ID A0A1S3Q9L2_SALSA Unreviewed; 630 AA.
AC A0A1S3Q9L2;
DT 12-APR-2017, integrated into UniProtKB/TrEMBL.
DT 12-APR-2017, sequence version 1.
DT 27-MAR-2024, entry version 27.
DE SubName: Full=Kelch-like ECH-associated protein 1 {ECO:0000313|RefSeq:XP_014036074.1, ECO:0000313|RefSeq:XP_014036077.1};
GN Name=LOC106590064 {ECO:0000313|RefSeq:XP_014036074.1,
GN ECO:0000313|RefSeq:XP_014036077.1, ECO:0000313|RefSeq:XP_014036083.1,
GN ECO:0000313|RefSeq:XP_014036089.1};
OS Salmo salar (Atlantic salmon).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Protacanthopterygii; Salmoniformes;
OC Salmonidae; Salmoninae; Salmo.
OX NCBI_TaxID=8030 {ECO:0000313|Proteomes:UP000087266, ECO:0000313|RefSeq:XP_014036089.1};
RN [1] {ECO:0000313|RefSeq:XP_014036074.1, ECO:0000313|RefSeq:XP_014036077.1}
RP IDENTIFICATION.
RC TISSUE=Muscle {ECO:0000313|RefSeq:XP_014036074.1,
RC ECO:0000313|RefSeq:XP_014036077.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- PATHWAY: Protein modification; protein ubiquitination.
CC {ECO:0000256|ARBA:ARBA00004906}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
CC Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC -!- SIMILARITY: Belongs to the KEAP1 family.
CC {ECO:0000256|ARBA:ARBA00005288}.
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DR RefSeq; XP_014036074.1; XM_014180599.1.
DR RefSeq; XP_014036077.1; XM_014180602.1.
DR RefSeq; XP_014036083.1; XM_014180608.1.
DR RefSeq; XP_014036089.1; XM_014180614.1.
DR STRING; 8030.ENSSSAP00000001398; -.
DR PaxDb; 8030-ENSSSAP00000001398; -.
DR GeneID; 106590064; -.
DR KEGG; sasa:106590064; -.
DR OMA; PECNEWR; -.
DR OrthoDB; 5472491at2759; -.
DR UniPathway; UPA00143; -.
DR Proteomes; UP000087266; Chromosome ssa02.
DR Bgee; ENSSSAG00000000789; Expressed in mesonephros and 16 other cell types or tissues.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0070887; P:cellular response to chemical stimulus; IEA:UniProt.
DR GO; GO:0016567; P:protein ubiquitination; IEA:UniProtKB-UniPathway.
DR CDD; cd18458; BACK_KLHL19_KEAP1; 1.
DR CDD; cd18248; BTB_POZ_KLHL19_KEAP1; 1.
DR Gene3D; 1.25.40.420; -; 1.
DR Gene3D; 2.120.10.80; Kelch-type beta propeller; 1.
DR InterPro; IPR011705; BACK.
DR InterPro; IPR017096; BTB-kelch_protein.
DR InterPro; IPR000210; BTB/POZ_dom.
DR InterPro; IPR047098; KEAP1_BACK.
DR InterPro; IPR030563; KEAP1_BTB_POZ_dom.
DR InterPro; IPR015915; Kelch-typ_b-propeller.
DR InterPro; IPR006652; Kelch_1.
DR InterPro; IPR011333; SKP1/BTB/POZ_sf.
DR PANTHER; PTHR45632; LD33804P; 1.
DR Pfam; PF07707; BACK; 1.
DR Pfam; PF00651; BTB; 1.
DR Pfam; PF01344; Kelch_1; 6.
DR PIRSF; PIRSF037037; Kelch-like_protein_gigaxonin; 1.
DR SMART; SM00875; BACK; 1.
DR SMART; SM00225; BTB; 1.
DR SMART; SM00612; Kelch; 6.
DR SUPFAM; SSF117281; Kelch motif; 1.
DR SUPFAM; SSF54695; POZ domain; 1.
DR PROSITE; PS50097; BTB; 1.
PE 3: Inferred from homology;
KW Kelch repeat {ECO:0000256|ARBA:ARBA00022441};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000087266};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT DOMAIN 49..121
FT /note="BTB"
FT /evidence="ECO:0000259|PROSITE:PS50097"
SQ SEQUENCE 630 AA; 69469 MW; 4C1CF4EA6B7910D2 CRC64;
MSNECPTECK AVVTPSTRNG HRVFSYTLES HTAAAFAIMN ELRLDGQLCD VTLRVCYNDL
EAVDFVAHKV VLASSSPVFR AMFTNGLKEC GMEVVPIEGI HPRVMGRLIE FAYTASISVG
EKCVIHVMNG AVMYQIDSVV KACCDFLVTQ LDPSNAIGIA SFAEQISCTE LHQKAREYIY
MNFSQVATQE EFFNLSQCQL VTLISRDELN VRCESVVFQA CVAWVRYDRE NRRPYVQALL
QAVRCHSLTP HFLQAQLQSL EWDDQCKDYL AQIFQDLTLH KPTKVISCRT PKVPQLIYTA
GGYFRQSLSY LEAYNPCTGA WLRLADLQVP RSGLAAVVIS GLFYAVGGRN NAPDGNMDSN
TLDCYNPMNN CWLPCAPMSV PRNRIGVGVI DGMIYAVGGS HGCIHHNSVE RYDPDRDQWH
LVAPMLTRRI GVGVAVINRL LYAGGGFDGT HRLSSSECYN PERDEWKSMA AMNTVRSGAG
VCALGNRIYV MGGYDGTNQL NTVERYDVET DTWSFAASMR HRRSALGVTA HHAKIYVLGG
YDGNTFLDSV ECYDPETDTW SEVTRMMSGR SGVGVAVTME PCQKDLAQCL KHERTEVTGG
CEGGSLGCSG TGGDSGSYHN SRHGAFGKGT
//
