ID   A0A1S3R6P4_SALSA        Unreviewed;      1002 AA.
AC   A0A1S3R6P4;
DT   12-APR-2017, integrated into UniProtKB/TrEMBL.
DT   12-APR-2017, sequence version 1.
DT   27-MAR-2024, entry version 28.
DE   RecName: Full=Oxysterol-binding protein {ECO:0000256|RuleBase:RU003845};
GN   Name=LOC106600847 {ECO:0000313|RefSeq:XP_014048035.1};
OS   Salmo salar (Atlantic salmon).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Protacanthopterygii; Salmoniformes;
OC   Salmonidae; Salmoninae; Salmo.
OX   NCBI_TaxID=8030 {ECO:0000313|Proteomes:UP000087266, ECO:0000313|RefSeq:XP_014048035.1};
RN   [1] {ECO:0000313|RefSeq:XP_014048035.1}
RP   IDENTIFICATION.
RC   TISSUE=Muscle {ECO:0000313|RefSeq:XP_014048035.1};
RG   RefSeq;
RL   Submitted (NOV-2023) to UniProtKB.
CC   -!- SIMILARITY: Belongs to the OSBP family.
CC       {ECO:0000256|RuleBase:RU003844}.
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DR   RefSeq; XP_014048035.1; XM_014192560.1.
DR   AlphaFoldDB; A0A1S3R6P4; -.
DR   STRING; 8030.ENSSSAP00000008389; -.
DR   PaxDb; 8030-ENSSSAP00000008389; -.
DR   Ensembl; ENSSSAT00000008948; ENSSSAP00000008389; ENSSSAG00000004103.
DR   GeneID; 106600847; -.
DR   OrthoDB; 960at2759; -.
DR   Proteomes; UP000087266; Chromosome ssa03.
DR   Bgee; ENSSSAG00000004103; Expressed in ovary and 10 other cell types or tissues.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR   GO; GO:0008289; F:lipid binding; IEA:UniProtKB-KW.
DR   GO; GO:0006869; P:lipid transport; IEA:UniProtKB-KW.
DR   CDD; cd13287; PH_ORP3_ORP6_ORP7; 1.
DR   Gene3D; 2.40.160.120; -; 1.
DR   Gene3D; 3.30.70.3490; -; 1.
DR   Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 1.
DR   InterPro; IPR037239; OSBP_sf.
DR   InterPro; IPR000648; Oxysterol-bd.
DR   InterPro; IPR018494; Oxysterol-bd_CS.
DR   InterPro; IPR011993; PH-like_dom_sf.
DR   InterPro; IPR041680; PH_8.
DR   InterPro; IPR001849; PH_domain.
DR   PANTHER; PTHR10972:SF146; OXYSTEROL-BINDING PROTEIN; 1.
DR   PANTHER; PTHR10972; OXYSTEROL-BINDING PROTEIN-RELATED; 1.
DR   Pfam; PF01237; Oxysterol_BP; 1.
DR   Pfam; PF15409; PH_8; 1.
DR   SMART; SM00233; PH; 1.
DR   SUPFAM; SSF144000; Oxysterol-binding protein-like; 1.
DR   SUPFAM; SSF50729; PH domain-like; 1.
DR   PROSITE; PS01013; OSBP; 1.
DR   PROSITE; PS50003; PH_DOMAIN; 1.
PE   3: Inferred from homology;
KW   Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW   Lipid transport {ECO:0000256|ARBA:ARBA00023055,
KW   ECO:0000256|RuleBase:RU003845};
KW   Lipid-binding {ECO:0000256|ARBA:ARBA00023121};
KW   Reference proteome {ECO:0000313|Proteomes:UP000087266};
KW   Transport {ECO:0000256|ARBA:ARBA00022448, ECO:0000256|RuleBase:RU003845}.
FT   DOMAIN          123..218
FT                   /note="PH"
FT                   /evidence="ECO:0000259|PROSITE:PS50003"
FT   REGION          62..98
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          491..528
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          547..597
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          928..955
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        561..575
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1002 AA;  112761 MW;  3256F19F1B70B206 CRC64;
     MGGRKIKVRL ISRWPRPWVI HGFQSCVSSK REPCRKTELT FSDVVHPIVM MDPRVCPPSL
     NNSQSLMSSL DKSPSGGFKA GHSRNDSAGS SRNSRQNSRH WEVLEDHMDM GSGIGSGLDM
     SIPGICEGFL MKRRKYPLKG WHKRYFLLEK GILKYSKTQQ DIQRGKLHGS LDVSLAVMSI
     NKKSNRIDLD GGDYLYHLKA KNNDLFYIWL TKLCAHRVFK KNEALGVHHG VLHALTMGNS
     TLLPAMASLA QRNQAAMPGM YPHYASSASV YQAEMEVPPT AAPGVNGKVA AWLQQTHQSD
     TCSQELARSQ LDLTELAQLI QRLNWLESGQ QPISNSDLER RINMQNLTLN TPKAKKERKT
     TNKIFGHSRT LSGVEARSMF TSSHLSTSSN HLSVGAASVS SIPDYVYSQL SNPLITSPEA
     KKIQQDICAL SHRVHASLKS IHEVLALERE RVRQAWTGPD LRSSTSNQLA TLCSTLSELE
     VQSCQTKVHS LSLSSGSTGG SKESYSTVRQ DQNAEKTPSK GCSVQRTPSL ADSMAEYYDA
     RDVVCENSSE NGEEESDESG LSDITTTSNS EPDEVHASTL PAEAISPDQP QSKASATLNY
     RTSVSRAPDM VSTVPTNTGR RTVLPANCVD NSHIGIMTIL YNNIGKDLSR VSMPCGLNEP
     LNLLQRVSEE LEYSELLDIA NSTEDPFERM LYIGVFSISG YAWATWRNRY KPFNPVLGET
     YESHRKERGF RYIAEQVSHH PPCSAVHAES ENFTFWQDQQ WKNKFWGKSL EIISSGPVNV
     KLPKYGDHYE WNKVVTCVHN VLSQQRWLEH YGEVTIRNTK SDLCTCKISF VKSRYWTSET
     SKNEVQGQVL NQAGEVVHRF GGLWHEGIFC DTLPNPKCIW KPNPQPDDHF QYYGFGRYAR
     ELNELTPELK KVLPPSDTRY RPDQRILEEG DVAGADSKKE EVEQKQRDRR KELAKKGEEH
     VPRFFRKELD AAGNEIWLSN GTYWKIRNQP GFANTKNLDL WC
//