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Database: UniProt
Entry: A0A1S3RXH6_SALSA
LinkDB: A0A1S3RXH6_SALSA
Original site: A0A1S3RXH6_SALSA 
ID   A0A1S3RXH6_SALSA        Unreviewed;       545 AA.
AC   A0A1S3RXH6;
DT   12-APR-2017, integrated into UniProtKB/TrEMBL.
DT   12-APR-2017, sequence version 1.
DT   05-JUN-2019, entry version 12.
DE   SubName: Full=growth factor receptor-bound protein 10-like isoform X1 {ECO:0000313|RefSeq:XP_014056514.1, ECO:0000313|RefSeq:XP_014056521.1, ECO:0000313|RefSeq:XP_014056522.1};
GN   Name=LOC106605415 {ECO:0000313|RefSeq:XP_014056514.1,
GN   ECO:0000313|RefSeq:XP_014056521.1, ECO:0000313|RefSeq:XP_014056522.1};
OS   Salmo salar (Atlantic salmon).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Protacanthopterygii;
OC   Salmoniformes; Salmonidae; Salmoninae; Salmo.
OX   NCBI_TaxID=8030 {ECO:0000313|Proteomes:UP000087266, ECO:0000313|RefSeq:XP_014056514.1};
RN   [1] {ECO:0000313|RefSeq:XP_014056514.1, ECO:0000313|RefSeq:XP_014056521.1, ECO:0000313|RefSeq:XP_014056522.1}
RP   IDENTIFICATION.
RC   TISSUE=Muscle {ECO:0000313|RefSeq:XP_014056514.1,
RC   ECO:0000313|RefSeq:XP_014056521.1};
RG   RefSeq;
RL   Submitted (JUN-2017) to UniProtKB.
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DR   RefSeq; XP_014056514.1; XM_014201039.1.
DR   RefSeq; XP_014056521.1; XM_014201046.1.
DR   RefSeq; XP_014056522.1; XM_014201047.1.
DR   GeneID; 106605415; -.
DR   KEGG; sasa:106605415; -.
DR   KO; K20064; -.
DR   OrthoDB; 497681at2759; -.
DR   Proteomes; UP000087266; Genome assembly.
DR   GO; GO:0005158; F:insulin receptor binding; IEA:InterPro.
DR   GO; GO:0005070; F:SH3/SH2 adaptor activity; IEA:InterPro.
DR   GO; GO:0046627; P:negative regulation of insulin receptor signaling pathway; IEA:InterPro.
DR   GO; GO:0007165; P:signal transduction; IEA:InterPro.
DR   CDD; cd01259; PH_APBB1IP; 1.
DR   CDD; cd10415; SH2_Grb10; 1.
DR   Gene3D; 2.30.29.30; -; 1.
DR   Gene3D; 3.30.505.10; -; 1.
DR   InterPro; IPR015042; BPS-dom.
DR   InterPro; IPR039664; GRB/APBB1IP.
DR   InterPro; IPR035036; Grb10.
DR   InterPro; IPR035037; Grb10_SH2.
DR   InterPro; IPR011993; PH-like_dom_sf.
DR   InterPro; IPR039665; PH_APBB1IP.
DR   InterPro; IPR001849; PH_domain.
DR   InterPro; IPR000159; RA_dom.
DR   InterPro; IPR000980; SH2.
DR   InterPro; IPR036860; SH2_dom_sf.
DR   InterPro; IPR029071; Ubiquitin-like_domsf.
DR   PANTHER; PTHR11243; PTHR11243; 1.
DR   PANTHER; PTHR11243:SF4; PTHR11243:SF4; 1.
DR   Pfam; PF08947; BPS; 1.
DR   Pfam; PF00169; PH; 1.
DR   Pfam; PF00788; RA; 1.
DR   Pfam; PF00017; SH2; 1.
DR   PRINTS; PR00401; SH2DOMAIN.
DR   SMART; SM00233; PH; 1.
DR   SMART; SM00314; RA; 1.
DR   SMART; SM00252; SH2; 1.
DR   SUPFAM; SSF54236; SSF54236; 1.
DR   SUPFAM; SSF55550; SSF55550; 1.
DR   PROSITE; PS50003; PH_DOMAIN; 1.
DR   PROSITE; PS50200; RA; 1.
DR   PROSITE; PS50001; SH2; 1.
PE   4: Predicted;
KW   Complete proteome {ECO:0000313|Proteomes:UP000087266};
KW   Receptor {ECO:0000313|RefSeq:XP_014056514.1,
KW   ECO:0000313|RefSeq:XP_014056521.1, ECO:0000313|RefSeq:XP_014056522.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000087266};
KW   SH2 domain {ECO:0000256|PROSITE-ProRule:PRU00191}.
FT   DOMAIN      117    201       Ras-associating. {ECO:0000259|PROSITE:
FT                                PS50200}.
FT   DOMAIN      243    351       PH. {ECO:0000259|PROSITE:PS50003}.
FT   DOMAIN      444    540       SH2. {ECO:0000259|PROSITE:PS50001}.
FT   REGION       27     66       Disordered. {ECO:0000256|MobiDB-lite:
FT                                A0A1S3RXH6}.
FT   COMPBIAS     42     64       Polar. {ECO:0000256|MobiDB-lite:
FT                                A0A1S3RXH6}.
SQ   SEQUENCE   545 AA;  62438 MW;  F9301CBD0CDA885D CRC64;
     MNSSFESLYS TCSSVQSESV PLLQHNGQVH VHRDHHRSAP MPPHTHTSNS ELQHSTTSPK
     QRLRRSQPMH ILAVRRLQEE EQQLRTSSLP AIPNPFPELS GSPVLSPGSL PPCQPSGTYI
     INIFSEDGMG KVVEIPADMT ARDLCQLLVY KSHCVDDNSW ALVEHHPLLG LERCLEDHEL
     VVQVQASMTS EGRFLFRKNY AKYEFFRNPL NFFPEHMVAW CQETNGAIPP SQLLQNFLNS
     SSCPEIQGFL YVKEMGRKSW KKLYVFLRRS GLYFSTKGTS KEPRHLQLLA DLEDSNVFTV
     TTGKKLHSAP TDYEFCIKPN KRTELKELRM LCTEDEQSRT SWMTAFRLFK YGIVLYQNYK
     IPQQRKTLSH FSTPVRSVSE NSLVAMDFSG RIGRVIDNPL EAQSAAMEEG NAWRKRSQRM
     NILGSPSPLH PCLLNSVIHR TQLWFHGRIT REESHRMIHQ QGQVDGLFLL RDSQSNPKAF
     VLTLCHHQKI KHFQILPCEE DGQIFFSLDD GSTKFTDLIQ LVEFYQLNRG VLPCKLKHPC
     TLVAL
//
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