ID A0A1S3Q544_SALSA Unreviewed; 496 AA.
AC A0A1S3Q544;
DT 12-APR-2017, integrated into UniProtKB/TrEMBL.
DT 12-APR-2017, sequence version 1.
DT 27-MAR-2024, entry version 24.
DE SubName: Full=Glutamate receptor ionotropic, NMDA 2B-like {ECO:0000313|RefSeq:XP_014034509.1};
GN Name=LOC106589277 {ECO:0000313|RefSeq:XP_014034509.1};
OS Salmo salar (Atlantic salmon).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Protacanthopterygii; Salmoniformes;
OC Salmonidae; Salmoninae; Salmo.
OX NCBI_TaxID=8030 {ECO:0000313|Proteomes:UP000087266, ECO:0000313|RefSeq:XP_014034509.1};
RN [1] {ECO:0000313|RefSeq:XP_014034509.1}
RP IDENTIFICATION.
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR RefSeq; XP_014034509.1; XM_014179034.1.
DR AlphaFoldDB; A0A1S3Q544; -.
DR KEGG; sasa:106589277; -.
DR Proteomes; UP000087266; Chromosome ssa02.
DR GO; GO:0045211; C:postsynaptic membrane; IEA:UniProtKB-KW.
DR GO; GO:0015276; F:ligand-gated monoatomic ion channel activity; IEA:InterPro.
DR Gene3D; 3.40.190.10; Periplasmic binding protein-like II; 2.
DR InterPro; IPR015683; Ionotropic_Glu_rcpt.
DR InterPro; IPR001320; Iontro_rcpt_C.
DR InterPro; IPR018884; NMDAR2_C.
DR InterPro; IPR001638; Solute-binding_3/MltF_N.
DR PANTHER; PTHR18966:SF382; GLUTAMATE RECEPTOR IONOTROPIC, NMDA 2B; 1.
DR PANTHER; PTHR18966; IONOTROPIC GLUTAMATE RECEPTOR; 1.
DR Pfam; PF10565; NMDAR2_C; 2.
DR Pfam; PF00497; SBP_bac_3; 1.
DR SMART; SM00079; PBPe; 1.
DR SUPFAM; SSF53850; Periplasmic binding protein-like II; 1.
PE 4: Predicted;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Ion channel {ECO:0000256|ARBA:ARBA00023286};
KW Ion transport {ECO:0000256|ARBA:ARBA00023286};
KW Ligand-gated ion channel {ECO:0000256|ARBA:ARBA00023286};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Postsynaptic cell membrane {ECO:0000256|ARBA:ARBA00023257};
KW Receptor {ECO:0000256|ARBA:ARBA00023170,
KW ECO:0000313|RefSeq:XP_014034509.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000087266};
KW Signal {ECO:0000256|ARBA:ARBA00022729};
KW Synapse {ECO:0000256|ARBA:ARBA00023018};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT TRANSMEM 168..191
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 7..146
FT /note="Ionotropic glutamate receptor C-terminal"
FT /evidence="ECO:0000259|SMART:SM00079"
FT REGION 286..313
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 472..496
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 474..488
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 496 AA; 54401 MW; DD194BCEF2D9BC06 CRC64;
MIQEEYVDQV SGLSDNKFQK PNAFSPPFRF GTVPNGSTER NIRNNYPEMH QYMTSFHQKN
VDEALASLKG GKLDAFIYDA AVLNYMAGRD EGCKLVTIGS GKVFATTGYG IAIQKDSGWK
RAVDLAILML FGDGEMEELE ALWLTGICHN EKNEVMSSQL DVDNMAGVFY MLGAAMALSL
ITFIAEHAFY WQLRFCFMGY CTGKPGFTFS ISRGIWSCIH GVQIEENKSA MDSPSATMNM
NMNNTHSNIL RLLRTAKDMT AIPGVNGSPH THGALDYGGH HRGGGESPSI YDISEHRRSL
QERKAPPPPY LPEDNMFSDY ISEVERTFGN LPLKDNNLYQ DHYLHHHSGP GPGLALDKVT
QNPFIPTFGD DQCLLHGGKP YYVKMSPQQQ QQPPQHLLNN SRGDFRGSMG VPSYLPASAT
TGVMSNVTPR FPNDLCLGGG LGGPMGNHHG PRLGGNKLLP VRDGGLGLVG QGGQRPFNGS
SNGHVYEKLS SIESDV
//
