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Database: UniProt
Entry: A0A1S3R6A0_SALSA
LinkDB: A0A1S3R6A0_SALSA
Original site: A0A1S3R6A0_SALSA 
ID   A0A1S3R6A0_SALSA        Unreviewed;       422 AA.
AC   A0A1S3R6A0;
DT   12-APR-2017, integrated into UniProtKB/TrEMBL.
DT   12-APR-2017, sequence version 1.
DT   31-JUL-2019, entry version 15.
DE   SubName: Full=ATP-sensitive inward rectifier potassium channel 10-like isoform X4 {ECO:0000313|RefSeq:XP_014047367.1};
GN   Name=LOC106600497 {ECO:0000313|RefSeq:XP_014047367.1};
OS   Salmo salar (Atlantic salmon).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Protacanthopterygii;
OC   Salmoniformes; Salmonidae; Salmoninae; Salmo.
OX   NCBI_TaxID=8030 {ECO:0000313|Proteomes:UP000087266, ECO:0000313|RefSeq:XP_014047367.1};
RN   [1] {ECO:0000313|RefSeq:XP_014047367.1}
RP   IDENTIFICATION.
RC   TISSUE=Muscle {ECO:0000313|RefSeq:XP_014047367.1};
RG   RefSeq;
RL   Submitted (JUN-2017) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|RuleBase:RU003822};
CC       Multi-pass membrane protein {ECO:0000256|RuleBase:RU003822}.
CC   -!- SIMILARITY: Belongs to the inward rectifier-type potassium channel
CC       (TC 1.A.2.1) family. {ECO:0000256|RuleBase:RU003822,
CC       ECO:0000256|SAAS:SAAS00549381}.
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DR   RefSeq; XP_014047367.1; XM_014191892.1.
DR   GeneID; 106600497; -.
DR   OrthoDB; 956263at2759; -.
DR   Proteomes; UP000087266; Genome assembly.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005242; F:inward rectifier potassium channel activity; IEA:InterPro.
DR   GO; GO:0034765; P:regulation of ion transmembrane transport; IEA:UniProtKB-KW.
DR   Gene3D; 2.60.40.1400; -; 1.
DR   InterPro; IPR014756; Ig_E-set.
DR   InterPro; IPR041647; IRK_C.
DR   InterPro; IPR016449; K_chnl_inward-rec_Kir.
DR   InterPro; IPR003269; K_chnl_inward-rec_Kir1.2.
DR   InterPro; IPR013518; K_chnl_inward-rec_Kir_cyto.
DR   InterPro; IPR040445; Kir_TM.
DR   PANTHER; PTHR11767; PTHR11767; 1.
DR   PANTHER; PTHR11767:SF21; PTHR11767:SF21; 1.
DR   Pfam; PF01007; IRK; 1.
DR   Pfam; PF17655; IRK_C; 1.
DR   PIRSF; PIRSF005465; GIRK_kir; 1.
DR   PRINTS; PR01320; KIRCHANNEL.
DR   SUPFAM; SSF81296; SSF81296; 1.
PE   3: Inferred from homology;
KW   Complete proteome {ECO:0000313|Proteomes:UP000087266};
KW   Ion channel {ECO:0000256|RuleBase:RU003822,
KW   ECO:0000256|SAAS:SAAS00434609, ECO:0000313|RefSeq:XP_014047367.1};
KW   Ion transport {ECO:0000256|RuleBase:RU003822,
KW   ECO:0000256|SAAS:SAAS00434639};
KW   Membrane {ECO:0000256|SAAS:SAAS00434581, ECO:0000256|SAM:Phobius};
KW   Potassium {ECO:0000256|RuleBase:RU003822,
KW   ECO:0000256|SAAS:SAAS00434575};
KW   Potassium transport {ECO:0000256|RuleBase:RU003822,
KW   ECO:0000256|SAAS:SAAS00434641};
KW   Reference proteome {ECO:0000313|Proteomes:UP000087266};
KW   Transmembrane {ECO:0000256|RuleBase:RU003822,
KW   ECO:0000256|SAAS:SAAS00434543, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAAS:SAAS00036756,
KW   ECO:0000256|SAM:Phobius};
KW   Transport {ECO:0000256|RuleBase:RU003822,
KW   ECO:0000256|SAAS:SAAS00036755};
KW   Voltage-gated channel {ECO:0000256|RuleBase:RU003822,
KW   ECO:0000256|SAAS:SAAS00048561}.
FT   TRANSMEM     85    106       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    159    184       Helical. {ECO:0000256|SAM:Phobius}.
FT   DOMAIN       49    189       IRK. {ECO:0000259|Pfam:PF01007}.
FT   DOMAIN      196    364       IRK_C. {ECO:0000259|Pfam:PF17655}.
FT   REGION      364    422       Disordered. {ECO:0000256|SAM:MobiDB-
FT                                lite}.
FT   COMPBIAS    388    411       Polyampholyte. {ECO:0000256|SAM:MobiDB-
FT                                lite}.
FT   SITE        175    175       Role in the control of polyamine-mediated
FT                                channel gating and in the blocking by
FT                                intracellular magnesium.
FT                                {ECO:0000256|PIRSR:PIRSR005465-1}.
SQ   SEQUENCE   422 AA;  47129 MW;  80A0B5C6BF6084E2 CRC64;
     MEMEYIRLES CSPQKVCHSQ TQTDVLKPLL GAGGSGGGGT LRRRRRVLSK DGRSNVRIEH
     ISGRSALYMR DLWTTFLDMQ WRWKFFLFTL TFTGTWFLFG VLWYLVALVH GDLLEFNPPS
     NHTPCVLQMQ TLTGAFLFSL ESQTTIGYGF RCITEECPAA IILLILQLVI TMVLEIFITG
     TFLAKVARPK KRGETVKFSQ HAVVSSHEGR PCLMIRVANM RKSLLLGCQV TGKLLQTSHT
     KEGETVRLDQ RNVPFQVDTS SDSPFLILPL TFYHIIDDNS PLRAWAAKGG GWTDPELADF
     ELLVIMSATV EPTSATCQVR TSYLPDEILW GYEFPPVVSL SPSGKYVADF AFFDKVAKTK
     TTPLFKTSRP QSYHGNGGGG GGGVEGTDPE KIRLEQSYRE RGEEGRGRVR DSSPLSVRIS
     NV
//
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