ID A0A1S3RD05_SALSA Unreviewed; 1820 AA.
AC A0A1S3RD05;
DT 12-APR-2017, integrated into UniProtKB/TrEMBL.
DT 12-APR-2017, sequence version 1.
DT 27-MAR-2024, entry version 22.
DE SubName: Full=Trinucleotide repeat-containing gene 6C protein-like isoform X8 {ECO:0000313|RefSeq:XP_014049644.1};
GN Name=LOC106601795 {ECO:0000313|RefSeq:XP_014049644.1};
OS Salmo salar (Atlantic salmon).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Protacanthopterygii; Salmoniformes;
OC Salmonidae; Salmoninae; Salmo.
OX NCBI_TaxID=8030 {ECO:0000313|Proteomes:UP000087266, ECO:0000313|RefSeq:XP_014049644.1};
RN [1] {ECO:0000313|RefSeq:XP_014049644.1}
RP IDENTIFICATION.
RC TISSUE=Muscle {ECO:0000313|RefSeq:XP_014049644.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR RefSeq; XP_014049644.1; XM_014194169.1.
DR Proteomes; UP000087266; Chromosome ssa03.
DR GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR GO; GO:0006417; P:regulation of translation; IEA:UniProtKB-KW.
DR CDD; cd14283; UBA_TNR6C; 1.
DR Gene3D; 3.30.70.330; -; 1.
DR Gene3D; 1.10.8.10; DNA helicase RuvA subunit, C-terminal domain; 1.
DR InterPro; IPR026805; GW182_M_dom.
DR InterPro; IPR012677; Nucleotide-bd_a/b_plait_sf.
DR InterPro; IPR035979; RBD_domain_sf.
DR InterPro; IPR041917; TNR6C_UBA.
DR InterPro; IPR032226; TNRC6_PABC-bd.
DR InterPro; IPR015940; UBA.
DR InterPro; IPR009060; UBA-like_sf.
DR PANTHER; PTHR13020; TRINUCLEOTIDE REPEAT-CONTAINING GENE 6; 1.
DR PANTHER; PTHR13020:SF9; TRINUCLEOTIDE REPEAT-CONTAINING GENE 6C PROTEIN; 1.
DR Pfam; PF12938; M_domain; 1.
DR Pfam; PF16608; TNRC6-PABC_bdg; 1.
DR Pfam; PF00627; UBA; 1.
DR SMART; SM00165; UBA; 1.
DR SUPFAM; SSF54928; RNA-binding domain, RBD; 1.
DR SUPFAM; SSF46934; UBA-like; 1.
DR PROSITE; PS50030; UBA; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Reference proteome {ECO:0000313|Proteomes:UP000087266};
KW Translation regulation {ECO:0000256|ARBA:ARBA00022845}.
FT DOMAIN 1154..1199
FT /note="UBA"
FT /evidence="ECO:0000259|PROSITE:PS50030"
FT REGION 1..1154
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1226..1279
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1393..1442
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1463..1539
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1562..1588
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1600..1707
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 1179..1206
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 1353..1384
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 1..28
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 33..50
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 51..78
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 115..132
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 150..196
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 203..243
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 299..318
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 344..358
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 359..439
