ID A0A1S3RN09_SALSA Unreviewed; 2190 AA.
AC A0A1S3RN09;
DT 12-APR-2017, integrated into UniProtKB/TrEMBL.
DT 12-APR-2017, sequence version 1.
DT 27-MAR-2024, entry version 38.
DE SubName: Full=Unconventional myosin-VIIa-like isoform X10 {ECO:0000313|RefSeq:XP_014053207.1};
GN Name=LOC106603713 {ECO:0000313|RefSeq:XP_014053207.1};
OS Salmo salar (Atlantic salmon).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Protacanthopterygii; Salmoniformes;
OC Salmonidae; Salmoninae; Salmo.
OX NCBI_TaxID=8030 {ECO:0000313|Proteomes:UP000087266, ECO:0000313|RefSeq:XP_014053207.1};
RN [1] {ECO:0000313|RefSeq:XP_014053207.1}
RP IDENTIFICATION.
RC TISSUE=Muscle {ECO:0000313|RefSeq:XP_014053207.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the TRAFAC class myosin-kinesin ATPase
CC superfamily. Myosin family. {ECO:0000256|ARBA:ARBA00008314,
CC ECO:0000256|PROSITE-ProRule:PRU00782}.
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DR RefSeq; XP_014053207.1; XM_014197732.1.
DR GeneID; 106603713; -.
DR OrthoDB; 1094820at2759; -.
DR Proteomes; UP000087266; Chromosome ssa04.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR GO; GO:0016459; C:myosin complex; IEA:UniProtKB-KW.
DR GO; GO:0120025; C:plasma membrane bounded cell projection; IEA:UniProt.
DR GO; GO:0003779; F:actin binding; IEA:UniProtKB-KW.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0003774; F:cytoskeletal motor activity; IEA:UniProtKB-UniRule.
DR GO; GO:0048731; P:system development; IEA:UniProt.
DR CDD; cd17092; FERM1_F1_Myosin-VII; 1.
DR CDD; cd17093; FERM2_F1_Myosin-VII; 1.
DR CDD; cd14473; FERM_B-lobe; 2.
DR CDD; cd13198; FERM_C1_MyoVII; 1.
DR CDD; cd13199; FERM_C2_MyoVII; 1.
DR CDD; cd01381; MYSc_Myo7; 1.
DR CDD; cd22249; UDM1_RNF168_RNF169-like; 1.
DR Gene3D; 1.10.10.820; -; 1.
DR Gene3D; 1.20.5.190; -; 2.
DR Gene3D; 1.20.58.530; -; 1.
DR Gene3D; 1.20.80.10; -; 2.
DR Gene3D; 6.20.240.20; -; 1.
DR Gene3D; 3.40.850.10; Kinesin motor domain; 1.
DR Gene3D; 1.20.120.720; Myosin VI head, motor domain, U50 subdomain; 1.
DR Gene3D; 1.25.40.530; MyTH4 domain; 3.
DR Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 2.
DR Gene3D; 2.30.30.40; SH3 Domains; 1.
DR InterPro; IPR019749; Band_41_domain.
DR InterPro; IPR014352; FERM/acyl-CoA-bd_prot_sf.
DR InterPro; IPR035963; FERM_2.
DR InterPro; IPR019748; FERM_central.
DR InterPro; IPR000299; FERM_domain.
DR InterPro; IPR000048; IQ_motif_EF-hand-BS.
DR InterPro; IPR036961; Kinesin_motor_dom_sf.
DR InterPro; IPR001609; Myosin_head_motor_dom.
DR InterPro; IPR041793; MyoVII_FERM_C1.
DR InterPro; IPR041794; MyoVII_FERM_C2.
DR InterPro; IPR036106; MYSc_Myo7.
DR InterPro; IPR000857; MyTH4_dom.
DR InterPro; IPR038185; MyTH4_dom_sf.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR011993; PH-like_dom_sf.
DR InterPro; IPR036028; SH3-like_dom_sf.
DR InterPro; IPR001452; SH3_domain.
DR InterPro; IPR029071; Ubiquitin-like_domsf.
DR PANTHER; PTHR22692; MYOSIN VII, XV; 1.
