ID A0A1S3R2I7_SALSA Unreviewed; 777 AA.
AC A0A1S3R2I7;
DT 12-APR-2017, integrated into UniProtKB/TrEMBL.
DT 12-APR-2017, sequence version 1.
DT 27-MAR-2024, entry version 31.
DE SubName: Full=Cullin-1 {ECO:0000313|RefSeq:XP_014045938.1, ECO:0000313|RefSeq:XP_014045939.1};
GN Name=LOC106599302 {ECO:0000313|RefSeq:XP_014045938.1,
GN ECO:0000313|RefSeq:XP_014045939.1};
OS Salmo salar (Atlantic salmon).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Protacanthopterygii; Salmoniformes;
OC Salmonidae; Salmoninae; Salmo.
OX NCBI_TaxID=8030 {ECO:0000313|Proteomes:UP000087266, ECO:0000313|RefSeq:XP_014045939.1};
RN [1] {ECO:0000313|RefSeq:XP_014045938.1, ECO:0000313|RefSeq:XP_014045939.1}
RP IDENTIFICATION.
RC TISSUE=Muscle {ECO:0000313|RefSeq:XP_014045938.1,
RC ECO:0000313|RefSeq:XP_014045939.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- PATHWAY: Protein modification; protein ubiquitination.
CC {ECO:0000256|ARBA:ARBA00004906}.
CC -!- SIMILARITY: Belongs to the cullin family.
CC {ECO:0000256|ARBA:ARBA00006019, ECO:0000256|PROSITE-ProRule:PRU00330,
CC ECO:0000256|RuleBase:RU003829}.
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DR RefSeq; XP_014045938.1; XM_014190463.1.
DR RefSeq; XP_014045939.1; XM_014190464.1.
DR STRING; 8030.ENSSSAP00000070871; -.
DR PaxDb; 8030-ENSSSAP00000070871; -.
DR Ensembl; ENSSSAT00000129406; ENSSSAP00000095083; ENSSSAG00000063329.
DR GeneID; 106599302; -.
DR KEGG; sasa:106599302; -.
DR OMA; IREWDRY; -.
DR OrthoDB; 5474206at2759; -.
DR UniPathway; UPA00143; -.
DR Proteomes; UP000087266; Chromosome ssa03.
DR Bgee; ENSSSAG00000063329; Expressed in testis and 14 other cell types or tissues.
DR GO; GO:0031461; C:cullin-RING ubiquitin ligase complex; IEA:InterPro.
DR GO; GO:0031625; F:ubiquitin protein ligase binding; IEA:InterPro.
DR GO; GO:0016567; P:protein ubiquitination; IEA:UniProtKB-UniPathway.
DR GO; GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
DR Gene3D; 1.20.1310.10; Cullin Repeats; 4.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 2.
DR InterPro; IPR045093; Cullin.
DR InterPro; IPR016157; Cullin_CS.
DR InterPro; IPR016158; Cullin_homology.
DR InterPro; IPR036317; Cullin_homology_sf.
DR InterPro; IPR001373; Cullin_N.
DR InterPro; IPR019559; Cullin_neddylation_domain.
DR InterPro; IPR016159; Cullin_repeat-like_dom_sf.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR11932; CULLIN; 1.
DR PANTHER; PTHR11932:SF169; CULLIN-1; 1.
DR Pfam; PF00888; Cullin; 1.
DR Pfam; PF10557; Cullin_Nedd8; 1.
DR SMART; SM00182; CULLIN; 1.
DR SMART; SM00884; Cullin_Nedd8; 1.
DR SUPFAM; SSF75632; Cullin homology domain; 1.
DR SUPFAM; SSF74788; Cullin repeat-like; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS01256; CULLIN_1; 1.
DR PROSITE; PS50069; CULLIN_2; 1.
PE 3: Inferred from homology;
KW Isopeptide bond {ECO:0000256|ARBA:ARBA00022499};
KW Reference proteome {ECO:0000313|Proteomes:UP000087266};
KW Ubl conjugation {ECO:0000256|ARBA:ARBA00022843}.
FT DOMAIN 418..645
FT /note="Cullin family profile"
FT /evidence="ECO:0000259|PROSITE:PS50069"
FT REGION 60..79
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 777 AA; 89977 MW; 2DAE125B2F6CE2C9 CRC64;
MSSNRSQNPH GLKQIGLDQI WDDLRAGIQQ VYTRQSMAKA RYMELYTHVY NYCTSVHQSN
QARGAGPPPS KPSKKAPTPG GAQFVGLELY KRLKEFLKNY LTNLLKDGED LMDESVLKFY
TQQWEDYRFS SKVLNGICAY LNRHWVRREC DEGRKGIYEI YSLALVTWRE CLFRPLNKQV
TNAVLKLIEK ERNGETINTR LISGVVQSYV ELGLNEDDAF AKGPTLSVYK EYFETQFLAD
TERFYTREST EFLQQNPVTE YMKKAEARLL EEQRRVQVYL HESTQDELAR KCEQVLIEKH
LEIFHTEFQN LLDADKNEDL GRMYNLVSRI TDGLGELKKL LETHIYNQGL AAIEKCGEAA
LNDPKMYVQT ILDVHKKYNA LVMSAFNNDA GFVAALDKAC GRFINNNAVT KMVQSSSKSP
ELLARYCDSL LKKSSKNPEE AELEDTLNQV MVVFKYIEDK DVFQKFYAKM LAKRLVHQNS
ASDDAEASMI SKLKQACGFE YTSKLQRMFQ DIGVSKDLNE QFKKHLTNSE PLDLDFSIQV
LSSGSWPFQQ SCTFALPSEL ERSYQRFTAF YASRHSGRKL TWLYHLSKGE LVTNCFKNRY
TLQASTFQMA ILLQYNTEDV YTVQQLTDST QIKIDILVQV LQILLKSKLL VLEDENANVD
EVEFKPDTLI KLFLGYKNKK LRVNINVPMK TEQKQEQETT HKNIEEDRKL LIQAAIVRIM
KMRKVLKHQQ LLAEVLNQLS SRFKPRVPVI KKCIDILIEK EYLERVDGEK DTYSYLA
//
