ID A0A1S3RGK0_SALSA Unreviewed; 681 AA.
AC A0A1S3RGK0;
DT 12-APR-2017, integrated into UniProtKB/TrEMBL.
DT 12-APR-2017, sequence version 1.
DT 27-MAR-2024, entry version 30.
DE SubName: Full=Regulator of G-protein signaling 14-like isoform X2 {ECO:0000313|RefSeq:XP_014051410.1};
GN Name=LOC106602924 {ECO:0000313|RefSeq:XP_014051410.1};
OS Salmo salar (Atlantic salmon).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Protacanthopterygii; Salmoniformes;
OC Salmonidae; Salmoninae; Salmo.
OX NCBI_TaxID=8030 {ECO:0000313|Proteomes:UP000087266, ECO:0000313|RefSeq:XP_014051410.1};
RN [1] {ECO:0000313|RefSeq:XP_014051410.1}
RP IDENTIFICATION.
RC TISSUE=Muscle {ECO:0000313|RefSeq:XP_014051410.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
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DR RefSeq; XP_014051410.1; XM_014195935.1.
DR AlphaFoldDB; A0A1S3RGK0; -.
DR OrthoDB; 22856at2759; -.
DR Proteomes; UP000087266; Chromosome ssa04.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR GO; GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.
DR GO; GO:0007165; P:signal transduction; IEA:InterPro.
DR CDD; cd17139; RBD2_RGS14; 1.
DR Gene3D; 1.10.196.10; -; 1.
DR Gene3D; 1.10.167.10; Regulator of G-protein Signalling 4, domain 2; 1.
DR InterPro; IPR046993; RBD2_RGS14.
DR InterPro; IPR003116; RBD_dom.
DR InterPro; IPR016137; RGS.
DR InterPro; IPR046995; RGS10/12/14-like.
DR InterPro; IPR036305; RGS_sf.
DR InterPro; IPR024066; RGS_subdom1/3.
DR InterPro; IPR044926; RGS_subdomain_2.
DR InterPro; IPR029071; Ubiquitin-like_domsf.
DR PANTHER; PTHR45945:SF2; REGULATOR OF G-PROTEIN SIGNALING 14; 1.
DR PANTHER; PTHR45945; REGULATOR OF G-PROTEIN SIGNALING LOCO; 1.
DR Pfam; PF02196; RBD; 1.
DR Pfam; PF00615; RGS; 1.
DR PRINTS; PR01301; RGSPROTEIN.
DR SMART; SM00455; RBD; 2.
DR SMART; SM00315; RGS; 1.
DR SUPFAM; SSF48097; Regulator of G-protein signaling, RGS; 1.
DR SUPFAM; SSF54236; Ubiquitin-like; 2.
DR PROSITE; PS50898; RBD; 2.
DR PROSITE; PS50132; RGS; 1.
PE 4: Predicted;
KW GTPase activation {ECO:0000256|ARBA:ARBA00022468};
KW Reference proteome {ECO:0000313|Proteomes:UP000087266}.
FT DOMAIN 112..229
FT /note="RGS"
FT /evidence="ECO:0000259|PROSITE:PS50132"
FT DOMAIN 352..423
FT /note="RBD"
FT /evidence="ECO:0000259|PROSITE:PS50898"
FT DOMAIN 425..495
FT /note="RBD"
FT /evidence="ECO:0000259|PROSITE:PS50898"
FT REGION 235..314
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 593..681
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 263..314
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 654..673
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 681 AA; 75145 MW; 81A7BDC5140F26EE CRC64;
METSASCHCP LRKTTGESRE KKTMMFKEFT KGFSQLALRS SLRRRLGRYN NETSIRPLNL
TRSLAVSDGE LNVVPEERGA SAGLCSSSNS SLPTVPSDGA SGVGKVASWA VSFERLLQDP
TGVLYFTDFL KSEVSAENIL FWQACEKFRQ IPVNQKEKLN QEARSIYSSY LSGSASHPIN
IDDKVRIEEW EVRNPQPDMY HKAQQQIFKL MKFDSYTRFV RSQLYQSCML ANVEGRPLPE
LGPRSKSTAT RKTAGTDIPS LSDRPKADQK PKEKPRVKPG KSLPLDLDEG AEKRKGVPQN
KLTREKGQEK RGSWGAELAD HAAVLQSTAR SGSLLNAAEL EKERWRAGQA EKYCCVFLPD
GTASLAPARP GLSIRTMLTG LCEKRGLPLS DVIIYLQGKD KKPLSLDQDS SVLKEQQVFL
ELRVTFAVEI VSTGKTVGIV VKSSKSLQEA LTPVLQKQRL RPQDVIVTMS GSKESLSMSM
AVTSLANKKI TLDRVKGTEQ SSSSMVCGSS SGPVFQGRRS AVVDVDTSSL FSADRVRTNT
RLRNPAFRRT YDMDGLMELL SRAQCCSVDD QRGLLKKEQL WLPQFLQLPL AEAHEEEDQE
EEQGKRGGGM GGLRGQDGLG LTETELEPSP VHFHAFPEPF QLPSGPPLQF SDTGVGGEEQ
TRPPSSDSQL SDPDPGRETV V
//
