ID A0A1S3RK85_SALSA Unreviewed; 974 AA.
AC A0A1S3RK85;
DT 12-APR-2017, integrated into UniProtKB/TrEMBL.
DT 12-APR-2017, sequence version 1.
DT 27-MAR-2024, entry version 36.
DE SubName: Full=E3 ubiquitin-protein ligase TRIM37 isoform X1 {ECO:0000313|RefSeq:XP_014052663.1};
GN Name=trim37 {ECO:0000313|RefSeq:XP_014052663.1};
OS Salmo salar (Atlantic salmon).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Protacanthopterygii; Salmoniformes;
OC Salmonidae; Salmoninae; Salmo.
OX NCBI_TaxID=8030 {ECO:0000313|Proteomes:UP000087266, ECO:0000313|RefSeq:XP_014052663.1};
RN [1] {ECO:0000313|RefSeq:XP_014052663.1}
RP IDENTIFICATION.
RC TISSUE=Muscle {ECO:0000313|RefSeq:XP_014052663.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
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DR RefSeq; XP_014052663.1; XM_014197188.1.
DR AlphaFoldDB; A0A1S3RK85; -.
DR GeneID; 106603466; -.
DR KEGG; sasa:106603466; -.
DR OrthoDB; 5487127at2759; -.
DR Proteomes; UP000087266; Chromosome ssa04.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR GO; GO:0016567; P:protein ubiquitination; IEA:InterPro.
DR CDD; cd19779; Bbox2_TRIM37_C-VIII; 1.
DR CDD; cd03773; MATH_TRIM37; 1.
DR CDD; cd16619; mRING-HC-C4C4_TRIM37_C-VIII; 1.
DR Gene3D; 3.30.160.60; Classic Zinc Finger; 1.
DR Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 1.
DR InterPro; IPR003649; Bbox_C.
DR InterPro; IPR002083; MATH/TRAF_dom.
DR InterPro; IPR008974; TRAF-like.
DR InterPro; IPR037299; TRIM37_MATH.
DR InterPro; IPR000315; Znf_B-box.
DR InterPro; IPR001841; Znf_RING.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR PANTHER; PTHR36754; E3 UBIQUITIN-PROTEIN LIGASE TRIM37; 1.
DR PANTHER; PTHR36754:SF2; E3 UBIQUITIN-PROTEIN LIGASE TRIM37; 1.
DR Pfam; PF00917; MATH; 1.
DR Pfam; PF00643; zf-B_box; 1.
DR SMART; SM00502; BBC; 1.
DR SMART; SM00336; BBOX; 1.
DR SMART; SM00061; MATH; 1.
DR SUPFAM; SSF57845; B-box zinc-binding domain; 1.
DR SUPFAM; SSF57850; RING/U-box; 1.
DR SUPFAM; SSF49599; TRAF domain-like; 1.
DR PROSITE; PS50144; MATH; 1.
DR PROSITE; PS50119; ZF_BBOX; 1.
DR PROSITE; PS50089; ZF_RING_2; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000087266};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00024}.
FT DOMAIN 15..55
FT /note="RING-type"
FT /evidence="ECO:0000259|PROSITE:PS50089"
FT DOMAIN 90..132
FT /note="B box-type"
FT /evidence="ECO:0000259|PROSITE:PS50119"
FT DOMAIN 276..403
FT /note="MATH"
FT /evidence="ECO:0000259|PROSITE:PS50144"
FT REGION 447..551
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 630..660
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 689..739
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 770..833
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 133..167
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 523..540
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 644..658
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 796..832
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 974 AA; 107664 MW; 052E013116D6EBCB CRC64;
MDEQSVESIA EVFRCFICME KLRDARLCPH CSKLCCFSCI RRWLTEQRAQ CPHCRAPLQL
RELVNCRWAE EVTQQLDTLQ LCNLSKHEEN DKDKCENHHE KLSVFCWTCK KCICHQCALW
GGMHGGHTFK PLAEIYEQHV SKVNEEVAKL RRRLMELISL VQEVERNVEA VRGAKDERVR
EIRNAVEMMI ARLDNQLKNK LITLMGQKTS LTQETELLES LLQEVEHQLR SCSKSELISK
SPEILLMFQQ VHRKPMQSFV TTPVPPDFTS ELVPAYDSST FVLANFSTLR QRADPVYSPP
LQISGICWRL KVYPDGNGVV RGNYLSVFLE LSAGLPETSK YEYRVEMVHQ ASSDPTKNII
REFASDFEVG ECWGYNRFFR LDLLASEGYL NMQTDTLVLR YQVRSPTFFQ KCRDQYWYIS
QLESAQSSYI QQINNLKERL AIELFRRQKS GSSSPPDRRL GPSTSERDSR SGKGPVAEDG
CQTTATETKE EEEEEEKTQH DDSNELSDGD LEVDCLTGDE EVNPLDGSST SGSSTATSNT
EENDIDEETM SGENDVEFSG NLEMEEGELP DDVAGAAGGS NHGARCLRRG GGLSSTGSNN
SLLEIDPVIL IQLLDLKEHS NVESLWGLQP RPPASLLHSQ VQVQSRKERG ERRPQAVRRG
APDSGVLIRL KAQMAEVRSK MTDVKFQLEA RGEVRAGPSG GATGEQGPSY HADSDLGPSR
KSTELDLMGK GPGASRHCRS GSWGAIDCSV RCSSSCDAVV CVAGGKKALS PKQECSGLGL
RRATDGVEKE SRGQSGEELS TPNGSEGALK PHSMQSSPPS LGSSSSCSDS KPCISKHDQE
QLYGADLYAL GGLNGISTST IARPRTQPMG SGLLTDSSLD CDLEETAEVR QSLLSLAEGP
SSHPDESHLV HKQTVVLLPG MSSDSEIDCD TENEDEVVAL EAGDCRYDAQ TLPCAGAQLN
SDDLCFTTGE NTER
//
