ID A0A1S3RWR5_SALSA Unreviewed; 809 AA.
AC A0A1S3RWR5;
DT 12-APR-2017, integrated into UniProtKB/TrEMBL.
DT 12-APR-2017, sequence version 1.
DT 27-MAR-2024, entry version 26.
DE SubName: Full=Myotubularin-related protein 11-like isoform X2 {ECO:0000313|RefSeq:XP_014056239.1};
GN Name=LOC106605290 {ECO:0000313|RefSeq:XP_014056239.1};
OS Salmo salar (Atlantic salmon).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Protacanthopterygii; Salmoniformes;
OC Salmonidae; Salmoninae; Salmo.
OX NCBI_TaxID=8030 {ECO:0000313|Proteomes:UP000087266, ECO:0000313|RefSeq:XP_014056239.1};
RN [1] {ECO:0000313|RefSeq:XP_014056239.1}
RP IDENTIFICATION.
RC TISSUE=Muscle {ECO:0000313|RefSeq:XP_014056239.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the protein-tyrosine phosphatase family. Non-
CC receptor class myotubularin subfamily. {ECO:0000256|ARBA:ARBA00007471}.
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DR RefSeq; XP_014056239.1; XM_014200764.1.
DR AlphaFoldDB; A0A1S3RWR5; -.
DR Ensembl; ENSSSAT00000015618; ENSSSAP00000014695; ENSSSAG00000007191.
DR OrthoDB; 5474662at2759; -.
DR Proteomes; UP000087266; Chromosome ssa05.
DR Bgee; ENSSSAG00000007191; Expressed in zone of skin and 14 other cell types or tissues.
DR CDD; cd15790; PH-GRAM_MTMR11; 1.
DR CDD; cd14595; PTP-MTMR11; 1.
DR InterPro; IPR022587; MTMR12-like_C.
DR InterPro; IPR010569; Myotubularin-like_Pase_dom.
DR InterPro; IPR030564; Myotubularin_fam.
DR InterPro; IPR029021; Prot-tyrosine_phosphatase-like.
DR PANTHER; PTHR10807; MYOTUBULARIN-RELATED; 1.
DR PANTHER; PTHR10807:SF51; MYOTUBULARIN-RELATED PROTEIN 11; 1.
DR Pfam; PF12578; 3-PAP; 1.
DR Pfam; PF06602; Myotub-related; 2.
DR SUPFAM; SSF52799; (Phosphotyrosine protein) phosphatases II; 1.
DR SUPFAM; SSF50729; PH domain-like; 1.
DR PROSITE; PS51339; PPASE_MYOTUBULARIN; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000087266}.
FT DOMAIN 187..657
FT /note="Myotubularin phosphatase"
FT /evidence="ECO:0000259|PROSITE:PS51339"
FT REGION 695..809
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 695..729
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 751..776
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 809 AA; 90615 MW; 9FD3A0C86D0909DE CRC64;
MNERMLSHSG VNARGRDMFG LRCLPGECVL QRAVLVRKKL TAKEGGGWLS GTLFCTHFRV
AFVPQDSPKP DDNADPVLLG DHDVALASIE KVVAVGPSRT KLVTASSSLK FTPEELVLYC
RDLRVLCFLF DRLTPDTQAV EITYTIAKTY QPLKPGTVLS FQNAALGSVE MKQFLSNRRR
DAQMNWFDSL SDWEQELERT GTCGWRVSSV NDRFEMSTSL PKFNVVPQKV LDTELKKTFA
HFNEGRIPRW CWRHPRGSDL LRMASFQNNI YHEKDDIRNL ELILFGGQSL CVVVELGDEM
PSPTDIQLAH TRLRALCLGD ISTSVSVPDD KWLSTLESTH WLDYTRCCLR KAAEVACLLR
GGHLTVVLQE AEDRDMTCVV SSLVQVMCDP HCRTRAGFQG LVQKEWVMAG HRFLSRINYH
RDSDKEEAPV FLLFLDCVWQ LWVQYPSRFQ LTGDFLLALH DSFHLPLFSS FLANCHRERC
KRSQNLSQSY TPVNGWRDVV PRGSFPDSSD PPLPPVWDWA LQYSSQRRER FTQPVSLPAL
PQPLFNGNLN TNPEAHRLSD SAPGSVFLLS RGSFSCSANL LPWRSGGGSG VYRKSHRRGG
SSSENLPGLE RLLKAWALTE LPQGHTTIAG LQGPLDPYEP LLPLLLGPCL GVWRDCYLRG
ALHAQAFSHP ISSSTQHPVE RLAWEVQQLR DKLALASSTT NTVPAKTQEP RRTDSNLNQN
TNNSTFLFPA CRTPGPVVSR TMPPILNLQP RVPPASSSPL SRPGQRDSSK HTFLFGHPSS
SEARPDQRYF PAPNNNAKLP KSNGPSLGS
//
