ID A0A1S3RAY6_SALSA Unreviewed; 806 AA.
AC A0A1S3RAY6;
DT 12-APR-2017, integrated into UniProtKB/TrEMBL.
DT 12-APR-2017, sequence version 1.
DT 27-MAR-2024, entry version 23.
DE RecName: Full=Phosphoinositide 3-kinase regulatory subunit 5 {ECO:0000256|ARBA:ARBA00040195};
GN Name=LOC106601370 {ECO:0000313|RefSeq:XP_014049022.1};
OS Salmo salar (Atlantic salmon).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Protacanthopterygii; Salmoniformes;
OC Salmonidae; Salmoninae; Salmo.
OX NCBI_TaxID=8030 {ECO:0000313|Proteomes:UP000087266, ECO:0000313|RefSeq:XP_014049022.1};
RN [1] {ECO:0000313|RefSeq:XP_014049022.1}
RP IDENTIFICATION.
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
CC Membrane {ECO:0000256|ARBA:ARBA00004170}; Peripheral membrane protein
CC {ECO:0000256|ARBA:ARBA00004170}. Nucleus
CC {ECO:0000256|ARBA:ARBA00004123}.
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DR RefSeq; XP_014049022.1; XM_014193547.1.
DR AlphaFoldDB; A0A1S3RAY6; -.
DR STRING; 8030.ENSSSAP00000090477; -.
DR PaxDb; 8030-ENSSSAP00000025693; -.
DR GeneID; 106601370; -.
DR KEGG; sasa:106601370; -.
DR OrthoDB; 5349388at2759; -.
DR Proteomes; UP000087266; Chromosome ssa03.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0005944; C:phosphatidylinositol 3-kinase complex, class IB; IEA:InterPro.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0046935; F:1-phosphatidylinositol-3-kinase regulator activity; IEA:InterPro.
DR InterPro; IPR019522; PIK3R5/6.
DR PANTHER; PTHR15593; PHOSPHATIDYLINOSITOL 3-KINASE REGULATORY SUBUNIT; 1.
DR PANTHER; PTHR15593:SF2; PHOSPHOINOSITIDE 3-KINASE REGULATORY SUBUNIT 5; 1.
DR Pfam; PF10486; PI3K_1B_p101; 1.
PE 4: Predicted;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Membrane {ECO:0000256|ARBA:ARBA00023136};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000087266}.
FT REGION 315..341
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 367..478
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 389..404
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 408..426
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT NON_TER 806
FT /evidence="ECO:0000313|RefSeq:XP_014049022.1"
SQ SEQUENCE 806 AA; 89325 MW; 501DB183C2F7830F CRC64;
MEHTSCTEDR IHHALDRCLY GLGHSSPNTQ PWNAGLCINR WSLEELVKRD PQNFIILLQQ
ILRKTREVLE QSQDELVVPL ALLFSSTLLQ TPHFSPDSGV LQDACEVFHC FLSWPEPCCS
ASRHLLSLIQ QELRAPGISF QRLVREEQGL TTTTNHSKTM TVLLMSPGED VPPELLYFSE
QLSGVCHSQR DTSITLIKHA FQAALGTKYP LQILHHALQS KGAEDLEQLV TAVTEALETA
ASTRDPDTAR ESLLQSLKGL VESIGMSPPD CHTGPGNVHT LTLPLAKCHM YSWDKDNFDI
LNDLLQSELD QLPVLNLPRD KGEEEDEDEE TEEETIKNRY TDHRISTVST CSKDSMFSSY
SLSSSLSVPS TLSESSGVDS DFSEDLETDD GQPENRRRPE SKVHLSQRFS MLFKSQRSSS
LCRRAQSMGS RGDVTRDGPS GALFKRSKSL PRQVRLPRLP RSSGVPAPTS DGPFPQSHHV
CVRKRPILSC EEGDGVEMST LVRVVVFGGD REAGRLARAY TDLQQRESRC PRLTRAYRLQ
FYFVPVKRGN LGGPGGLSIV PEGHLGSLKK CPTSTKSNAV ILEDSTTDIA HLIGMTDPWY
KQSVLSLLSL SSDVLCQTTS KVDCDSDNSS SERLLLLADL VLYYCRNAAQ PVLLQLYQAE
LTLAGGEKRR EVFIHSLELG HTAGTRAVKA MGAASKRFGI DGDREALPLA LDVIYNKVCV
SGRSQRTETD MVCTSINLRK ACKGPEQLDS KMDSLHLTMT EVLKIQSSKS KKNYNQHISR
SEVKVDKVQV SGGSGTTFPV CLDQDE
//
