ID A0A1S3RTJ9_SALSA Unreviewed; 877 AA.
AC A0A1S3RTJ9;
DT 12-APR-2017, integrated into UniProtKB/TrEMBL.
DT 12-APR-2017, sequence version 1.
DT 27-MAR-2024, entry version 30.
DE SubName: Full=Disks large homolog 3-like isoform X6 {ECO:0000313|RefSeq:XP_014055162.1};
GN Name=LOC106604729 {ECO:0000313|RefSeq:XP_014055162.1};
OS Salmo salar (Atlantic salmon).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Protacanthopterygii; Salmoniformes;
OC Salmonidae; Salmoninae; Salmo.
OX NCBI_TaxID=8030 {ECO:0000313|Proteomes:UP000087266, ECO:0000313|RefSeq:XP_014055162.1};
RN [1] {ECO:0000313|RefSeq:XP_014055162.1}
RP IDENTIFICATION.
RC TISSUE=Muscle {ECO:0000313|RefSeq:XP_014055162.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
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DR RefSeq; XP_014055162.1; XM_014199687.1.
DR AlphaFoldDB; A0A1S3RTJ9; -.
DR GeneID; 106604729; -.
DR OrthoDB; 2879721at2759; -.
DR Proteomes; UP000087266; Chromosome ssa05.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0031594; C:neuromuscular junction; IEA:InterPro.
DR GO; GO:0043005; C:neuron projection; IEA:InterPro.
DR GO; GO:0019900; F:kinase binding; IEA:InterPro.
DR GO; GO:0007268; P:chemical synaptic transmission; IEA:InterPro.
DR CDD; cd00071; GMPK; 1.
DR CDD; cd00992; PDZ_signaling; 3.
DR CDD; cd12029; SH3_DLG3; 1.
DR Gene3D; 2.30.42.10; -; 3.
DR Gene3D; 3.30.63.10; Guanylate Kinase phosphate binding domain; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 2.30.30.40; SH3 Domains; 2.
DR InterPro; IPR019583; DLG1-4_PDZ_assoc.
DR InterPro; IPR016313; DLG1-like.
DR InterPro; IPR019590; DLG1_PEST_dom.
DR InterPro; IPR035763; DLG3_SH3.
DR InterPro; IPR008145; GK/Ca_channel_bsu.
DR InterPro; IPR008144; Guanylate_kin-like_dom.
DR InterPro; IPR020590; Guanylate_kinase_CS.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR001478; PDZ.
DR InterPro; IPR036034; PDZ_sf.
DR InterPro; IPR036028; SH3-like_dom_sf.
DR InterPro; IPR001452; SH3_domain.
DR PANTHER; PTHR23119; DISCS LARGE; 1.
DR PANTHER; PTHR23119:SF28; DISKS LARGE HOMOLOG 3; 1.
DR Pfam; PF00625; Guanylate_kin; 1.
DR Pfam; PF10608; MAGUK_N_PEST; 1.
DR Pfam; PF00595; PDZ; 3.
DR Pfam; PF10600; PDZ_assoc; 1.
DR Pfam; PF00018; SH3_1; 1.
DR PIRSF; PIRSF001741; MAGUK_DLGH; 1.
DR SMART; SM00072; GuKc; 1.
DR SMART; SM01277; MAGUK_N_PEST; 1.
DR SMART; SM00228; PDZ; 3.
DR SMART; SM00326; SH3; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF50156; PDZ domain-like; 3.
DR SUPFAM; SSF50044; SH3-domain; 1.
DR PROSITE; PS00856; GUANYLATE_KINASE_1; 1.
DR PROSITE; PS50052; GUANYLATE_KINASE_2; 1.
DR PROSITE; PS50106; PDZ; 3.
DR PROSITE; PS50002; SH3; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|ARBA:ARBA00023136};
KW Reference proteome {ECO:0000313|Proteomes:UP000087266};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW SH3 domain {ECO:0000256|ARBA:ARBA00022443, ECO:0000256|PROSITE-
KW ProRule:PRU00192}.
FT DOMAIN 155..242
FT /note="PDZ"
FT /evidence="ECO:0000259|PROSITE:PS50106"
FT DOMAIN 250..337
FT /note="PDZ"
FT /evidence="ECO:0000259|PROSITE:PS50106"
FT DOMAIN 432..513
FT /note="PDZ"
FT /evidence="ECO:0000259|PROSITE:PS50106"
FT DOMAIN 547..617
FT /note="SH3"
FT /evidence="ECO:0000259|PROSITE:PS50002"
FT DOMAIN 687..862
FT /note="Guanylate kinase-like"
FT /evidence="ECO:0000259|PROSITE:PS50052"
FT REGION 41..109
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 877 AA; 96058 MW; 89DADCB5DF63B45C CRC64;
MHKHHHCCKC PECYEVTRMA ALRRMDAPQY QEWQTEPYGY PAGYGPGGGQ TLPQPPASGG
GGGGMGGGGG TLGRSKGKMM SSGGPGGPNP KLQSKGGPKV NGNTAGGQAG WWPECTCSNR
EWYDQANPPP VIVNADSLDA GPYVNGSDGM FKYEEIILER GNSGLGFSIA GGMDNPHIPD
DPGIFITKII PGGAAAMDGR LGVNDCVLRV NEVDVSEVVH SRAVEALKEA GPVVRLLVRR
RQAPPETILE INLLKGPKGL GFSIAGGIGN QHIPGDNSIY ITKIIEGGAA QKDGRLQTGD
RLLAVNNIIL QDVRHEEAVA ALKNTSDMVY LKVAKPGPVH LNDMYAPPDY SSSLALPALP
PAFPTMVDNH ISHNSGMAYM GAMEPKPVYS QPPQVTPSRY SPDPRHMLGE EDFTSPALRP
DAVALFGREP RKVLLHKGST GLGFNIVGGE DGEGIFVSFI LAGGPADLSG ELRRGDRILS
VNGVNLRNAT HEQAAAALKR AGQTVTIIAQ YRPEEYSRFE SKIHDLREQM MNSSMSSGSG
SLRTSEKRSL YVRALFDYDR ARDSCLPSQG LSFSYGDILH VINASDDEWW QARLVTPHGE
SEQIGVIPSK KRVEKKERAR LKTVKFHART GMIDSNRDFP GLSDDFYGSK SLKCLTSNTS
DSESSSKGQE DTILSYEPVI RQEIHYTRPV IILGPMKDRV NDDLISEFPH KFGSCVPHTT
RPRRENEMDG QDYHFVGSRE QMEKDIQDNK FIEAGQFNEN LYGTSILSVR AVAERGKHCI
LDVSGNAIKR LQQAQLYSIA IFIKPKSIET LMEMNKRQTF EQSNKIFDKA IKLEQEFGEF
FTAIVQGDSL EEIYNKIKMI IEEQSGPYIW IPSSEKL
//
