ID A0A1S3QYW5_SALSA Unreviewed; 682 AA.
AC A0A1S3QYW5;
DT 12-APR-2017, integrated into UniProtKB/TrEMBL.
DT 12-APR-2017, sequence version 1.
DT 27-MAR-2024, entry version 29.
DE SubName: Full=Homeobox protein SIX4-like {ECO:0000313|RefSeq:XP_014045298.1};
GN Name=LOC106598809 {ECO:0000313|RefSeq:XP_014045298.1};
OS Salmo salar (Atlantic salmon).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Protacanthopterygii; Salmoniformes;
OC Salmonidae; Salmoninae; Salmo.
OX NCBI_TaxID=8030 {ECO:0000313|Proteomes:UP000087266, ECO:0000313|RefSeq:XP_014045298.1};
RN [1] {ECO:0000313|RefSeq:XP_014045298.1}
RP IDENTIFICATION.
RC TISSUE=Muscle {ECO:0000313|RefSeq:XP_014045298.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|PROSITE-ProRule:PRU00108,
CC ECO:0000256|RuleBase:RU000682}.
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DR RefSeq; XP_014045298.1; XM_014189823.1.
DR AlphaFoldDB; A0A1S3QYW5; -.
DR STRING; 8030.ENSSSAP00000000654; -.
DR PaxDb; 8030-ENSSSAP00000000654; -.
DR Ensembl; ENSSSAT00000183520; ENSSSAP00000154259; ENSSSAG00000000414.
DR GeneID; 106598809; -.
DR KEGG; sasa:106598809; -.
DR OMA; MCGEMEA; -.
DR OrthoDB; 5317763at2759; -.
DR Proteomes; UP000087266; Chromosome ssa01.
DR Bgee; ENSSSAG00000000414; Expressed in muscle tissue and 5 other cell types or tissues.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0000981; F:DNA-binding transcription factor activity, RNA polymerase II-specific; IEA:InterPro.
DR CDD; cd00086; homeodomain; 1.
DR Gene3D; 1.10.10.60; Homeodomain-like; 1.
DR InterPro; IPR009057; Homeobox-like_sf.
DR InterPro; IPR017970; Homeobox_CS.
DR InterPro; IPR001356; Homeobox_dom.
DR InterPro; IPR031701; SIX1_SD.
DR PANTHER; PTHR10390; HOMEOBOX PROTEIN SIX; 1.
DR PANTHER; PTHR10390:SF64; HOMEOBOX PROTEIN SIX4.1-RELATED; 1.
DR Pfam; PF00046; Homeodomain; 1.
DR Pfam; PF16878; SIX1_SD; 1.
DR SMART; SM00389; HOX; 1.
DR SUPFAM; SSF46689; Homeodomain-like; 1.
DR PROSITE; PS00027; HOMEOBOX_1; 1.
DR PROSITE; PS50071; HOMEOBOX_2; 1.
PE 4: Predicted;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125, ECO:0000256|PROSITE-
KW ProRule:PRU00108};
KW Homeobox {ECO:0000256|ARBA:ARBA00023155, ECO:0000256|PROSITE-
KW ProRule:PRU00108};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242, ECO:0000256|PROSITE-
KW ProRule:PRU00108}; Reference proteome {ECO:0000313|Proteomes:UP000087266}.
FT DOMAIN 185..236
FT /note="Homeobox"
FT /evidence="ECO:0000259|PROSITE:PS50071"
FT DNA_BIND 187..237
FT /note="Homeobox"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00108"
FT REGION 226..283
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 545..581
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 227..259
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 261..277
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 682 AA; 73248 MW; FB6CF957E2282A4B CRC64;
MSSSSGEVTI SNDIQKENVK TDRRECIKLL ALDTAELSME RTTSNTDAVH SELLVSATSS
LAFSPEQVAC VCEALQQGGN VDRLARFLWS LPQSDLLRGN ESILKAQALV AFHQARYQEL
YSILENHSFS PSNHSSLQDL WYKARYTEAE KARGRPLGAV DKYRLRRKYP LPRTIWDGEE
TVYCFKERSR NALKDLYKQN RYPSPAEKRN LAKITGLSLT QVSNWFKNRR QRDRNPSEAQ
SKSESDGNHS TEDESSKGQE ELSPLPLSNS SDGAMTHGPL PLQTGSLDSG LVIKQIGDIK
MPPGSSSGVL FNGNLVTSNP STVFHNGGSS YLQAPSNILF NGLNLGVQPL AFNPQRLSGG
VLMGGSGVDM QMQAGQEKGL GSSSVDYASY SGCVNGAEVK LEGVYSMAAQ NAGSSVLTFS
SSSGALQLGG YSQVHVHSGI SDGNGASLLN SNVGLPPLQL PSGSSSSALS QGTIQVNNVA
VSSSSEDSYH HQHHQDKLAM APMHPSTVLY SMGNAGQTSI KKEPLEGGGG GGVYSYHHGL
HLDPSGQLSY SSAPLNSEEV PSSQGPTPSS DITMDSSSSL EPEVYTTLTV STPLMAQTDP
NVHHLQSGEY LRGHNPQPVP SSHILGPGMN NNYMSVSESK VDASGDGVNE MVRVMCEEME
PGEEKELAKL QTVQMDEDMA DL
//
