; LamG; 6.
DR SUPFAM; SSF49899; Concanavalin A-like lectins/glucanases; 6.
DR PROSITE; PS50026; EGF_3; 3.
DR PROSITE; PS50025; LAM_G_DOMAIN; 6.
PE 3: Inferred from homology;
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157};
KW EGF-like domain {ECO:0000256|PROSITE-ProRule:PRU00076};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000087266};
KW Signal {ECO:0000256|SAM:SignalP};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..33
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 34..1501
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5010193551"
FT TRANSMEM 1428..1448
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 35..213
FT /note="Laminin G"
FT /evidence="ECO:0000259|PROSITE:PS50025"
FT DOMAIN 209..247
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 273..463
FT /note="Laminin G"
FT /evidence="ECO:0000259|PROSITE:PS50025"
FT DOMAIN 470..664
FT /note="Laminin G"
FT /evidence="ECO:0000259|PROSITE:PS50025"
FT DOMAIN 668..705
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 710..883
FT /note="Laminin G"
FT /evidence="ECO:0000259|PROSITE:PS50025"
FT DOMAIN 897..1072
FT /note="Laminin G"
FT /evidence="ECO:0000259|PROSITE:PS50025"
FT DOMAIN 1084..1121
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 1125..1325
FT /note="Laminin G"
FT /evidence="ECO:0000259|PROSITE:PS50025"
FT REGION 1330..1418
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1468..1501
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1330..1381
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1485..1501
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1501 AA; 164265 MW; 7A798293D72258A2 CRC64;
MCLRVCVMAV CVWAAAPLLC VWLCLCSLGG SRGEVLEFGG VSGQWGRFPV WNACCESILS
FSVRTHSEDG LLLYFDDEGF CDFLELLLLR GKLRLRFSIF CAEPAEVSSG VAVSDGHWHA
VRVKRDWRNT SLEVDGRMEG WAEVKSKRRD MTVFSHTFMG GVSPELHASP LRLTSPGVRD
HAPFAGWLTE VTVNGSAVVM EGSEGVTVGG DGCGPDHVCQ NGGVCSVVEQ KNVCDCTDTG
YKGNDCSEEH YNPGLAHLMI GDQGKLRARE DYLATFKGSE YFCYDLSPSP IQSSSDEITL
SFKTLQRNGL MLHTGKSADY VNLALKNGAV SLVINLGSGA FEALVEPVNG KFNDNAWHDV
KVTRNLRQHS GIGHAMVTIS VDGILTTTGY TQEDYTMLGS DDFFYVGGSP STADLPGSPV
SNNFMGCLKE VVYKNNDVRL ELSRLAKQGD AKMKVSGMVA FKCESVATLD PVTFDTPESF
VALSKWSAKK AGSISFDFRT TEPNGLMLFS HGKPRQQQRK DPRTPPTLKV DFFAIEMLDG
HLYLLLDMGS GTTKTKAIDR KVNDGEWYHV DFQRDGRSGT ISVNSQRTAY TAPGDSEILD
LDDTLYLGGL PEDRQGLIFP TEVWTALLNY GYVGCVRDLF VDGQSKDIRR LAEVQRAVGV
KPSCSREPPK QCLSNPCQHS ATCREGWNRY VCDCSGTGYL GRACERDATI LSYDGSKFMK
VQLPVAMHTE AEDVSLRFRS QRAYGVLMAT TSRNSADTLR LELDGGRVRL TVNLDCIRIN
CTASKGPETI FAGVGLNDNE WHTVRVVRRG KSLKLTVDDL QPVEGQMAGD HTQLEFHNVE
TGIVTEKRFM PAVPSNFIGH LQGLTLNGMP YIDLCKNGDI DYCELNAVIG YKSIVADPVT
FRSRSSYVTL PTLQAYYSMH LFLQFKTTSP DGLILYNRGD GNDFIVVELV KGYLHYVSDL
GNGAHLIKGN SNSPLNDNHW HNVLISRDTN NLHTVKIDTK VTTQTTMGAK NLDLKGDLYV
GGVAKEMYRD LPKLVHSREG FQGCLATVDL NGRLPDLLAD ALATTGQVER GCEVALMKAD
LQGPSTTCQE DSCSNQGVCL QQWEGFSCDC SMTSFGGPLC NDAGTTYIFG RDGGVIVYTW
PPNERPSTRA DRLALGFSTQ QKHATLLRVD SASGLGDYLQ LQIDKGNIRV VFNVGTDDIN
IEETAKFVND GKYHIVRFTR SGGNATLQLD DLPIIERYPS GNIDNERLAI ARQRIPYRLG
RVVDDWLFDK GRQLTIFNSQ TTVTVGRGKE AGQFQGQMAG LYYNGLKILN MAAEGHAHIR
LEGSTRLVGD MPSSITPQSS AAAGANRSDP AANAGDITTT TATNRKQGGG TTQQSTDDLL
VASAECPSDD EDIDPCDPSS AAHPPLPEVK PFPGTSEVVR ESSSTTGMVV GIVAAAALCI
LILLYAMYKY RNRDEGSYHV DESRNYISNS ATQPNGSTKD KPLGIAKISK NKKNKDKEYY
V
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