ID A0A1S3RW82_SALSA Unreviewed; 1054 AA.
AC A0A1S3RW82;
DT 12-APR-2017, integrated into UniProtKB/TrEMBL.
DT 12-APR-2017, sequence version 1.
DT 27-MAR-2024, entry version 27.
DE SubName: Full=Echinoderm microtubule-associated protein-like 4 isoform X1 {ECO:0000313|RefSeq:XP_014056127.1};
GN Name=eml4 {ECO:0000313|RefSeq:XP_014056127.1};
OS Salmo salar (Atlantic salmon).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Protacanthopterygii; Salmoniformes;
OC Salmonidae; Salmoninae; Salmo.
OX NCBI_TaxID=8030 {ECO:0000313|Proteomes:UP000087266, ECO:0000313|RefSeq:XP_014056127.1};
RN [1] {ECO:0000313|RefSeq:XP_014056127.1}
RP IDENTIFICATION.
RC TISSUE=Muscle {ECO:0000313|RefSeq:XP_014056127.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the WD repeat EMAP family.
CC {ECO:0000256|ARBA:ARBA00006489}.
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DR RefSeq; XP_014056127.1; XM_014200652.1.
DR AlphaFoldDB; A0A1S3RW82; -.
DR STRING; 8030.ENSSSAP00000024674; -.
DR PaxDb; 8030-ENSSSAP00000024674; -.
DR GeneID; 106605231; -.
DR KEGG; sasa:106605231; -.
DR OMA; FTYNDSH; -.
DR OrthoDB; 2959353at2759; -.
DR Proteomes; UP000087266; Chromosome ssa01.
DR Bgee; ENSSSAG00000001809; Expressed in digestive tract and 15 other cell types or tissues.
DR CDD; cd21950; TD_EMAP4; 1.
DR Gene3D; 2.130.10.10; YVTN repeat-like/Quinoprotein amine dehydrogenase; 2.
DR InterPro; IPR005108; HELP.
DR InterPro; IPR011047; Quinoprotein_ADH-like_supfam.
DR InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR InterPro; IPR036322; WD40_repeat_dom_sf.
DR InterPro; IPR001680; WD40_rpt.
DR PANTHER; PTHR13720:SF11; ECHINODERM MICROTUBULE-ASSOCIATED PROTEIN-LIKE 4; 1.
DR PANTHER; PTHR13720; WD-40 REPEAT PROTEIN; 1.
DR Pfam; PF03451; HELP; 1.
DR Pfam; PF00400; WD40; 6.
DR SMART; SM00320; WD40; 9.
DR SUPFAM; SSF50998; Quinoprotein alcohol dehydrogenase-like; 1.
DR SUPFAM; SSF50978; WD40 repeat-like; 1.
DR PROSITE; PS50082; WD_REPEATS_2; 4.
DR PROSITE; PS50294; WD_REPEATS_REGION; 2.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Reference proteome {ECO:0000313|Proteomes:UP000087266};
KW WD repeat {ECO:0000256|PROSITE-ProRule:PRU00221}.
FT DOMAIN 282..350
FT /note="HELP"
FT /evidence="ECO:0000259|Pfam:PF03451"
FT REPEAT 559..591
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 642..674
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 771..804
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 884..918
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REGION 102..236
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 947..1054
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 35..69
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 137..160
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 171..194
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 217..236
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1007..1021
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1022..1037
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1054 AA; 115455 MW; F950B2B8BC033BAE CRC64;
MEEVSVSVAP ACNSTTTNTL LNNHCADDSI SAASASDVQD RLSSLELRVQ QQEDEITVMK
AALADVLRRL ALSEDTATTA KKQTSTKGQT PLREAYSMSC IANGSSSSRK PSHRDRDSST
VSVTRKDTFS SAAKSGQTAE RKKDKPQMEG IKEKEEGPSQ PNQANDKPSP ASPVQPSPSP
SISSHPPSPH PPQSQRQAPE SKGTSPAKRG HSAKRGTGME RSQSSTWESG EESRNKLVKA
ASTSKLLAKV VKNADKHKDP VISQAKMSTR EKNSQAEGDY IKMFMRGRPI TMFIPADVEN
YEDVRTELPP EKLKLEWVYG YRGRDCRANV YLLPTGESVY FIASVVVLFN YEERTQRHYL
GHTDCVKCLA IHPDKIRIAT GQIAGVDKDG RPLQPHVRVW DSVSLSTLQV IGLGTFERGV
GSLAFSKADS GTHLAVIDDC NDHMLTVWDW QKKSKIAEIK STNEVVLAVE FHPTDANTIV
TCGKSHIFFW TWAGTSLARK QGIFGKYEKP KFVQCLAFLN NGDILTGDSG GVMLIWSRST
VEPAPGKGPK GAYQISRQIK AHDGSVFTLC QMRNGTLLTG GGKDHKIILW DHDLNPERDI
EVPDQYGTIR AVAEGKGEQL LVGTSRNFVL RGTFNDGFQV EVQGHTDELW GLASHPFKDL
FLTCAQDRQV CLWNSVDHCL EWTRLLDEHG HCADFHPSGA VVAIGTHSGK WYALDAETRD
LVAIHTDGNE QLSVIRFSVD GTLLAVGSHD NFIYLYTVSD KGRKYTRYGK CIGHSSYITH
LDWSPDNKFI MSNSGDYEIL YWDIPNGCKY IRNRSECKDI DWATYTCVLG YHVFGVWPEG
SDGTDINALI RSHNRKVIAL ADDFCKVHLF QYPCARPKAP SHKYSAHSSH VTNVTFMHND
SHLVSTGGKD TSVMQWRLVE KTPSLVPSDS SLSLGEGLLH NSNPRATISA VPLTPTPTEP
AVTPIATPTP PSVLDLTSDP PAAIVTPPPP PTEPTTNGRQ ESSPGTPPPS GLTPPHSEST
PPPSHSTLSP KDSLDPSDDT ATPSDEGRPF TPPS
//
