ID A0A1S3RU68_SALSA Unreviewed; 1053 AA.
AC A0A1S3RU68;
DT 12-APR-2017, integrated into UniProtKB/TrEMBL.
DT 12-APR-2017, sequence version 1.
DT 27-MAR-2024, entry version 27.
DE SubName: Full=Beta-klotho {ECO:0000313|RefSeq:XP_014055279.1};
GN Name=klb {ECO:0000313|RefSeq:XP_014055279.1};
OS Salmo salar (Atlantic salmon).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Protacanthopterygii; Salmoniformes;
OC Salmonidae; Salmoninae; Salmo.
OX NCBI_TaxID=8030 {ECO:0000313|Proteomes:UP000087266, ECO:0000313|RefSeq:XP_014055279.1};
RN [1] {ECO:0000313|RefSeq:XP_014055279.1}
RP IDENTIFICATION.
RC TISSUE=Muscle {ECO:0000313|RefSeq:XP_014055279.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
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DR RefSeq; XP_014055279.1; XM_014199804.1.
DR AlphaFoldDB; A0A1S3RU68; -.
DR STRING; 8030.ENSSSAP00000113764; -.
DR PaxDb; 8030-ENSSSAP00000113764; -.
DR GeneID; 106604780; -.
DR KEGG; sasa:106604780; -.
DR CTD; 152831; -.
DR OMA; DTQWFEP; -.
DR OrthoDB; 3373839at2759; -.
DR Proteomes; UP000087266; Chromosome ssa05.
DR Bgee; ENSSSAG00000079218; Expressed in digestive tract and 3 other cell types or tissues.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0004553; F:hydrolase activity, hydrolyzing O-glycosyl compounds; IEA:InterPro.
DR GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
DR Gene3D; 3.20.20.80; Glycosidases; 2.
DR InterPro; IPR001360; Glyco_hydro_1.
DR InterPro; IPR033132; Glyco_hydro_1_N_CS.
DR InterPro; IPR017853; Glycoside_hydrolase_SF.
DR PANTHER; PTHR10353:SF68; BETA-KLOTHO; 1.
DR PANTHER; PTHR10353; GLYCOSYL HYDROLASE; 1.
DR Pfam; PF00232; Glyco_hydro_1; 3.
DR SUPFAM; SSF51445; (Trans)glycosidases; 2.
DR PROSITE; PS00653; GLYCOSYL_HYDROL_F1_2; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000087266};
KW Signal {ECO:0000256|SAM:SignalP}; Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..16
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 17..1053
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5010186380"
FT TRANSMEM 986..1009
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT REGION 812..832
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1053 AA; 118949 MW; DE9F029A70743855 CRC64;
MATYLFSLFL TVIVWRGDFC SLGEGRRQWQ QPTTPEPFTQ SQSFFHGNFP PGFLWGTGTS
AFQTEGAWDC DSKGPSIWDH FTHSVPHRGD GGVADTASDG YNRWEEDVEA LGYLGVRSYA
FSLSWPRIFP DGVATGQSNK VAVEHYGRLL DRLLERGIEP VVTLFHWDLP QALQEHYGGW
RNDTLVGLFD AYAAFCFQTY GGRVRYWVTI HNPYLVAVQG YGTGVHAPGE TGDATAPFNV
AHNLIKAHAK AWHTYDTYFR PTQNGQVSIV LGSHWMEPKR DQVTPVNIEL CQQSMEAVLG
WFANPIFSDG DYPASMRSTH RGILPEFTPE EKHWVRGTAD FFSLSFGPNN LRLGRSLAHY
GQTVYPDMRR VLGWVRLEYG DLPVLVAEGG WFSAAAVERE DTDAIYLMKR FINQVLQAMV
FDGVRVFGYT AWSLVDGFEW NYGYSVRRGL FYLDFSQANR TRVPKTTAQF YRQVIKDNGF
LSDEITGEVK GRFPCDFHWG VADSSLQVNF YPFSPQFTDP HLYSWNLTGD GALRPVQGVN
LHIRGAQCTD YLAISGHVSL FKSTGASHYL FALNWSLILS QGDLSNVDTE ALRYYRCFLT
ELHKQGLEAV VTLYYPTNRV PLLGLPSPLH ASGGWLNQST VEAFQRYAAL CYRELGPWVS
YWITINEPNR LVDAYKIGEE QHLAAHNLLL AHARAFRLYE REYLSQQGGL VSLALHADWV
EPANPFLESH ATAAQRFLLF ELGRFLDPLL GGREGEGKSG RYPPEVRRYL EERARVMGLP
GSPLPHFTAR EKEELGGALG FIALNHFTTR LVSPRPQSPQ TAPPNPQQPP DHGCLLMSDH
TWASSGLEQA VVPWGLRRVL RWVKERYGGA LPVVVTASGV DDQAPVNDLL RQHYIRNYLQ
EALKARQLDG VNLKGFYVWK LQDRHVPEFG LFTSSHHKSR PKASIAAYRE IIERSGFPGN
NVTSSCRIID RRAVCSICAR ISENKLLLFF AACLLLTLAM LVGVVIVVVR GKRTRRRRRV
GLPVCPIPLG RKCQPWERVS LQSVTDRTRV VRR
//