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 455..479
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 493..514
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 522..551
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 556..570
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 685..707
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 831..845
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 940..954
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1008..1023
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1125..1140
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1240..1263
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1421..1442
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1463..1493
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1569..1588
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1608..1644
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1655..1672
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1820 AA; 188143 MW; 5AF0788A3E0D5535 CRC64;
MEEKKKRRQE EKKKKEAAQK KVTEQKTKVP DSAKPGPTPP PPPANPSATP SVPPTSGSNG
KRASSSAQQQ SQPSPAQQRY PPREIPPRFR QQEHKQLLKR GQPLPPGTLP TVPGRPEPDS
SQKSSGASHT ELPPQSGPGA YYENPHWGHQ PANRSATSAS ASANHSGWDT VIINESDTEA
WPSISRSSQS QGPAGGCPSD TDPVGPASSS SMSMATGANG QTGHFPANYP SSKGASSGPG
SSANHPGAGM VGMASSQGAA NRGWGSGPGP SPHGPPQSSS VVGGEGKSDG PMGGGGGRGW
GSSSSTNFNL NLNPNANPSA WPVLGHDGGG GAGGSSSGGA NPNQPPSSQP PPNLCNPPGT
SPAQGNSNRG GTMVGGTNGN LPVGGGSTWG ESSEPHPSSS TNVSFSSEPQ NLNTDGPNHT
SKQQEPPIHS VSGWSGPSGG MGSLGQPPPG ASQLVNGEDG SSVWGNNGDS KSVASSAEPS
GWDSGAGGWG SHGSSGGGTS GGWGGQSSGD AWGKQHSGEG QGGWEAPSST PQQASSWSTR
APSTTAASEG SSEGMEGAGH SRRQDRSSRD EPAPLLPAPD LDPRVLCNTG WGQTPVRQHT
SWDMEEAART QRKADAAGAD SWGGSGPNTP TEPAQGPSNP SHGPPHRADL KSDVPGPGPQ
AATGWGGSMP PASQLGSGWG EPPSSKNPPN GPGGWGNPPP GGPGPGPNMP KAGNQSWGAP
EEKSPSWDDP HGKAPKPQGW GDGPKLPHSG WGNSAGGGGN GGDWREPADG KKNSPTTNPP
WEGEGAGGWK ESNRGWGKPG PGMGGNVGGG GGWGEPAMAQ QRPSGPAQGW GGKPQESSNG
NSGGVRGGSM GGAGGGEGSM GSWGGPGPVK PSVSGREGNG GGGGSKQDPS GGEPTGWEEP
SPPSIRRKME IDDGTSAWGD PGAYNKTVNL WDKNNPGGGG PPQGRPPGNA PGNAPACPPG
NNNNHPHPPH HPPHHPHTYH GPPPPLQSHG GHNPQGPGQN SGPMDPAMPH QAAPPPHSRP
PLMGPGWGEP SSAHPKPEPS WGEPAPPPVS VDNGTSAWGK PTGSHGGWGV GDNSPEPYRR
GNPPLGSAPC KPAPKSMQDG WGGGSGGGGE DMGLSGGQWD PDDGDMWSSQ ASQESNSWGN
RPRKGPPKGK ILGKQEEAWI MNRLIKQLTD MGFPRDPAEE ALKRNNMNLD QAMSALLEKK
TELDRRGMGM SDYNNCLINK GPMGCRPPLH SKESSSDRSS FLDKMQSGML GSSGAAQARA
MQQPPPQPSV PPLGSSQPSL RAQVPQFLSP QVQAQLLQFA AKNIGLNPAL LTSPINPQHM
TLLNQLYQLQ LAYQRLQIQQ QMLQAQRNVS APIRQQEQHV ARTINNMQQQ IQQHQRQLAQ
ALLMKQQQTL GSLSSSGLHH GQGKSALDLF PGHPQAPGLP DLQTKEQQSS TNSYSLYPLS
GLNPNMNVTG IEVGGLSMKE LPQPQSRLSQ WTHPNSMDSL SGGSSSLEPN LNKHGSNLGP
PGKPPQMEDG YSPYGMMPGS ESPTNPLVPP DSWSQGKSPN DKMVNGTNIT WPPEFCPGVP
WKGLQNIDPE NDPNMTPGSV PSGPTINTNI QDVNRYLQRD RSGGCDAPIG SSPTSSQNEA
LPPSTDWPVS AYSSSFSLSS PETDDPGKLS DMKSTWSPGP ISHPSQVSLS HELWKVPQGP
RSNTAAPTRP PPGLTNPTKH SSTWGGNSLG LAQGWSSSYS SAATTWSTDS SNRTSSWLVL
RNLTPQIDGS TLRTLCMQHG PLITFHLNLT QGNALVRYSS KEEAAKAQKS LHMYGDVVGS
FPAPLTARRQ KHLCHVNCQV
//
