ID A0A1S3RUH3_SALSA Unreviewed; 972 AA.
AC A0A1S3RUH3;
DT 12-APR-2017, integrated into UniProtKB/TrEMBL.
DT 12-APR-2017, sequence version 1.
DT 27-MAR-2024, entry version 28.
DE SubName: Full=Thyroid hormone receptor-associated protein 3-like isoform X2 {ECO:0000313|RefSeq:XP_014055936.1};
GN Name=LOC106605126 {ECO:0000313|RefSeq:XP_014055936.1};
OS Salmo salar (Atlantic salmon).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Protacanthopterygii; Salmoniformes;
OC Salmonidae; Salmoninae; Salmo.
OX NCBI_TaxID=8030 {ECO:0000313|Proteomes:UP000087266, ECO:0000313|RefSeq:XP_014055936.1};
RN [1] {ECO:0000313|RefSeq:XP_014055936.1}
RP IDENTIFICATION.
RC TISSUE=Muscle {ECO:0000313|RefSeq:XP_014055936.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
CC Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC -!- SIMILARITY: Belongs to the BCLAF1/THRAP3 family.
CC {ECO:0000256|ARBA:ARBA00006481}.
CC -!- SIMILARITY: Belongs to the CASC3 family.
CC {ECO:0000256|ARBA:ARBA00009548}.
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DR RefSeq; XP_014055936.1; XM_014200461.1.
DR AlphaFoldDB; A0A1S3RUH3; -.
DR STRING; 8030.ENSSSAP00000030138; -.
DR PaxDb; 8030-ENSSSAP00000030138; -.
DR Ensembl; ENSSSAT00000246569; ENSSSAP00000125898; ENSSSAG00000039533.
DR GeneID; 106605126; -.
DR OMA; FKHITIS; -.
DR OrthoDB; 5323286at2759; -.
DR Proteomes; UP000087266; Chromosome ssa05.
DR Bgee; ENSSSAG00000039533; Expressed in muscle tissue and 13 other cell types or tissues.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0035145; C:exon-exon junction complex; IEA:InterPro.
DR GO; GO:0003729; F:mRNA binding; IEA:InterPro.
DR GO; GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.
DR GO; GO:0051028; P:mRNA transport; IEA:UniProtKB-KW.
DR GO; GO:0006417; P:regulation of translation; IEA:UniProtKB-KW.
DR GO; GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.
DR InterPro; IPR018545; Btz_dom.
DR InterPro; IPR029199; THRAP3_BCLAF1.
DR PANTHER; PTHR15268; THRAP3/BCLAF1; 1.
DR PANTHER; PTHR15268:SF16; THYROID HORMONE RECEPTOR-ASSOCIATED PROTEIN 3; 1.
DR Pfam; PF09405; Btz; 1.
DR Pfam; PF15440; THRAP3_BCLAF1; 1.
PE 3: Inferred from homology;
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW mRNA processing {ECO:0000256|ARBA:ARBA00022664};
KW mRNA splicing {ECO:0000256|ARBA:ARBA00023187};
KW mRNA transport {ECO:0000256|ARBA:ARBA00022816};
KW Nonsense-mediated mRNA decay {ECO:0000256|ARBA:ARBA00023161};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Receptor {ECO:0000313|RefSeq:XP_014055936.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000087266};
KW RNA-binding {ECO:0000256|ARBA:ARBA00022884};
KW Translation regulation {ECO:0000256|ARBA:ARBA00022845};
KW Transport {ECO:0000256|ARBA:ARBA00022448}.
FT DOMAIN 866..956
FT /note="Btz"
FT /evidence="ECO:0000259|Pfam:PF09405"
FT REGION 1..321
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 350..395
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 427..461
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 527..576
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 702..860
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 914..972
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 9..43
FT /note="Basic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 44..71
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 99..136
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 137..152
FT /note="Basic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 153..167
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 174..193
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 246..320
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 350..371
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 554..576
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 702..764
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 765..782
FT /note="Basic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 794..814
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 919..936
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 956..972
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 972 AA; 110298 MW; 5126ABBE62611BFC CRC64;
MSKATKSASK SRSHSRSRSS SRSRSRKHCY SSRSRTRSRS RSRSPSHNNR ERNYPREYQN
NNREFRGYHR GFRRPYYFRG RGRGYFPRGR FQRGGGRGYN NYRPNNWQNY RQHPQQQHPQ
QQQQQQQQQQ QPHSPRRGRS RTPKKRSGSP HSHSHSKYSD RSSSPRSRRS HRSSSSHSSS
PTRRSGSGST TQNSKDVKEE RSASKEVQKK GGGGGGGHGE PVEITGGSAG PDGGASGDKP
KADWQGVTDH SSSPKGSSPQ VRSAVIIGQG APASTQSSPS PKSTNANGPN YNGAPSWQIQ
TVDSSPSTKS PSQKSPTPVF SGFGFFSKDD NLAGDKAAIS SVFKRFLEEH NRKKKQSGWE
NGREMETNGG DVEWEKGNGM KATGGIFDRE PDKGENEKYK YREDFDDEGN VLLNHFLKAS
PFFSCDGEEE ELIPKPRPKV LRKEHDREDD ESPKPKSKVT LSARELFEER FGKWEDLAYL
QVAAKDDDLD AMAEEIYRSR KEEKAAAIAA ALAKREAIAG MLRGFSPENV SKDRRKEKAA
SSPSPTPAPR RNSDREMFIV RREDSPPRAS GKRRAEFSVR MDSLRDDVAS SSGVMVGERR
LSRDLVHPTK KEQEFRSVFQ HIQATQLQRS PSELFAQHIV TIVHYIKAQH FPSNGITLNE
RFAMYQRRAA QKEMMKPRKS PEIHRIIDVS LSAFKKHSHL FEGMKSSGDG SYKDEGKKMK
GDSMDLRLDI ERRKKYSTRE RDYKQDGGRD SGDSPEASRE RSVEKSSKHH KKSKKNKKKQ
SRSRSSSSSA ESHRGGDYPH KEPEFKDEGF NKARLGPRGD YGGPTERGRG RGGFQFRIRG
RGWNRGNYQG NNANGNPPNM GIPVHPKNED WDPEYTPKSR KYYLHDDREG ERKWVDNRGR
GNFLRGSRGR FIIRKASVGP PNNHTNNNSS PKWTHDKFQV NGGEEEDEPQ EEEAEQDHKD
QEKSEDMENT EQ
//
