ID A0A1S3R4L6_SALSA Unreviewed; 495 AA.
AC A0A1S3R4L6;
DT 12-APR-2017, integrated into UniProtKB/TrEMBL.
DT 12-APR-2017, sequence version 1.
DT 27-MAR-2024, entry version 27.
DE SubName: Full=Fizzy-related protein homolog isoform X2 {ECO:0000313|RefSeq:XP_014046790.1, ECO:0000313|RefSeq:XP_014046791.1};
GN Name=LOC106599985 {ECO:0000313|RefSeq:XP_014046790.1,
GN ECO:0000313|RefSeq:XP_014046791.1, ECO:0000313|RefSeq:XP_014046792.1,
GN ECO:0000313|RefSeq:XP_014046794.1};
OS Salmo salar (Atlantic salmon).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Protacanthopterygii; Salmoniformes;
OC Salmonidae; Salmoninae; Salmo.
OX NCBI_TaxID=8030 {ECO:0000313|Proteomes:UP000087266, ECO:0000313|RefSeq:XP_014046792.1};
RN [1] {ECO:0000313|RefSeq:XP_014046790.1, ECO:0000313|RefSeq:XP_014046791.1}
RP IDENTIFICATION.
RC TISSUE=Muscle {ECO:0000313|RefSeq:XP_014046790.1,
RC ECO:0000313|RefSeq:XP_014046791.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the WD repeat CDC20/Fizzy family.
CC {ECO:0000256|ARBA:ARBA00006445}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR RefSeq; XP_014046790.1; XM_014191315.1.
DR RefSeq; XP_014046791.1; XM_014191316.1.
DR RefSeq; XP_014046792.1; XM_014191317.1.
DR RefSeq; XP_014046794.1; XM_014191319.1.
DR STRING; 8030.ENSSSAP00000119832; -.
DR PaxDb; 8030-ENSSSAP00000119832; -.
DR Ensembl; ENSSSAT00000155167; ENSSSAP00000119836; ENSSSAG00000080501.
DR GeneID; 106599985; -.
DR OMA; NAHLSCM; -.
DR OrthoDB; 20041at2759; -.
DR Proteomes; UP000087266; Chromosome ssa03.
DR Bgee; ENSSSAG00000081269; Expressed in semen and 14 other cell types or tissues.
DR GO; GO:0010997; F:anaphase-promoting complex binding; IEA:InterPro.
DR GO; GO:0097027; F:ubiquitin-protein transferase activator activity; IEA:InterPro.
DR CDD; cd00200; WD40; 1.
DR Gene3D; 2.130.10.10; YVTN repeat-like/Quinoprotein amine dehydrogenase; 1.
DR InterPro; IPR024977; Apc4-like_WD40_dom.
DR InterPro; IPR033010; Cdc20/Fizzy.
DR InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR InterPro; IPR019775; WD40_repeat_CS.
DR InterPro; IPR036322; WD40_repeat_dom_sf.
DR InterPro; IPR001680; WD40_rpt.
DR PANTHER; PTHR19918; CELL DIVISION CYCLE 20 CDC20 FIZZY -RELATED; 1.
DR PANTHER; PTHR19918:SF34; FIZZY_CELL DIVISION CYCLE 20 RELATED 1 (DROSOPHILA); 1.
DR Pfam; PF12894; ANAPC4_WD40; 1.
DR Pfam; PF00400; WD40; 3.
DR SMART; SM00320; WD40; 6.
DR SUPFAM; SSF50978; WD40 repeat-like; 1.
DR PROSITE; PS00678; WD_REPEATS_1; 1.
DR PROSITE; PS50082; WD_REPEATS_2; 3.
DR PROSITE; PS50294; WD_REPEATS_REGION; 2.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000087266};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW WD repeat {ECO:0000256|ARBA:ARBA00022574, ECO:0000256|PROSITE-
KW ProRule:PRU00221}.
FT REPEAT 227..268
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT DOMAIN 229..283
FT /note="Anaphase-promoting complex subunit 4-like WD40"
FT /evidence="ECO:0000259|Pfam:PF12894"
FT REPEAT 311..343
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 441..474
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REGION 66..87
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 144..168
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 66..84
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 144..164
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 495 AA; 54701 MW; 5BB0E3114A341304 CRC64;
MDQDYECRLL RQINIQNENA SPIKAIDAVR ALTPTNSPLS SPSKHGDRFI PSRAGANWSV
NFHRINENEK SHNQNRKTKD GTTDTSKADG LAYSALLKNE LLGAGIEKVQ DPQSEDRRLQ
PSTPAKRSLF SYSVCAKRSL PEDGNTVSPY SLSPVSSNSQ KLLRSPRKPT RKISKIPFKV
LDAPELQDDF YLNLVDWSSL NVLSVGLGTC VYLWSACTSQ VTRLCDLSVE GDSVTSVGWS
ERGNLVAVGT HKGYVQIWDA AAGKKLSVLE GHTARVGALA WNADQLSSGS RDRVILQRDI
RAPPLQSERR LQGHRQEVCG LKWSTDHQLL ASGGNDNKLL VWNHSSVVPV QQYTEHLAAV
KAIAWSPHQH GLLASGGGTA DRCIRFWNTL TGQPLQCTDT GSQVCNLAWS KHTNELVSTH
GYSQNQILVW KYPSLTQVAK LTGHSYRVLY LAMSPDGEAI VTGAGDETLR FWNVFSKMRS
TKESVSVLNL FTRIR
//
