ID A0A1S3R7U7_SALSA Unreviewed; 1519 AA.
AC A0A1S3R7U7;
DT 12-APR-2017, integrated into UniProtKB/TrEMBL.
DT 12-APR-2017, sequence version 1.
DT 27-MAR-2024, entry version 28.
DE SubName: Full=Calmodulin-regulated spectrin-associated protein 3-like isoform X3 {ECO:0000313|RefSeq:XP_014048196.1};
GN Name=LOC106600930 {ECO:0000313|RefSeq:XP_014048196.1};
OS Salmo salar (Atlantic salmon).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Protacanthopterygii; Salmoniformes;
OC Salmonidae; Salmoninae; Salmo.
OX NCBI_TaxID=8030 {ECO:0000313|Proteomes:UP000087266, ECO:0000313|RefSeq:XP_014048196.1};
RN [1] {ECO:0000313|RefSeq:XP_014048196.1}
RP IDENTIFICATION.
RC TISSUE=Muscle {ECO:0000313|RefSeq:XP_014048196.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- DOMAIN: The CKK domain binds microtubules. {ECO:0000256|PROSITE-
CC ProRule:PRU00841}.
CC -!- SIMILARITY: Belongs to the CAMSAP1 family. {ECO:0000256|PROSITE-
CC ProRule:PRU00841}.
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DR RefSeq; XP_014048196.1; XM_014192721.1.
DR STRING; 8030.ENSSSAP00000028490; -.
DR PaxDb; 8030-ENSSSAP00000028490; -.
DR GeneID; 106600930; -.
DR CTD; 57662; -.
DR OrthoDB; 2918432at2759; -.
DR Proteomes; UP000087266; Chromosome ssa03.
DR GO; GO:0005874; C:microtubule; IEA:UniProtKB-UniRule.
DR GO; GO:0005516; F:calmodulin binding; IEA:InterPro.
DR GO; GO:0008017; F:microtubule binding; IEA:InterPro.
DR GO; GO:0030507; F:spectrin binding; IEA:InterPro.
DR GO; GO:0031175; P:neuron projection development; IEA:InterPro.
DR Gene3D; 3.10.20.360; CKK domain; 1.
DR InterPro; IPR032940; CAMSAP.
DR InterPro; IPR022613; CAMSAP-like_CH_dom.
DR InterPro; IPR031372; CAMSAP_CC1.
DR InterPro; IPR001715; CH_dom.
DR InterPro; IPR036872; CH_dom_sf.
DR InterPro; IPR038209; CKK_dom_sf.
DR InterPro; IPR014797; CKK_domain.
DR InterPro; IPR011033; PRC_barrel-like_sf.
DR PANTHER; PTHR21595:SF2; CALMODULIN-REGULATED SPECTRIN-ASSOCIATED PROTEIN 3; 1.
DR PANTHER; PTHR21595; UNCHARACTERIZED; 1.
DR Pfam; PF17095; CAMSAP_CC1; 1.
DR Pfam; PF11971; CAMSAP_CH; 1.
DR Pfam; PF08683; CAMSAP_CKK; 1.
DR SMART; SM01051; CAMSAP_CKK; 1.
DR SUPFAM; SSF47576; Calponin-homology domain, CH-domain; 1.
DR SUPFAM; SSF50346; PRC-barrel domain; 1.
DR PROSITE; PS50021; CH; 1.
DR PROSITE; PS51508; CKK; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054, ECO:0000256|SAM:Coils};
KW Cytoplasm {ECO:0000256|ARBA:ARBA00023212};
KW Cytoskeleton {ECO:0000256|ARBA:ARBA00023212};
KW Microtubule {ECO:0000256|ARBA:ARBA00022701, ECO:0000256|PROSITE-
KW ProRule:PRU00841}; Reference proteome {ECO:0000313|Proteomes:UP000087266}.
