ID A0A1S3RTD6_SALSA Unreviewed; 172 AA.
AC A0A1S3RTD6;
DT 12-APR-2017, integrated into UniProtKB/TrEMBL.
DT 12-APR-2017, sequence version 1.
DT 27-MAR-2024, entry version 25.
DE RecName: Full=N-acetylglucosaminyldiphosphodolichol N-acetylglucosaminyltransferase {ECO:0000256|ARBA:ARBA00012614};
DE EC=2.4.1.141 {ECO:0000256|ARBA:ARBA00012614};
GN Name=LOC106604701 {ECO:0000313|RefSeq:XP_014055097.1};
OS Salmo salar (Atlantic salmon).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Protacanthopterygii; Salmoniformes;
OC Salmonidae; Salmoninae; Salmo.
OX NCBI_TaxID=8030 {ECO:0000313|Proteomes:UP000087266, ECO:0000313|RefSeq:XP_014055097.1};
RN [1] {ECO:0000313|RefSeq:XP_014055097.1}
RP IDENTIFICATION.
RC TISSUE=Muscle {ECO:0000313|RefSeq:XP_014055097.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=N-acetyl-alpha-D-glucosaminyl-diphosphodolichol + UDP-N-
CC acetyl-alpha-D-glucosamine = H(+) + N,N'-diacetylchitobiosyl
CC diphosphodolichol + UDP; Xref=Rhea:RHEA:23380, Rhea:RHEA-COMP:9519,
CC Rhea:RHEA-COMP:9520, ChEBI:CHEBI:15378, ChEBI:CHEBI:57269,
CC ChEBI:CHEBI:57705, ChEBI:CHEBI:58223, ChEBI:CHEBI:58427;
CC EC=2.4.1.141; Evidence={ECO:0000256|ARBA:ARBA00000601};
CC -!- SIMILARITY: Belongs to the glycosyltransferase 28 family.
CC {ECO:0000256|ARBA:ARBA00006962}.
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DR RefSeq; XP_014055097.1; XM_014199622.1.
DR AlphaFoldDB; A0A1S3RTD6; -.
DR STRING; 8030.ENSSSAP00000031591; -.
DR PaxDb; 8030-ENSSSAP00000031591; -.
DR KEGG; sasa:106604701; -.
DR Proteomes; UP000087266; Chromosome ssa05.
DR GO; GO:0004577; F:N-acetylglucosaminyldiphosphodolichol N-acetylglucosaminyltransferase activity; IEA:UniProtKB-EC.
DR GO; GO:0006488; P:dolichol-linked oligosaccharide biosynthetic process; IEA:InterPro.
DR Gene3D; 3.40.50.2000; Glycogen Phosphorylase B; 1.
DR InterPro; IPR039042; Alg13-like.
DR InterPro; IPR007235; Glyco_trans_28_C.
DR PANTHER; PTHR12867; GLYCOSYL TRANSFERASE-RELATED; 1.
DR PANTHER; PTHR12867:SF6; N-ACETYLGLUCOSAMINYLDIPHOSPHODOLICHOL N-ACETYLGLUCOSAMINYLTRANSFERASE; 1.
DR Pfam; PF04101; Glyco_tran_28_C; 1.
DR SUPFAM; SSF53756; UDP-Glycosyltransferase/glycogen phosphorylase; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000087266};
KW Transferase {ECO:0000313|RefSeq:XP_014055097.1}.
FT DOMAIN 12..150
FT /note="Glycosyl transferase family 28 C-terminal"
FT /evidence="ECO:0000259|Pfam:PF04101"
SQ SEQUENCE 172 AA; 19242 MW; 94CFA2389D79F135 CRC64;
MTLVTCVTMK RVFVTVGTTS FDDLIERVTS PEAVQVLKGR GYQHLVLQVR RSFIFPDSDG
CHNLTLEAFK FKDSTAEDVK RADLVITHAR AGSCLETLGA GKPLLVVFND KLMDIHQLEL
AKQLHQDSYL LYFTASNLTE TLRTMDLSVL SPFLPRQPNN IANFLDKALG VQ
//
