ID   A0A1S3RW94_SALSA        Unreviewed;       980 AA.
AC   A0A1S3RW94;
DT   12-APR-2017, integrated into UniProtKB/TrEMBL.
DT   12-APR-2017, sequence version 1.
DT   27-MAR-2024, entry version 25.
DE   SubName: Full=Echinoderm microtubule-associated protein-like 4 isoform X3 {ECO:0000313|RefSeq:XP_014056142.1};
GN   Name=eml4 {ECO:0000313|RefSeq:XP_014056142.1};
OS   Salmo salar (Atlantic salmon).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Protacanthopterygii; Salmoniformes;
OC   Salmonidae; Salmoninae; Salmo.
OX   NCBI_TaxID=8030 {ECO:0000313|Proteomes:UP000087266, ECO:0000313|RefSeq:XP_014056142.1};
RN   [1] {ECO:0000313|RefSeq:XP_014056142.1}
RP   IDENTIFICATION.
RC   TISSUE=Muscle {ECO:0000313|RefSeq:XP_014056142.1};
RG   RefSeq;
RL   Submitted (NOV-2023) to UniProtKB.
CC   -!- SIMILARITY: Belongs to the WD repeat EMAP family.
CC       {ECO:0000256|ARBA:ARBA00006489}.
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DR   RefSeq; XP_014056142.1; XM_014200667.1.
DR   AlphaFoldDB; A0A1S3RW94; -.
DR   GeneID; 106605231; -.
DR   OrthoDB; 2959353at2759; -.
DR   Proteomes; UP000087266; Chromosome ssa01.
DR   CDD; cd21950; TD_EMAP4; 1.
DR   Gene3D; 2.130.10.10; YVTN repeat-like/Quinoprotein amine dehydrogenase; 2.
DR   InterPro; IPR005108; HELP.
DR   InterPro; IPR011047; Quinoprotein_ADH-like_supfam.
DR   InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR   InterPro; IPR036322; WD40_repeat_dom_sf.
DR   InterPro; IPR001680; WD40_rpt.
DR   PANTHER; PTHR13720:SF11; ECHINODERM MICROTUBULE-ASSOCIATED PROTEIN-LIKE 4; 1.
DR   PANTHER; PTHR13720; WD-40 REPEAT PROTEIN; 1.
DR   Pfam; PF03451; HELP; 1.
DR   Pfam; PF00400; WD40; 6.
DR   SMART; SM00320; WD40; 9.
DR   SUPFAM; SSF50998; Quinoprotein alcohol dehydrogenase-like; 1.
DR   SUPFAM; SSF50978; WD40 repeat-like; 1.
DR   PROSITE; PS50082; WD_REPEATS_2; 4.
DR   PROSITE; PS50294; WD_REPEATS_REGION; 2.
PE   3: Inferred from homology;
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Reference proteome {ECO:0000313|Proteomes:UP000087266};
KW   WD repeat {ECO:0000256|PROSITE-ProRule:PRU00221}.
FT   DOMAIN          208..276
FT                   /note="HELP"
FT                   /evidence="ECO:0000259|Pfam:PF03451"
FT   REPEAT          485..517
FT                   /note="WD"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT   REPEAT          568..600
FT                   /note="WD"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT   REPEAT          697..730
FT                   /note="WD"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT   REPEAT          810..844
FT                   /note="WD"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT   REGION          102..161
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          873..980
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          35..69
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COMPBIAS        143..161
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        933..947
FT                   /note="Pro residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        948..963
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   980 AA;  107657 MW;  299B10EA9627D12E CRC64;
     MEEVSVSVAP ACNSTTTNTL LNNHCADDSI SAASASDVQD RLSSLELRVQ QQEDEITVMK
     AALADVLRRL ALSEDTATTA KKQTSTKGQT PLREAYSMSC IANGSSSSRK PSHRDRDSST
     VSVTRKDTFS SAAKRGHSAK RGTGMERSQS STWESGEESR NKLVKAASTS KLLAKVVKNA
     DKHKDPVISQ AKMSTREKNS QAEGDYIKMF MRGRPITMFI PADVENYEDV RTELPPEKLK
     LEWVYGYRGR DCRANVYLLP TGESVYFIAS VVVLFNYEER TQRHYLGHTD CVKCLAIHPD
     KIRIATGQIA GVDKDGRPLQ PHVRVWDSVS LSTLQVIGLG TFERGVGSLA FSKADSGTHL
     AVIDDCNDHM LTVWDWQKKS KIAEIKSTNE VVLAVEFHPT DANTIVTCGK SHIFFWTWAG
     TSLARKQGIF GKYEKPKFVQ CLAFLNNGDI LTGDSGGVML IWSRSTVEPA PGKGPKGAYQ
     ISRQIKAHDG SVFTLCQMRN GTLLTGGGKD HKIILWDHDL NPERDIEVPD QYGTIRAVAE
     GKGEQLLVGT SRNFVLRGTF NDGFQVEVQG HTDELWGLAS HPFKDLFLTC AQDRQVCLWN
     SVDHCLEWTR LLDEHGHCAD FHPSGAVVAI GTHSGKWYAL DAETRDLVAI HTDGNEQLSV
     IRFSVDGTLL AVGSHDNFIY LYTVSDKGRK YTRYGKCIGH SSYITHLDWS PDNKFIMSNS
     GDYEILYWDI PNGCKYIRNR SECKDIDWAT YTCVLGYHVF GVWPEGSDGT DINALIRSHN
     RKVIALADDF CKVHLFQYPC ARPKAPSHKY SAHSSHVTNV TFMHNDSHLV STGGKDTSVM
     QWRLVEKTPS LVPSDSSLSL GEGLLHNSNP RATISAVPLT PTPTEPAVTP IATPTPPSVL
     DLTSDPPAAI VTPPPPPTEP TTNGRQESSP GTPPPSGLTP PHSESTPPPS HSTLSPKDSL
     DPSDDTATPS DEGRPFTPPS
//