FT DOMAIN 248..362
FT /note="Calponin-homology (CH)"
FT /evidence="ECO:0000259|PROSITE:PS50021"
FT DOMAIN 1380..1514
FT /note="CKK"
FT /evidence="ECO:0000259|PROSITE:PS51508"
FT REGION 223..242
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 477..500
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 540..750
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 779..883
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 899..1061
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1087..1111
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1221..1252
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1323..1377
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 1175..1210
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 227..242
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 602..619
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 620..640
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 646..660
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 715..737
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 805..832
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 935..987
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1029..1047
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1323..1353
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1360..1375
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1519 AA; 165758 MW; 3558500A984D43A7 CRC64;
MLDLNLFLSP PTIFKVSIPL RLPRPVCGLA MVDSNAMRKT FVVPDIKPLD LYDCTRAKIC
ASVGWVLAKS YGNAEHVPVE LREPFYCDQY EQEHLKPPVT RLLLSSELYC RTYGLLQGDQ
GGSGAPKDNA TLLQLLANRG VTPKDQDVPV TDEDLRHKPI KMSAHLAVMD ALMSVGAMET
VSAVRMSGAA TGEELLGGVG EASWENTLLH WVNGLNQRLR EQTEGALGDP SQDSTEPQPV
QPSCPTRWYW KLVPIRYRKD KTLSKQKPTF PVVTEVKDLS NGCAIAAIVH YYCPGLLQLE
DVCMKESMAV EDSLYNLQLI REFCDSCLKS CCPLVLEDLL YTPQELQVNT MSFLAELLGW
FEVRRPEFVQ PLNTTDASAT LKPTSLSNNS GSPSIFKKPF LPISSPVSPG PAPERAGRTW
TKKPFSRPLS SAVSFSIPFG LDSDVDVVMG GAITRSVSSD NVAPGLTITR VPYTPPEDLS
HLLSKPPAPP GSHRGSWATQ SSSVVPMLLK ENGLGDGEGD GELPTIEEAL QIIHNEDKME
PRLHPDGAAD GFFLHSPDDP ASARRNGRAA HPSHPPNPIP LSCSAPSHSG MMYYPHTPMG
GKTQQPREQP SSTPSSRTRH TSEGSRDDDS VLRDGSVDSD ASEDLLLLPN AQSTPATSAV
HARSCGGGGD APDSGVRMTS FAERKKKPST VGESPKSGGA SSSEPVAPAA TAPMTSWVAQ
PQKSTEESPS KSPGLTTEMS ELGARLDEKR KAIEAQKKRI EAIFAKHRQR LGKSAFLQLK
KDQGVGERAE EEGGQVSASS TEEDLRGLTL DERLARMEDE EQQEERRLSL EQEGNVKPSS
HLDNKQASLP RREKGAGAAG PAGPGGEQAG VVARQPAPLG DYNNAVSKLN AALSSLQSDM
QRLSEQQNQL IRKKPVAPAG NKSWVIPPSL KSQAPPPTRM SRASTPRDLA SASSSPSSSR
RNAASPGRTS KSPQVQRRAQ SVPPKSPKHQ ATHYHHARPQ DLKVPGLSRV LTPPQNVDTI
PHLRRASPWQ CRDQNSSTFN ISSAPSPAST PTPTPTPRAL SLALDDNMSD AGSNEDQSIF
SIDLDTATSQ ASGRKEHGGG GSSGAPSECS FESDVPAAGV FNGKRSSLIE ISLSALCGDE
DDLSVMDDSM SDVTEPEMKG GVGFFFKDDK VRPEDEMAQR KAALMEKQRK RAEEMKRRRL
EQEEKREKEH AIRPEWFNIE GWGDKCGGSG EDRTPGTPPS ESTSQRRDTF TRQEYERRQQ
LKIMEDLDKV LRQKPTTVRG VKKQRPKTMF RDDSVLSRSP AKGFMGSKLN KVYSHSTMNL
SSMANDTGNS GTLTVRKSPS RSHSPSRLMS PGRMANQNGE KDWENASTAS SPASIPEYTG
PKLYKEPSFK SNKFIIHNAI SRCCLAGKVN EPQKNKIVEE MEKCQANHFL ILFRDSSCQF
RAVYTMNPET EEMVRLTGIG PRVISPAMVE SIYKYSSDRK QFTTIPSKTM SMSVDAFTIP
GHLWQSKRPG TPKKLGTPK
//