DR PANTHER; PTHR22692:SF34; MYOSIN VIIA; 1.
DR Pfam; PF00373; FERM_M; 2.
DR Pfam; PF00612; IQ; 3.
DR Pfam; PF00063; Myosin_head; 1.
DR Pfam; PF00784; MyTH4; 2.
DR PRINTS; PR00193; MYOSINHEAVY.
DR SMART; SM00295; B41; 2.
DR SMART; SM00015; IQ; 4.
DR SMART; SM00242; MYSc; 1.
DR SMART; SM00139; MyTH4; 2.
DR SMART; SM00326; SH3; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 2.
DR SUPFAM; SSF50729; PH domain-like; 1.
DR SUPFAM; SSF47031; Second domain of FERM; 2.
DR SUPFAM; SSF50044; SH3-domain; 1.
DR SUPFAM; SSF54236; Ubiquitin-like; 2.
DR PROSITE; PS50057; FERM_3; 2.
DR PROSITE; PS50096; IQ; 4.
DR PROSITE; PS51456; MYOSIN_MOTOR; 1.
DR PROSITE; PS51016; MYTH4; 2.
DR PROSITE; PS50002; SH3; 1.
PE 3: Inferred from homology;
KW Actin-binding {ECO:0000256|ARBA:ARBA00023203, ECO:0000256|PROSITE-
KW ProRule:PRU00782};
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|PROSITE-
KW ProRule:PRU00782};
KW Motor protein {ECO:0000256|ARBA:ARBA00023175, ECO:0000256|PROSITE-
KW ProRule:PRU00782};
KW Myosin {ECO:0000256|ARBA:ARBA00023123, ECO:0000256|PROSITE-
KW ProRule:PRU00782};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741, ECO:0000256|PROSITE-
KW ProRule:PRU00782}; Reference proteome {ECO:0000313|Proteomes:UP000087266};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW SH3 domain {ECO:0000256|ARBA:ARBA00022443, ECO:0000256|PROSITE-
KW ProRule:PRU00192}.
FT DOMAIN 65..747
FT /note="Myosin motor"
FT /evidence="ECO:0000259|PROSITE:PS51456"
FT DOMAIN 1024..1264
FT /note="MyTH4"
FT /evidence="ECO:0000259|PROSITE:PS51016"
FT DOMAIN 1269..1578
FT /note="FERM"
FT /evidence="ECO:0000259|PROSITE:PS50057"
FT DOMAIN 1576..1646
FT /note="SH3"
FT /evidence="ECO:0000259|PROSITE:PS50002"
FT DOMAIN 1721..1870
FT /note="MyTH4"
FT /evidence="ECO:0000259|PROSITE:PS51016"
FT DOMAIN 1876..2179
FT /note="FERM"
FT /evidence="ECO:0000259|PROSITE:PS50057"
FT REGION 624..646
FT /note="Actin-binding"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00782"
FT REGION 896..941
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT BINDING 164..171
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00782"
SQ SEQUENCE 2190 AA; 251774 MW; 6B72E57DCC7F6436 CRC64;
MVILQQGDYV WLDLKTGREF DVPVGAVLKL CDSGQIQVLD DEGREHWISP QNATNIKPMH
PTSIHGVEDM IRLGDLNEAG ILRNLLIRYN ERVIYTNCGG RTYTGSILVA VNPYQLLPIY
