ID A0A1S3RI13_SALSA Unreviewed; 682 AA.
AC A0A1S3RI13;
DT 12-APR-2017, integrated into UniProtKB/TrEMBL.
DT 12-APR-2017, sequence version 1.
DT 27-MAR-2024, entry version 30.
DE SubName: Full=Regulator of G-protein signaling 14-like isoform X1 {ECO:0000313|RefSeq:XP_014051409.1};
GN Name=LOC106602924 {ECO:0000313|RefSeq:XP_014051409.1};
OS Salmo salar (Atlantic salmon).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Protacanthopterygii; Salmoniformes;
OC Salmonidae; Salmoninae; Salmo.
OX NCBI_TaxID=8030 {ECO:0000313|Proteomes:UP000087266, ECO:0000313|RefSeq:XP_014051409.1};
RN [1] {ECO:0000313|RefSeq:XP_014051409.1}
RP IDENTIFICATION.
RC TISSUE=Muscle {ECO:0000313|RefSeq:XP_014051409.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
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DR RefSeq; XP_014051409.1; XM_014195934.1.
DR AlphaFoldDB; A0A1S3RI13; -.
DR GeneID; 106602924; -.
DR KEGG; sasa:106602924; -.
DR CTD; 100003648; -.
DR OrthoDB; 22856at2759; -.
DR Proteomes; UP000087266; Chromosome ssa04.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR GO; GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.
DR GO; GO:0007165; P:signal transduction; IEA:InterPro.
DR CDD; cd17139; RBD2_RGS14; 1.
DR Gene3D; 1.10.196.10; -; 1.
DR Gene3D; 1.10.167.10; Regulator of G-protein Signalling 4, domain 2; 1.
DR InterPro; IPR046993; RBD2_RGS14.
DR InterPro; IPR003116; RBD_dom.
DR InterPro; IPR016137; RGS.
DR InterPro; IPR046995; RGS10/12/14-like.
DR InterPro; IPR036305; RGS_sf.
DR InterPro; IPR024066; RGS_subdom1/3.
DR InterPro; IPR044926; RGS_subdomain_2.
DR InterPro; IPR029071; Ubiquitin-like_domsf.
DR PANTHER; PTHR45945:SF2; REGULATOR OF G-PROTEIN SIGNALING 14; 1.
DR PANTHER; PTHR45945; REGULATOR OF G-PROTEIN SIGNALING LOCO; 1.
DR Pfam; PF02196; RBD; 1.
DR Pfam; PF00615; RGS; 1.
DR PRINTS; PR01301; RGSPROTEIN.
DR SMART; SM00455; RBD; 2.
DR SMART; SM00315; RGS; 1.
DR SUPFAM; SSF48097; Regulator of G-protein signaling, RGS; 1.
DR SUPFAM; SSF54236; Ubiquitin-like; 2.
DR PROSITE; PS50898; RBD; 2.
DR PROSITE; PS50132; RGS; 1.
PE 4: Predicted;
KW GTPase activation {ECO:0000256|ARBA:ARBA00022468};
KW Reference proteome {ECO:0000313|Proteomes:UP000087266}.
FT DOMAIN 112..229
FT /note="RGS"
FT /evidence="ECO:0000259|PROSITE:PS50132"
FT DOMAIN 353..424
FT /note="RBD"
FT /evidence="ECO:0000259|PROSITE:PS50898"
FT DOMAIN 426..496
FT /note="RBD"
FT /evidence="ECO:0000259|PROSITE:PS50898"
FT REGION 235..314
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 594..682
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 263..314
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 655..674
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 682 AA; 75273 MW; 86F598A8160C79C9 CRC64;
METSASCHCP LRKTTGESRE KKTMMFKEFT KGFSQLALRS SLRRRLGRYN NETSIRPLNL
TRSLAVSDGE LNVVPEERGA SAGLCSSSNS SLPTVPSDGA SGVGKVASWA VSFERLLQDP
TGVLYFTDFL KSEVSAENIL FWQACEKFRQ IPVNQKEKLN QEARSIYSSY LSGSASHPIN
IDDKVRIEEW EVRNPQPDMY HKAQQQIFKL MKFDSYTRFV RSQLYQSCML ANVEGRPLPE
LGPRSKSTAT RKTAGTDIPS LSDRPKADQK PKEKPRVKPG KSLPLDLDEG AEKRKGVPQN
KLTREKGQEK RGSWGAELAD HAAVLQSTAR SGSLLNAAEK LEKERWRAGQ AEKYCCVFLP
DGTASLAPAR PGLSIRTMLT GLCEKRGLPL SDVIIYLQGK DKKPLSLDQD SSVLKEQQVF
LELRVTFAVE IVSTGKTVGI VVKSSKSLQE ALTPVLQKQR LRPQDVIVTM SGSKESLSMS
MAVTSLANKK ITLDRVKGTE QSSSSMVCGS SSGPVFQGRR SAVVDVDTSS LFSADRVRTN
TRLRNPAFRR TYDMDGLMEL LSRAQCCSVD DQRGLLKKEQ LWLPQFLQLP LAEAHEEEDQ
EEEQGKRGGG MGGLRGQDGL GLTETELEPS PVHFHAFPEP FQLPSGPPLQ FSDTGVGGEE
QTRPPSSDSQ LSDPDPGRET VV
//
