ID A0A1S3RXR2_SALSA Unreviewed; 554 AA.
AC A0A1S3RXR2;
DT 12-APR-2017, integrated into UniProtKB/TrEMBL.
DT 12-APR-2017, sequence version 1.
DT 27-MAR-2024, entry version 31.
DE SubName: Full=Histone-lysine N-methyltransferase PRDM9-like {ECO:0000313|RefSeq:XP_014056682.1};
GN Name=LOC106605487 {ECO:0000313|RefSeq:XP_014056682.1};
OS Salmo salar (Atlantic salmon).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Protacanthopterygii; Salmoniformes;
OC Salmonidae; Salmoninae; Salmo.
OX NCBI_TaxID=8030 {ECO:0000313|Proteomes:UP000087266, ECO:0000313|RefSeq:XP_014056682.1};
RN [1] {ECO:0000313|RefSeq:XP_014056682.1}
RP IDENTIFICATION.
RC TISSUE=Muscle {ECO:0000313|RefSeq:XP_014056682.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
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DR RefSeq; XP_014056682.1; XM_014201207.1.
DR AlphaFoldDB; A0A1S3RXR2; -.
DR STRING; 8030.ENSSSAP00000052643; -.
DR PaxDb; 8030-ENSSSAP00000052643; -.
DR KEGG; sasa:106605487; -.
DR OMA; KRTWQRE; -.
DR OrthoDB; 2960873at2759; -.
DR Proteomes; UP000087266; Chromosome ssa05.
DR Bgee; ENSSSAG00000051935; Expressed in testis and 1 other cell type or tissue.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0042054; F:histone methyltransferase activity; IEA:InterPro.
DR GO; GO:0032259; P:methylation; IEA:UniProtKB-KW.
DR CDD; cd19193; PR-SET_PRDM7_9; 1.
DR Gene3D; 3.30.160.60; Classic Zinc Finger; 6.
DR Gene3D; 2.170.270.10; SET domain; 1.
DR InterPro; IPR044417; PRDM7_9_PR-SET.
DR InterPro; IPR001214; SET_dom.
DR InterPro; IPR046341; SET_dom_sf.
DR InterPro; IPR036236; Znf_C2H2_sf.
DR InterPro; IPR013087; Znf_C2H2_type.
DR PANTHER; PTHR16515; PR DOMAIN ZINC FINGER PROTEIN; 1.
DR PANTHER; PTHR16515:SF57; PR DOMAIN-CONTAINING PROTEIN 11; 1.
DR Pfam; PF21549; PRDM2_PR; 1.
DR Pfam; PF00096; zf-C2H2; 6.
DR SMART; SM00355; ZnF_C2H2; 7.
DR SUPFAM; SSF57667; beta-beta-alpha zinc fingers; 3.
DR SUPFAM; SSF82199; SET domain; 1.
DR PROSITE; PS50280; SET; 1.
DR PROSITE; PS00028; ZINC_FINGER_C2H2_1; 6.
DR PROSITE; PS50157; ZINC_FINGER_C2H2_2; 7.
PE 4: Predicted;
KW Metal-binding {ECO:0000256|PROSITE-ProRule:PRU00042};
KW Methyltransferase {ECO:0000256|ARBA:ARBA00022603};
KW Reference proteome {ECO:0000313|Proteomes:UP000087266};
KW S-adenosyl-L-methionine {ECO:0000256|ARBA:ARBA00022691};
KW Transferase {ECO:0000256|ARBA:ARBA00022679};
KW Zinc {ECO:0000256|PROSITE-ProRule:PRU00042};
KW Zinc-finger {ECO:0000256|PROSITE-ProRule:PRU00042}.
FT DOMAIN 167..281
FT /note="SET"
FT /evidence="ECO:0000259|PROSITE:PS50280"
FT DOMAIN 313..341
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 387..414
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 415..442
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 443..470
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 471..498
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 499..526
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 527..546
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT REGION 1..89
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 354..394
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 533..554
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 40..66
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 354..375
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 554 AA; 62284 MW; B3E9BD1ED8C3D4BD CRC64;
MGTEPPQPFL EELTEKVVFL RDGSTADTHS GEQEGLGDKE GQSEATSSTS GGETERSTQG
GGADTPALTQ RGTPLLHPKP STSGLSKREW LERQKALNTY KRGRNLRDRP RITYTEEEVP
KDDHYLYCED CKSFFMEECE LHGPAFFVPD IPVPLGAPDR ARLTLPSGLE VRTSGIPEAG
LGVFNQGNTV PAGAHYGPYE GEITDKDQAM ESGYSWVIYK SRHWDDYIDA GRDTHSNWMR
YVNCARSEEE QNLVAFQYRG GILYRCCKPI AVGEELLVWY GGEYARDLGI VFDYLWDKKS
SAKDVNVESF QIFSCSGCPL SFTSQIFLLK HIKRCHHDEY VRLLRSGEIR SENLMSSSSS
QHHGSTTGSF NPAPTRKQRE TDKPRPHRCS QCGKSFTTGR NLIIHQRIHT GEKPFHCSQC
GRSFSRSGPL KTHQRIHTGE KPFHCSQCGR SFSQSGDLKT HQRIHTGEKP FHCSQCGRSF
SQSGDLKTHQ RIHTGEKPFH CSQCGRSFSQ SGPLKTHQRI HTGEKPFHCS QCGRSFSQSG
NLKKHKCSKK SKEL
//
