ID A0A1S3S1U9_SALSA Unreviewed; 309 AA.
AC A0A1S3S1U9;
DT 12-APR-2017, integrated into UniProtKB/TrEMBL.
DT 12-APR-2017, sequence version 1.
DT 27-MAR-2024, entry version 32.
DE SubName: Full=Ventral anterior homeobox 1 {ECO:0000313|RefSeq:XP_014058267.1};
GN Name=vax1 {ECO:0000313|RefSeq:XP_014058267.1};
OS Salmo salar (Atlantic salmon).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Protacanthopterygii; Salmoniformes;
OC Salmonidae; Salmoninae; Salmo.
OX NCBI_TaxID=8030 {ECO:0000313|Proteomes:UP000087266, ECO:0000313|RefSeq:XP_014058267.1};
RN [1] {ECO:0000313|RefSeq:XP_014058267.1}
RP IDENTIFICATION.
RC TISSUE=Muscle {ECO:0000313|RefSeq:XP_014058267.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123,
CC ECO:0000256|PROSITE-ProRule:PRU00108, ECO:0000256|RuleBase:RU000682}.
CC -!- SIMILARITY: Belongs to the EMX homeobox family.
CC {ECO:0000256|ARBA:ARBA00007397}.
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DR RefSeq; XP_014058267.1; XM_014202792.1.
DR AlphaFoldDB; A0A1S3S1U9; -.
DR STRING; 8030.ENSSSAP00000004085; -.
DR PaxDb; 8030-ENSSSAP00000004085; -.
DR GeneID; 106606525; -.
DR KEGG; sasa:106606525; -.
DR OMA; GAMENCE; -.
DR OrthoDB; 903523at2759; -.
DR Proteomes; UP000087266; Chromosome ssa01.
DR Bgee; ENSSSAG00000002021; Expressed in brain and 1 other cell type or tissue.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0000981; F:DNA-binding transcription factor activity, RNA polymerase II-specific; IEA:InterPro.
DR CDD; cd00086; homeodomain; 1.
DR Gene3D; 1.10.10.60; Homeodomain-like; 1.
DR InterPro; IPR009057; Homeobox-like_sf.
DR InterPro; IPR017970; Homeobox_CS.
DR InterPro; IPR001356; Homeobox_dom.
DR InterPro; IPR000047; HTH_motif.
DR PANTHER; PTHR24339; HOMEOBOX PROTEIN EMX-RELATED; 1.
DR PANTHER; PTHR24339:SF32; VENTRAL ANTERIOR HOMEOBOX 1; 1.
DR Pfam; PF00046; Homeodomain; 1.
DR PRINTS; PR00031; HTHREPRESSR.
DR SMART; SM00389; HOX; 1.
DR SUPFAM; SSF46689; Homeodomain-like; 1.
DR PROSITE; PS00027; HOMEOBOX_1; 1.
DR PROSITE; PS50071; HOMEOBOX_2; 1.
PE 3: Inferred from homology;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125, ECO:0000256|PROSITE-
KW ProRule:PRU00108};
KW Homeobox {ECO:0000256|ARBA:ARBA00023155, ECO:0000256|PROSITE-
KW ProRule:PRU00108};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242, ECO:0000256|PROSITE-
KW ProRule:PRU00108}; Reference proteome {ECO:0000313|Proteomes:UP000087266};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT DOMAIN 90..150
FT /note="Homeobox"
FT /evidence="ECO:0000259|PROSITE:PS50071"
FT DNA_BIND 92..151
FT /note="Homeobox"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00108"
FT REGION 1..60
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 203..232
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 29..54
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 207..232
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 309 AA; 33541 MW; C77284EA60BF617E CRC64;
MEVRYNQETE PGMGPKNGLK DGKDSKDSQG NLSKTFLKDQ QESFSPSGMV ENCEKNRAST
GDPDYCRRIL VRDAKGSIRE IILPKGLDLD RPKRTRTSFT AEQLYRLEME FQRCQYVVGR
ERTELARQLN LSETQVKVWF QNRRTKQKKD QGKDSELRSV VSETAATCSV LRLLEQGRLL
TPPGLPGLLQ HCGNGTLSAA LRGPSMGMAS NGSSSSSGAS SGTAGGSPPL PIVTSSGTVA
GLQSSPSAHG LFSFPMPSLL GSVATRMSSN PLSMAGNLQE LSARYLSSSA FEPYSRTNGK
ESMDKNVFE
//
