ID A0A1S3RIX7_SALSA Unreviewed; 798 AA.
AC A0A1S3RIX7;
DT 12-APR-2017, integrated into UniProtKB/TrEMBL.
DT 12-APR-2017, sequence version 1.
DT 27-MAR-2024, entry version 29.
DE SubName: Full=Disks large homolog 4-like isoform X7 {ECO:0000313|RefSeq:XP_014051794.1};
GN Name=LOC106603100 {ECO:0000313|RefSeq:XP_014051794.1};
OS Salmo salar (Atlantic salmon).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Protacanthopterygii; Salmoniformes;
OC Salmonidae; Salmoninae; Salmo.
OX NCBI_TaxID=8030 {ECO:0000313|Proteomes:UP000087266, ECO:0000313|RefSeq:XP_014051794.1};
RN [1] {ECO:0000313|RefSeq:XP_014051794.1}
RP IDENTIFICATION.
RC TISSUE=Muscle {ECO:0000313|RefSeq:XP_014051794.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
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DR RefSeq; XP_014051794.1; XM_014196319.1.
DR AlphaFoldDB; A0A1S3RIX7; -.
DR OrthoDB; 2879721at2759; -.
DR Proteomes; UP000087266; Chromosome ssa04.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0031594; C:neuromuscular junction; IEA:InterPro.
DR GO; GO:0043005; C:neuron projection; IEA:InterPro.
DR GO; GO:0019900; F:kinase binding; IEA:InterPro.
DR GO; GO:0007268; P:chemical synaptic transmission; IEA:InterPro.
DR CDD; cd00071; GMPK; 1.
DR CDD; cd00992; PDZ_signaling; 3.
DR Gene3D; 2.30.42.10; -; 3.
DR Gene3D; 3.30.63.10; Guanylate Kinase phosphate binding domain; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 2.30.30.40; SH3 Domains; 1.
DR InterPro; IPR019583; DLG1-4_PDZ_assoc.
DR InterPro; IPR016313; DLG1-like.
DR InterPro; IPR019590; DLG1_PEST_dom.
DR InterPro; IPR008145; GK/Ca_channel_bsu.
DR InterPro; IPR008144; Guanylate_kin-like_dom.
DR InterPro; IPR020590; Guanylate_kinase_CS.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR001478; PDZ.
DR InterPro; IPR036034; PDZ_sf.
DR InterPro; IPR036028; SH3-like_dom_sf.
DR InterPro; IPR001452; SH3_domain.
DR PANTHER; PTHR23119; DISCS LARGE; 1.
DR PANTHER; PTHR23119:SF33; DISKS LARGE HOMOLOG 4; 1.
DR Pfam; PF00625; Guanylate_kin; 1.
DR Pfam; PF10608; MAGUK_N_PEST; 1.
DR Pfam; PF00595; PDZ; 3.
DR Pfam; PF10600; PDZ_assoc; 1.
DR Pfam; PF00018; SH3_1; 1.
DR PIRSF; PIRSF001741; MAGUK_DLGH; 2.
DR SMART; SM00072; GuKc; 1.
DR SMART; SM01277; MAGUK_N_PEST; 1.
DR SMART; SM00228; PDZ; 3.
DR SMART; SM00326; SH3; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF50156; PDZ domain-like; 3.
DR SUPFAM; SSF50044; SH3-domain; 1.
DR PROSITE; PS00856; GUANYLATE_KINASE_1; 1.
DR PROSITE; PS50052; GUANYLATE_KINASE_2; 1.
DR PROSITE; PS50106; PDZ; 3.
DR PROSITE; PS50002; SH3; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|ARBA:ARBA00023136};
KW Reference proteome {ECO:0000313|Proteomes:UP000087266};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW SH3 domain {ECO:0000256|ARBA:ARBA00022443, ECO:0000256|PROSITE-
KW ProRule:PRU00192}.
FT DOMAIN 110..197
FT /note="PDZ"
FT /evidence="ECO:0000259|PROSITE:PS50106"
FT DOMAIN 205..292
FT /note="PDZ"
FT /evidence="ECO:0000259|PROSITE:PS50106"
FT DOMAIN 383..464
FT /note="PDZ"
FT /evidence="ECO:0000259|PROSITE:PS50106"
FT DOMAIN 498..568
FT /note="SH3"
FT /evidence="ECO:0000259|PROSITE:PS50002"
FT DOMAIN 607..783
FT /note="Guanylate kinase-like"
FT /evidence="ECO:0000259|PROSITE:PS50052"
FT REGION 568..596
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 568..588
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 798 AA; 88291 MW; F9591E007453BA41 CRC64;
MKTAYFLKYR YQDEETPPLE HSPAHLGQGK SAEMLHMSDK NLAAMEAMHG YTPHTHISPI
KPVLMSSGHN PMYTSAVSTL GNSPPVVVNT DTLDGSPYVN GTEGEIEYEE ITLERGNSGL
GFSIAGGTDN PHVGDDPSIF ITKIIPGGAA AQDGRLSVND SILFVNDVDV REVTHSLAVE
ALKEAGAIVR LYVLRRKPAA EKVTEIKLIK GPKGLGFSIA GGVGNQHIPG DNSIYVTKII
EGGAAHKDQR LQIGDKILAV NSVCLEDVMH EDAVGALKNT AEVVYLRVAK PNNLYLNSYN
PPDLTSTYSA HMDTDLGHPT YLGSDYPQAL TPTSPSRFSP VLHSMMGDED LPSLLLPLHF
SSSLPDPPSL PFSPALSVRE PRRVLIHRGS TGLGFNIVGG EDGEGIFISF ILAGGPADLS
GELRKGDQIL SVNGVDLRIA THEQAAAALK NAGQTVTIIA QYRPEEYSRF EAKIHDLREQ
LMNSSMGSGQ TTLRSNPKRG FYIRALFDYD KTADCGFLSQ AVGFRFGDVL HVLDCGDEEW
WQARRVSPQT DVEEVGFIPS KRRVERKEWS RMGTKERDHS RDSLGSQGRD DSQHSYETVT
QVEVHYARPI IILGPIKDRV NDDLLSEFPD KFGSCVPHTT RPKREYEVDG RDYHFVSSRE
QMEKDIQSHR FIEAGQYNSH LYGTSVQSVR EVAEQQGKHC ILDVSANAVR RLQAAQLHPI
AIFVRPKSLE NVLEINTRLT EEQARKGMDR ALKLEQDFIE CFSAVVEGDS FEEVYHKVKT
VIEEQSGPYI WIPTRERL
//