TPDQIRLYTN KKIGEMPPHI FAIADNCYFN MQRNNKDQCC IISGESGAGK TESTKLILQF
LAAISGQHSW IEQQVLEANP ILEAFGNAKT IRNDNSSRFG KYIDIHFNKR GAIEGAKIEQ
YLLEKSRVCR QAADERNYHI FYCMLRGMAP ELKTKLGLGL ATDYSYLTMG KCTKCDGRDD
LKDYSSILSA MKVLMFTETE NWEISKLLAA ILHMGNLRYE AHTYDNLDAC VVVRSPDLST
AASLMEVDPK DVMSCLTTRT LITRGESVST PLSMEQGLDV RNAFVKGIYG RLFVWIVDKI
NAAIFRPPSC ESKIVRRSIG LLDIFGFENF TVNSFEQLCI NFANENLQQF FVRHVFKLEQ
EEYNLEDINW QHIEFTDNQD ALDMIANKPM NIISLIDEES KFPKGTDATM LYKINSQHKL
NTNYHPPKNT YMTQFGIQHF AGVVHYETRG FLEKNRDSLH TDIIQLVHSS KNKFIKQIFQ
ADVAMGVETR KRSPTLSSQF KRSLELLMRT LNACQPFFVR CIKPNELKKP MLFDRELCVR
QLRYSGMMET IRIRRAGYPI RYTFGEFVDR YRVLMPGVKP ANRQEDLRGT CQKIVEAVLG
RDDDWQIGKT KIFLKDHHDM QLEIERDKAI TDKVILIQKA VRGMKERTNF LRVRRSVTLI
QKTWRGYRCR KDYSAMRVGF LRLQALYRSR KLFVTYRLAK TRVTQIQARC RGFMVRRSFW
RQLHAVITIQ AYARGMIARR VTQRLRAEHR RRQEAEGQRL AEEERLMNQM TARRARAEAE
RSHQERLAEL TRQEEQREKE AREEARRKKE LVEQVERERQ QPVDHSDMVD QMFGFLGNTG
ALPNLEGQGP AGFEDLEVAP RAEGEEEDLD EALPLPDDEE EDLSEYKFSK FAATYFQGTT
THTYVRRPLK QPLLFHEDEG DQLAALAVWI TVLRFMGDLP EPKYHIAISD GSEKIPVMTK
IYETLGKRTY KRELQELQTV EGENSSIEGG GGQKKNSVRH KLVSLTLKRK SKITEEVTRR
LTDGDYSLQG NSMLEDRPTS NLEKLHFIIG NGILRPALRD EIYCQICKQL TQNPSKSSHA
RGWILLSLCA GCFAPSEKFV KYLRTFMTSG PPGYAPYCEE RLRRTFVNRT RTQPPSWLEL
QATKSKKPIM LPVTFMDGTT KTLLTDSATT ASELCNALAD KISLQDRFGF SLYIALFDKV
SSLGSSSDHV MDAVSQCEQY AKEQGAQERN APWRLFFRKE IFTPWHNPGE DSVATNLIYQ
QTVRGVKFGE YRCERDEDLA ELASQQYYID YGSGILQERL LNLIPSYIPD REISSAKTND
KWAQLVIAAH KKGVYTQKRL DPQRVKEDVV DFARFKWPLL FSRFYEAFKF SGPSLPKNDV
IVAVNWTGVY FVDEQEQVLL ELSFPEITNV SSSRGGKLQG QSFSLATIKG DEYTFTSNNA
EDIRDLVVTF LEGLRKRSKF VVALLDCPNP AGGEDSTFLS FSKGDLILLD EHCGEQVMTS
GWAHGVNDRT KQQGDFPADC VYVLPTVTRP QYDIVALVTM TPDQRRESIN LSQLALAESE
DKVKPYTLEE FSYDYFRSPP KSTLSRVMIT KGRGKERLWC CAREPLKQPL LKKVLAHEEL
SQEAQLAFIA LLKYMGDYPS KRARSVNELT DQIFEGALKA EPLKDEIYCQ ILKQLTENHI
KYSEEKGWEL LWLCAGLFPP SNILLPHVQK FLQAKKHHPL APDCMQRLQK ALRNGSRKYP
PHLVEVEAIQ HKTTQIFHKV YFPDDTDEAF EVESSTKAKD FCLNISGRLL LKSSEGFSLF
VKITDKVISV PEGDFFFDFV RHLTDWIKKA RPAKDGVVPS LTYQVFFMKK LWTNTIPGKD
SMADYIFHYY QELPKYLRGY HQCSREEVFQ LGALIYRVKF EEDKSQFPNI PKMLKELIPQ
DQIRHLSPDD WKRSIVAFFN KQSGKTREEA KLSFLKAIFK WPTFGSAFFE VKQTSDPNFP
EILLIAINKH GVSLIDPKSK DILTTHPFTK ISNWSSGNTY FHITIGNLVR GTKLLCETSL
GYKMDDLLTS YISQMLTTMT KQRGSRGNIK
//
