GenomeNet

Database: UniProt
Entry: A0A1S3RMF3_SALSA
LinkDB: A0A1S3RMF3_SALSA
Original site: A0A1S3RMF3_SALSA 
ID   A0A1S3RMF3_SALSA        Unreviewed;       529 AA.
AC   A0A1S3RMF3;
DT   12-APR-2017, integrated into UniProtKB/TrEMBL.
DT   12-APR-2017, sequence version 1.
DT   31-JUL-2019, entry version 16.
DE   SubName: Full=G protein-activated inward rectifier potassium channel 3-like {ECO:0000313|RefSeq:XP_014053001.1, ECO:0000313|RefSeq:XP_014053002.1};
GN   Name=LOC106603636 {ECO:0000313|RefSeq:XP_014053001.1,
GN   ECO:0000313|RefSeq:XP_014053002.1};
OS   Salmo salar (Atlantic salmon).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Protacanthopterygii;
OC   Salmoniformes; Salmonidae; Salmoninae; Salmo.
OX   NCBI_TaxID=8030 {ECO:0000313|Proteomes:UP000087266, ECO:0000313|RefSeq:XP_014053002.1};
RN   [1] {ECO:0000313|RefSeq:XP_014053001.1, ECO:0000313|RefSeq:XP_014053002.1}
RP   IDENTIFICATION.
RC   TISSUE=Muscle {ECO:0000313|RefSeq:XP_014053001.1,
RC   ECO:0000313|RefSeq:XP_014053002.1};
RG   RefSeq;
RL   Submitted (JUN-2017) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|RuleBase:RU003822};
CC       Multi-pass membrane protein {ECO:0000256|RuleBase:RU003822}.
CC   -!- SIMILARITY: Belongs to the inward rectifier-type potassium channel
CC       (TC 1.A.2.1) family. {ECO:0000256|RuleBase:RU003822,
CC       ECO:0000256|SAAS:SAAS00549381}.
CC   -----------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   -----------------------------------------------------------------------
DR   RefSeq; XP_014053001.1; XM_014197526.1.
DR   RefSeq; XP_014053002.1; XM_014197527.1.
DR   GeneID; 106603636; -.
DR   KEGG; sasa:106603636; -.
DR   OrthoDB; 956263at2759; -.
DR   Proteomes; UP000087266; Genome assembly.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005242; F:inward rectifier potassium channel activity; IEA:InterPro.
DR   GO; GO:0034765; P:regulation of ion transmembrane transport; IEA:UniProtKB-KW.
DR   Gene3D; 2.60.40.1400; -; 1.
DR   InterPro; IPR014756; Ig_E-set.
DR   InterPro; IPR041647; IRK_C.
DR   InterPro; IPR016449; K_chnl_inward-rec_Kir.
DR   InterPro; IPR013518; K_chnl_inward-rec_Kir_cyto.
DR   InterPro; IPR040445; Kir_TM.
DR   PANTHER; PTHR11767; PTHR11767; 1.
DR   Pfam; PF01007; IRK; 1.
DR   Pfam; PF17655; IRK_C; 1.
DR   PIRSF; PIRSF005465; GIRK_kir; 1.
DR   PRINTS; PR01320; KIRCHANNEL.
DR   SUPFAM; SSF81296; SSF81296; 1.
PE   3: Inferred from homology;
KW   Complete proteome {ECO:0000313|Proteomes:UP000087266};
KW   Ion channel {ECO:0000256|RuleBase:RU003822,
KW   ECO:0000256|SAAS:SAAS00434609, ECO:0000313|RefSeq:XP_014053001.1,
KW   ECO:0000313|RefSeq:XP_014053002.1};
KW   Ion transport {ECO:0000256|RuleBase:RU003822,
KW   ECO:0000256|SAAS:SAAS00434639};
KW   Membrane {ECO:0000256|SAAS:SAAS00434581, ECO:0000256|SAM:Phobius};
KW   Potassium {ECO:0000256|RuleBase:RU003822,
KW   ECO:0000256|SAAS:SAAS00434575};
KW   Potassium transport {ECO:0000256|RuleBase:RU003822,
KW   ECO:0000256|SAAS:SAAS00434641};
KW   Reference proteome {ECO:0000313|Proteomes:UP000087266};
KW   Transmembrane {ECO:0000256|RuleBase:RU003822,
KW   ECO:0000256|SAAS:SAAS00434543, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAAS:SAAS00036756,
KW   ECO:0000256|SAM:Phobius};
KW   Transport {ECO:0000256|RuleBase:RU003822,
KW   ECO:0000256|SAAS:SAAS00036755};
KW   Voltage-gated channel {ECO:0000256|RuleBase:RU003822,
KW   ECO:0000256|SAAS:SAAS00048561}.
FT   TRANSMEM    241    263       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    318    341       Helical. {ECO:0000256|SAM:Phobius}.
FT   DOMAIN      207    346       IRK. {ECO:0000259|Pfam:PF01007}.
FT   DOMAIN      353    524       IRK_C. {ECO:0000259|Pfam:PF17655}.
FT   REGION       14     55       Disordered. {ECO:0000256|SAM:MobiDB-
FT                                lite}.
FT   REGION       79    114       Disordered. {ECO:0000256|SAM:MobiDB-
FT                                lite}.
FT   COMPBIAS     79     95       Polar. {ECO:0000256|SAM:MobiDB-lite}.
FT   COMPBIAS     96    110       Pro-rich. {ECO:0000256|SAM:MobiDB-lite}.
FT   SITE        332    332       Role in the control of polyamine-mediated
FT                                channel gating and in the blocking by
FT                                intracellular magnesium.
FT                                {ECO:0000256|PIRSR:PIRSR005465-1}.
SQ   SEQUENCE   529 AA;  59888 MW;  08D635CB29E6EE5D CRC64;
     MAFTMMCSRV TLHEPHNSDY RSPTRIDPRR NSIPPAQTLT AKHLPRPPPE STRFTPYPKR
     VAAKINMDLT MLHSTRVSLI PSSNNNNDNF PVLSPQPSPS ASPQPQPQSP GPHQVVAGLI
     SQEVDTCQYI IPTEEPEEPA TSHRGRHLKR FSSRWYSGAP FGGPFGSTRS SAHGTSGENK
     PHKLRCKLLG DERPSYGTAN KQRQRYVTKD GKCQVNLGPI EDKSRFLLDI FTTLVDLKYR
     WFLFVFTMCY VVTWVAFAEI YFLDAWLRDD VAHVHDPQWQ PCFENVDSFI SALLLSVESQ
     RTIGYGSRLV TANCMEGVVL LMAQSIIGSI IDALMVGCMF VKISRPQKRA QTLIFSKHCV
     ISERDEKLCL LFRIGDLRAS HMVDAKIRAK LIKSRQTKEG EFIPLEQSEI NLGYDTGGDR
     LLLVEPQTIT HVINESSPFW EIGAERLTRE RFEIIIILEG IVEASGMICQ ARTSYTEDEI
     LWGHRFESCM SLEKGSYRVD RGAFDKTFTV QTPTISAKEK SDEKEEVLF
//
DBGET integrated database retrieval system