ID A0A1S3RNW5_SALSA Unreviewed; 919 AA.
AC A0A1S3RNW5;
DT 12-APR-2017, integrated into UniProtKB/TrEMBL.
DT 12-APR-2017, sequence version 1.
DT 27-MAR-2024, entry version 31.
DE SubName: Full=SH3 and PX domain-containing protein 2B-like isoform X3 {ECO:0000313|RefSeq:XP_014053507.1};
GN Name=LOC106603845 {ECO:0000313|RefSeq:XP_014053507.1};
OS Salmo salar (Atlantic salmon).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Protacanthopterygii; Salmoniformes;
OC Salmonidae; Salmoninae; Salmo.
OX NCBI_TaxID=8030 {ECO:0000313|Proteomes:UP000087266, ECO:0000313|RefSeq:XP_014053507.1};
RN [1] {ECO:0000313|RefSeq:XP_014053507.1}
RP IDENTIFICATION.
RC TISSUE=Muscle {ECO:0000313|RefSeq:XP_014053507.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
CC -!- SIMILARITY: Belongs to the SH3PXD2 family.
CC {ECO:0000256|ARBA:ARBA00009628}.
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DR RefSeq; XP_014053507.1; XM_014198032.1.
DR AlphaFoldDB; A0A1S3RNW5; -.
DR STRING; 8030.ENSSSAP00000103848; -.
DR PaxDb; 8030-ENSSSAP00000103848; -.
DR GeneID; 106603845; -.
DR OrthoDB; 2910367at2759; -.
DR Proteomes; UP000087266; Chromosome ssa04.
DR Bgee; ENSSSAG00000075758; Expressed in nose and 14 other cell types or tissues.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0035091; F:phosphatidylinositol binding; IEA:InterPro.
DR CDD; cd06888; PX_FISH; 1.
DR Gene3D; 3.30.1520.10; Phox-like domain; 1.
DR Gene3D; 2.30.30.40; SH3 Domains; 4.
DR InterPro; IPR001683; PX_dom.
DR InterPro; IPR036871; PX_dom_sf.
DR InterPro; IPR036028; SH3-like_dom_sf.
DR InterPro; IPR001452; SH3_domain.
DR InterPro; IPR037961; SH3PXD2_PX.
DR PANTHER; PTHR15706:SF2; BUD EMERGENCE PROTEIN 1; 1.
DR PANTHER; PTHR15706; SH3 MULTIPLE DOMAIN; 1.
DR Pfam; PF00787; PX; 1.
DR Pfam; PF00018; SH3_1; 4.
DR SMART; SM00312; PX; 1.
DR SMART; SM00326; SH3; 4.
DR SUPFAM; SSF64268; PX domain; 1.
DR SUPFAM; SSF50044; SH3-domain; 4.
DR PROSITE; PS50195; PX; 1.
DR PROSITE; PS50002; SH3; 4.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000087266};
KW SH3 domain {ECO:0000256|ARBA:ARBA00022443, ECO:0000256|PROSITE-
KW ProRule:PRU00192}.
FT DOMAIN 4..128
FT /note="PX"
FT /evidence="ECO:0000259|PROSITE:PS50195"
FT DOMAIN 150..209
FT /note="SH3"
FT /evidence="ECO:0000259|PROSITE:PS50002"
FT DOMAIN 218..277
FT /note="SH3"
FT /evidence="ECO:0000259|PROSITE:PS50002"
FT DOMAIN 354..413
FT /note="SH3"
FT /evidence="ECO:0000259|PROSITE:PS50002"
FT DOMAIN 858..919
FT /note="SH3"
FT /evidence="ECO:0000259|PROSITE:PS50002"
FT REGION 289..354
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 437..572
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 593..856
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 303..320
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 500..527
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 553..572
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 663..681
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 683..724
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 768..787
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 801..822
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 823..856
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 919 AA; 102241 MW; 8EA0F412FDF4C28B CRC64;
MARRTVHEVT VQDVQKRRNP NKHYVYIIKV SWSDGSTEVI FRRYSKFFDL QMELLDKFPV
EGGQKDPKRR IIPFLPGKIL FRRSHIRDVA MKRLRPINEY CRALIQLPVY ISQCEEVRVF
FETRPEDLNP PKEELIGKKK SGDSSAGDPL LLDQYVAVTD YEKQESSEIS LHVGQTVEVI
EKNESGWWFV SSDEAQGWVP ATCLEAQDDP DDFSLPGEEE ETYTVIYPYA ARDQDEIDLE
SGMTVEVIQK NLEGWWKIRY QGQEGWAPAS YLKKADILSQ KLAAGHASTN DLDGFSKQQN
QAKESKGDNK DQKDKGFSPF AKQHKQGARQ RPPPRRDLTI PRGQNLPKPP TPPQVEEEFY
TIADFQTTIP DGISFQAGVK VEVIEKNSSG WWYIQIEDKE GWAPITFIDK YKKTSVTPRP
NFLAPLPNEM AQLKLEDGTA SGTGQEDSWS KPLPDEPTAS SESGARPKLR DWKSSASKGA
SAFSGPLPPA PSAPPAEEKP ALPPRRESIN KSLDIEITVE KPRPDLSKPM PPKPQAPGVI
MPLLTPKAAP FKPDKPPEPK REVANKPLHL KNEMGLECGH KVSAKEVKKF NLKPVAKQPS
KPKFDPPEEK PEVAGLALFM KPKPIVRPKP VPAAKPEPPA ENKLDITNLR SKLKPSKPVE
PGSGSAEPSQ QNGTAANNAP SNVLPKMPPP NLPPNNALPK MPPPNNVLPK MPRPSSPPIN
ALPKMPLAPN ALYNGKATDE PKFPHKQQNG HGQVSPDKCA VSPHKEPPGR PAVLPRRPPP
PKKTPEPSSP TETKAPLKEL PDTKPAPPQL SRPPPPKPKA FVLPPPKDKE KVVPKPLLKS
EKPGPPRDKL PPLIKDPSKE ELFLAVADFE GDDQTASFKE GTMFQVMERN SSGWWFCKNL
GEGPMKEGWI PSNYLTKKP
//
