ID A0A1S3R9A4_SALSA Unreviewed; 565 AA.
AC A0A1S3R9A4;
DT 12-APR-2017, integrated into UniProtKB/TrEMBL.
DT 12-APR-2017, sequence version 1.
DT 27-MAR-2024, entry version 25.
DE RecName: Full=peptidylprolyl isomerase {ECO:0000256|PROSITE-ProRule:PRU00277};
DE EC=5.2.1.8 {ECO:0000256|PROSITE-ProRule:PRU00277};
GN Name=LOC106601011 {ECO:0000313|RefSeq:XP_014048329.1};
OS Salmo salar (Atlantic salmon).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Protacanthopterygii; Salmoniformes;
OC Salmonidae; Salmoninae; Salmo.
OX NCBI_TaxID=8030 {ECO:0000313|Proteomes:UP000087266, ECO:0000313|RefSeq:XP_014048329.1};
RN [1] {ECO:0000313|RefSeq:XP_014048329.1}
RP IDENTIFICATION.
RC TISSUE=Muscle {ECO:0000313|RefSeq:XP_014048329.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=[protein]-peptidylproline (omega=180) = [protein]-
CC peptidylproline (omega=0); Xref=Rhea:RHEA:16237, Rhea:RHEA-
CC COMP:10747, Rhea:RHEA-COMP:10748, ChEBI:CHEBI:83833,
CC ChEBI:CHEBI:83834; EC=5.2.1.8; Evidence={ECO:0000256|PROSITE-
CC ProRule:PRU00277};
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DR RefSeq; XP_014048329.1; XM_014192854.1.
DR AlphaFoldDB; A0A1S3R9A4; -.
DR STRING; 8030.ENSSSAP00000004918; -.
DR PaxDb; 8030-ENSSSAP00000004918; -.
DR Ensembl; ENSSSAT00000005307; ENSSSAP00000004953; ENSSSAG00000002438.
DR GeneID; 106601011; -.
DR KEGG; sasa:106601011; -.
DR OrthoDB; 25281at2759; -.
DR Proteomes; UP000087266; Chromosome ssa03.
DR Bgee; ENSSSAG00000002438; Expressed in sexually immature organism and 14 other cell types or tissues.
DR GO; GO:0005783; C:endoplasmic reticulum; IEA:UniProt.
DR GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR GO; GO:0003755; F:peptidyl-prolyl cis-trans isomerase activity; IEA:UniProtKB-KW.
DR Gene3D; 3.10.50.40; -; 4.
DR Gene3D; 1.10.238.10; EF-hand; 1.
DR InterPro; IPR011992; EF-hand-dom_pair.
DR InterPro; IPR002048; EF_hand_dom.
DR InterPro; IPR046357; PPIase_dom_sf.
DR InterPro; IPR001179; PPIase_FKBP_dom.
DR PANTHER; PTHR46046; PEPTIDYLPROLYL ISOMERASE; 1.
DR PANTHER; PTHR46046:SF7; PEPTIDYLPROLYL ISOMERASE; 1.
DR Pfam; PF00254; FKBP_C; 4.
DR SUPFAM; SSF47473; EF-hand; 1.
DR SUPFAM; SSF54534; FKBP-like; 4.
DR PROSITE; PS50222; EF_HAND_2; 1.
DR PROSITE; PS50059; FKBP_PPIASE; 4.
PE 4: Predicted;
KW Isomerase {ECO:0000256|PROSITE-ProRule:PRU00277,
KW ECO:0000313|RefSeq:XP_014048329.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000087266};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Rotamase {ECO:0000256|PROSITE-ProRule:PRU00277};
KW Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..19
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 20..565
FT /note="peptidylprolyl isomerase"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5010295575"
FT DOMAIN 45..133
FT /note="PPIase FKBP-type"
FT /evidence="ECO:0000259|PROSITE:PS50059"
FT DOMAIN 157..245
FT /note="PPIase FKBP-type"
FT /evidence="ECO:0000259|PROSITE:PS50059"
FT DOMAIN 269..357
FT /note="PPIase FKBP-type"
FT /evidence="ECO:0000259|PROSITE:PS50059"
FT DOMAIN 381..468
FT /note="PPIase FKBP-type"
FT /evidence="ECO:0000259|PROSITE:PS50059"
FT DOMAIN 524..559
FT /note="EF-hand"
FT /evidence="ECO:0000259|PROSITE:PS50222"
SQ SEQUENCE 565 AA; 62608 MW; 79560B32986C2B80 CRC64;
MESMFALILL CVTGTHVSSS PGPLEDVVID RYDIPRVCPR EVQTGDFVRY HYNGTFTDGK
KFDSSHERGA PFSGQVGLGR LITGLDRGVQ GMCVNERRKV TVPPHLAYGS IGAGDVIPAD
TVLVFDVVLL DIWNTEDKVQ TRTLSKPESC KRLVEATDFI RYHYNGTLLN GVPFDSSHSR
NGTYDTYVGM GYLIKGMDEG LIGMCVGETR TIIIPPFLAY EEKGYGTVIP SQATLVFEVF
MIDLFNPKDD ITVVVKEVPK TCTRKTVVGD YIRYHYNGTF QDGSGFDTSY QRNSTYNTYI
GMGYVIQGMD KALQGLCIGE KRRVILPPHM AYGEKGTGDL IPGSAVLIFD IHVIDFHNPK
DLIEIKVTSK PKKCNLTSEV DDLIQYRYNC SLMDGTLLYS SDHYENAPIT TLGANKVIEG
LDEGLRGMCV GEKRVVIVPP HLGHGENGAK GVPSSAVLHF ELELLDLQKG VPDGYMFVWL
GDSPDPLFPA MDLNKDLSVP LEEFTAFINI QVAEGTGRLR PGMDADGIIK DMFNNQDRNT
DGKIVAEELK LKVEEDSDRA RHEEL
//
