ID   A0A1S3QQS8_SALSA        Unreviewed;       916 AA.
AC   A0A1S3QQS8;
DT   12-APR-2017, integrated into UniProtKB/TrEMBL.
DT   12-APR-2017, sequence version 1.
DT   27-MAR-2024, entry version 24.
DE   SubName: Full=Transient receptor potential cation channel subfamily M member 1-like {ECO:0000313|RefSeq:XP_014042415.1};
GN   Name=LOC106595573 {ECO:0000313|RefSeq:XP_014042415.1};
OS   Salmo salar (Atlantic salmon).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Protacanthopterygii; Salmoniformes;
OC   Salmonidae; Salmoninae; Salmo.
OX   NCBI_TaxID=8030 {ECO:0000313|Proteomes:UP000087266, ECO:0000313|RefSeq:XP_014042415.1};
RN   [1] {ECO:0000313|RefSeq:XP_014042415.1}
RP   IDENTIFICATION.
RG   RefSeq;
RL   Submitted (NOV-2023) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC       pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR   RefSeq; XP_014042415.1; XM_014186940.1.
DR   AlphaFoldDB; A0A1S3QQS8; -.
DR   STRING; 8030.ENSSSAP00000013235; -.
DR   KEGG; sasa:106595573; -.
DR   Proteomes; UP000087266; Unplaced.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0005216; F:monoatomic ion channel activity; IEA:InterPro.
DR   GO; GO:0051262; P:protein tetramerization; IEA:InterPro.
DR   Gene3D; 1.20.5.1010; TRPM, tetramerisation domain; 1.
DR   InterPro; IPR005821; Ion_trans_dom.
DR   InterPro; IPR032415; TRPM_tetra.
DR   InterPro; IPR037162; TRPM_tetra_sf.
DR   PANTHER; PTHR13800:SF13; TRANSIENT RECEPTOR POTENTIAL CATION CHANNEL SUBFAMILY M MEMBER 1; 1.
DR   PANTHER; PTHR13800; TRANSIENT RECEPTOR POTENTIAL CATION CHANNEL, SUBFAMILY M, MEMBER 6; 1.
DR   Pfam; PF00520; Ion_trans; 1.
DR   Pfam; PF16519; TRPM_tetra; 1.
PE   4: Predicted;
KW   Ion channel {ECO:0000256|ARBA:ARBA00023303};
KW   Ion transport {ECO:0000256|ARBA:ARBA00023303};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Receptor {ECO:0000313|RefSeq:XP_014042415.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000087266};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00023303}.
FT   TRANSMEM        52..69
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        139..158
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        236..254
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        274..295
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        358..383
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          149..392
FT                   /note="Ion transport"
FT                   /evidence="ECO:0000259|Pfam:PF00520"
FT   DOMAIN          489..543
FT                   /note="TRPM tetramerisation"
FT                   /evidence="ECO:0000259|Pfam:PF16519"
FT   REGION          82..116
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          592..686
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          806..891
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        592..622
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        647..661
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        806..827
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        834..854
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   916 AA;  104225 MW;  9B1437F647F8C9A1 CRC64;
     MKLLTYQLKN WSNSTCLKLA VAAKHRDFIA HTCSQMLLTD MWMGCLRMGK RNGFKVIFGI
     IFPPSILLMD FRLGEEVTYQ APAENEEAKD KDDDNKSSKE VNADAVSRKG DEEESTVKKR
     RVPIGEKIYE FYNTPFTKFW FNTISYLAYL CLYNYIILVK MERWPSLQEW IVISYIITLG
     MEKVRQILMS EPGKLKQKIN VWAEEYWNIT DAAAIFTFLL GLMLRLQNEP LLGIGRVIYC
     VDIIFWYIRV LDIFGVNKYL GPYVMMIGKM MVDMLYFVVI MLVVLMSFGV ARQAILHPDE
     IPTWRLARNI FYMPYWMIYG EVFADSIDLY AMEINPPCGD NMYDEDGKKL PPCIPGAWLT
     PAIMACYLLV ANILLVNLLI AVFNNTFLEV KSVSNQIWKF QRYQLIMKFH DRPLLPPPLI
     IFSHIYIVLK HVCRRCKRRT EGEQDDRDNK GLQLLLNAEE LKALYEFEEQ CVEEYFREKE
     DEEQSSSNER IRVTSERVEN MAMRLEEVNE REHSMKASLQ TVDLRLGQLE EISGRMMNAL
     EKLAGVDHND LVRTHSGVSS VCDPSSLLRH SSINSSDGYS LYRYHLEMGD DTRSEAGDIK
     SPERKGSQRK GSMRKMVERK GSMRETPTLT TASVKEYGAT LDVVGPRERN HSSSSVSVCE
     GAKETPAQRP EAPTEPSPQP SPAASMDAAL EKAGVTMEKI KLEAAISYPL ERGRSLQYQT
     PETHSDCLTS RPRSRSTMVY NPADGGDEGA TWATDVNNPL TGEQETVTSR SPTMGHWAAR
     FEYKVHPCPF GHMPKVSMEK LVPTTTHTKD EAEVKETTAD REPQEPGKSQ PESNQDGGEE
     KQEAEAKDTS EGLLLVAEDR MYPSLRSKSL NTNPRKVKAG GDWAQRTKSA SSVKDLTAMF
     GGTGETETEV ETDRQC
//