ID A0A1S3QXM0_SALSA Unreviewed; 432 AA.
AC A0A1S3QXM0;
DT 12-APR-2017, integrated into UniProtKB/TrEMBL.
DT 12-APR-2017, sequence version 1.
DT 27-MAR-2024, entry version 28.
DE SubName: Full=Iroquois-class homeodomain protein irx-1-like {ECO:0000313|RefSeq:XP_014044174.1};
GN Name=LOC106597521 {ECO:0000313|RefSeq:XP_014044174.1};
OS Salmo salar (Atlantic salmon).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Protacanthopterygii; Salmoniformes;
OC Salmonidae; Salmoninae; Salmo.
OX NCBI_TaxID=8030 {ECO:0000313|Proteomes:UP000087266, ECO:0000313|RefSeq:XP_014044174.1};
RN [1] {ECO:0000313|RefSeq:XP_014044174.1}
RP IDENTIFICATION.
RC TISSUE=Muscle {ECO:0000313|RefSeq:XP_014044174.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123,
CC ECO:0000256|PROSITE-ProRule:PRU00108}.
CC -!- SIMILARITY: Belongs to the TALE/IRO homeobox family.
CC {ECO:0000256|ARBA:ARBA00008446}.
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DR RefSeq; XP_014044174.1; XM_014188699.1.
DR AlphaFoldDB; A0A1S3QXM0; -.
DR STRING; 8030.ENSSSAP00000021445; -.
DR PaxDb; 8030-ENSSSAP00000021445; -.
DR KEGG; sasa:106597521; -.
DR OMA; HIGNEHI; -.
DR Proteomes; UP000087266; Unplaced.
DR Bgee; ENSSSAG00000010557; Expressed in mesonephros and 6 other cell types or tissues.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0000981; F:DNA-binding transcription factor activity, RNA polymerase II-specific; IEA:InterPro.
DR CDD; cd00086; homeodomain; 1.
DR Gene3D; 1.10.10.60; Homeodomain-like; 1.
DR InterPro; IPR009057; Homeobox-like_sf.
DR InterPro; IPR017970; Homeobox_CS.
DR InterPro; IPR001356; Homeobox_dom.
DR InterPro; IPR008422; Homeobox_KN_domain.
DR InterPro; IPR003893; Iroquois_homeo.
DR PANTHER; PTHR11211; IROQUOIS-CLASS HOMEODOMAIN PROTEIN IRX; 1.
DR PANTHER; PTHR11211:SF13; IROQUOIS-CLASS HOMEODOMAIN PROTEIN IRX-1; 1.
DR Pfam; PF05920; Homeobox_KN; 1.
DR SMART; SM00389; HOX; 1.
DR SMART; SM00548; IRO; 1.
DR SUPFAM; SSF46689; Homeodomain-like; 1.
DR PROSITE; PS00027; HOMEOBOX_1; 1.
DR PROSITE; PS50071; HOMEOBOX_2; 1.
PE 3: Inferred from homology;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125, ECO:0000256|PROSITE-
KW ProRule:PRU00108};
KW Homeobox {ECO:0000256|ARBA:ARBA00023155, ECO:0000256|PROSITE-
KW ProRule:PRU00108};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242, ECO:0000256|PROSITE-
KW ProRule:PRU00108}; Reference proteome {ECO:0000313|Proteomes:UP000087266}.
FT DOMAIN 125..178
FT /note="Homeobox"
FT /evidence="ECO:0000259|PROSITE:PS50071"
FT DNA_BIND 127..179
FT /note="Homeobox"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00108"
FT REGION 179..243
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 263..287
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 310..331
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 179..202
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 203..234
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 432 AA; 47745 MW; E8DAF34EF78655FB CRC64;
MSFPQLGYPQ YLSASQAVYG VDRPGVLTPS SRGGSAEIAG NQSAAAAAVT SVLGMYANPY
TAHNYSAFLP YSSADLALFS QMGSQYELKD SPGVHPGSFT AHTSPAFYPY GQFQYGDPAR
PKNATRESTS TLKAWLNEHR KNPYPTKGEK IMLAIITKMT LTQVSTWFAN ARRRLKKENK
VTWGARSKDD EDGNIFGSDN EGDAEKNDDE EEIDLESIDI DKIDDNDGDQ SNEDEDDKPD
GRHRELDSLE KRRAFALQHD AFDKSKNSIS SGKEELSDRN SNTIVVSPDR QGSFQLPVNT
KPKIWSLAET ATSPDSSVKS NSPSGLTGHT PSQMQHPAFL PSHGLYTCQI GKFHNWTNGA
FLGQNSLLNV RSFLGVNQHQ HHNVHLQTQQ QQQQHQASVL VSTGASPQLS PKHIGTHQSE
SYAQCFIYDY IW
//
