ID A0A1S3Q4C0_SALSA Unreviewed; 1482 AA.
AC A0A1S3Q4C0;
DT 12-APR-2017, integrated into UniProtKB/TrEMBL.
DT 12-APR-2017, sequence version 1.
DT 27-MAR-2024, entry version 32.
DE SubName: Full=Neurexin-1a-like isoform X21 {ECO:0000313|RefSeq:XP_014034828.1};
GN Name=LOC106589402 {ECO:0000313|RefSeq:XP_014034828.1};
OS Salmo salar (Atlantic salmon).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Protacanthopterygii; Salmoniformes;
OC Salmonidae; Salmoninae; Salmo.
OX NCBI_TaxID=8030 {ECO:0000313|Proteomes:UP000087266, ECO:0000313|RefSeq:XP_014034828.1};
RN [1] {ECO:0000313|RefSeq:XP_014034828.1}
RP IDENTIFICATION.
RC TISSUE=Muscle {ECO:0000313|RefSeq:XP_014034828.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004479}; Single-
CC pass type I membrane protein {ECO:0000256|ARBA:ARBA00004479}.
CC -!- SIMILARITY: Belongs to the neurexin family.
CC {ECO:0000256|ARBA:ARBA00010241}.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00076}.
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DR RefSeq; XP_014034828.1; XM_014179353.1.
DR Proteomes; UP000087266; Chromosome ssa28.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0048856; P:anatomical structure development; IEA:UniProt.
DR CDD; cd00054; EGF_CA; 1.
DR CDD; cd00110; LamG; 6.
DR Gene3D; 2.60.120.200; -; 6.
DR Gene3D; 2.10.25.10; Laminin; 2.
DR InterPro; IPR013320; ConA-like_dom_sf.
DR InterPro; IPR000742; EGF-like_dom.
DR InterPro; IPR001791; Laminin_G.
DR InterPro; IPR003585; Neurexin-like.
DR InterPro; IPR027789; Syndecan/Neurexin_dom.
DR PANTHER; PTHR15036:SF49; AXOTACTIN; 1.
DR PANTHER; PTHR15036; PIKACHURIN-LIKE PROTEIN; 1.
DR Pfam; PF00008; EGF; 1.
DR Pfam; PF02210; Laminin_G_2; 6.
DR Pfam; PF01034; Syndecan; 1.
DR SMART; SM00294; 4.1m; 1.
DR SMART; SM00181; EGF; 3.
DR SMART; SM00282; LamG; 6.
DR SUPFAM; SSF49899; Concanavalin A-like lectins/glucanases; 6.
DR PROSITE; PS50026; EGF_3; 3.
DR PROSITE; PS50025; LAM_G_DOMAIN; 6.
PE 3: Inferred from homology;
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157};
KW EGF-like domain {ECO:0000256|PROSITE-ProRule:PRU00076};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000087266};
KW Signal {ECO:0000256|SAM:SignalP};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..33
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 34..1482
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5010335584"
FT TRANSMEM 1409..1429
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 35..213
FT /note="Laminin G"
FT /evidence="ECO:0000259|PROSITE:PS50025"
FT DOMAIN 209..247
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 264..454
FT /note="Laminin G"
FT /evidence="ECO:0000259|PROSITE:PS50025"
FT DOMAIN 461..655
FT /note="Laminin G"
FT /evidence="ECO:0000259|PROSITE:PS50025"
FT DOMAIN 659..696
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 701..874
FT /note="Laminin G"
FT /evidence="ECO:0000259|PROSITE:PS50025"
FT DOMAIN 888..1063
FT /note="Laminin G"
FT /evidence="ECO:0000259|PROSITE:PS50025"
FT DOMAIN 1066..1103
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 1107..1307
FT /note="Laminin G"
FT /evidence="ECO:0000259|PROSITE:PS50025"
FT REGION 1312..1399
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1449..1482
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1312..1363
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1466..1482
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1482 AA; 162129 MW; 47C3B11475D81B53 CRC64;
MCLRVCVMAV CVWAAAPLLC VWLCLCSLGG SRGEVLEFGG VSGQWGRFPV WNACCESILS
FSVRTHSEDG LLLYFDDEGF CDFLELLLLR GKLRLRFSIF CAEPAEVSSG VAVSDGHWHA
VRVKRDWRNT SLEVDGRMEG WAEVKSKRRD MTVFSHTFMG GVSPELHASP LRLTSPGVRD
HAPFAGWLTE VTVNGSAVVM EGSEGVTVGG DGCGPDHVCQ NGGVCSVVEQ KNVCDCTDTG
YKGNDCSEGL AHLMIGDQAR EDYLATFKGS EYFCYDLSPS PIQSSSDEIT LSFKTLQRNG
LMLHTGKSAD YVNLALKNGA VSLVINLGSG AFEALVEPVN GKFNDNAWHD VKVTRNLRQH
SGIGHAMVTI SVDGILTTTG YTQEDYTMLG SDDFFYVGGS PSTADLPGSP VSNNFMGCLK
EVVYKNNDVR LELSRLAKQG DAKMKVSGMV AFKCESVATL DPVTFDTPES FVALSKWSAK
KAGSISFDFR TTEPNGLMLF SHGKPRQQQR KDPRTPPTLK VDFFAIEMLD GHLYLLLDMG
SGTTKTKAID RKVNDGEWYH VDFQRDGRSG TISVNSQRTA YTAPGDSEIL DLDDTLYLGG
LPEDRQGLIF PTEVWTALLN YGYVGCVRDL FVDGQSKDIR RLAEVQRAVG VKPSCSREPP
KQCLSNPCQH SATCREGWNR YVCDCSGTGY LGRACERDAT ILSYDGSKFM KVQLPVAMHT
EAEDVSLRFR SQRAYGVLMA TTSRNSADTL RLELDGGRVR LTVNLDCIRI NCTASKGPET
IFAGVGLNDN EWHTVRVVRR GKSLKLTVDD LQPVEGQMAG DHTQLEFHNV ETGIVTEKRF
MPAVPSNFIG HLQGLTLNGM PYIDLCKNGD IDYCELNAVI GYKSIVADPV TFRSRSSYVT
LPTLQAYYSM HLFLQFKTTS PDGLILYNRG DGNDFIVVEL VKGYLHYVSD LGNGAHLIKG
NSNSPLNDNH WHNVLISRDT NNLHTVKIDT KVTTQTTMGA KNLDLKGDLY VGGVAKEMYR
DLPKLVHSRE GFQGCLATVD LNGRLPDLLA DALATTGQVE RGCEGPSTTC QEDSCSNQGV
CLQQWEGFSC DCSMTSFGGP LCNDAGTTYI FGRDGGVIVY TWPPNERPST RADRLALGFS
TQQKHATLLR VDSASGLGDY LQLQIDKGNI RVVFNVGTDD INIEETAKFV NDGKYHIVRF
TRSGGNATLQ LDDLPIIERY PSGNIDNERL AIARQRIPYR LGRVVDDWLF DKGRQLTIFN
SQTTVTVGRG KEAGQFQGQM AGLYYNGLKI LNMAAEGHAH IRLEGSTRLV GDMPSSITPQ
SSAAAGANRS DPAANAGDIT TTTATNRKQG GGTTQQSTDD LLVASAECPS DDEDIDPCDP
SSAHPPLPEV KPFPGTSEVV RESSSTTGMV VGIVAAAALC ILILLYAMYK YRNRDEGSYH
VDESRNYISN SATQPNGSTK DKPLGIAKIS KNKKNKDKEY YV
//
