ID A0A1S3S3M0_SALSA Unreviewed; 1267 AA.
AC A0A1S3S3M0;
DT 12-APR-2017, integrated into UniProtKB/TrEMBL.
DT 12-APR-2017, sequence version 1.
DT 27-MAR-2024, entry version 31.
DE SubName: Full=Caskin-2-like isoform X3 {ECO:0000313|RefSeq:XP_014058973.1};
GN Name=LOC106606974 {ECO:0000313|RefSeq:XP_014058973.1};
OS Salmo salar (Atlantic salmon).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Protacanthopterygii; Salmoniformes;
OC Salmonidae; Salmoninae; Salmo.
OX NCBI_TaxID=8030 {ECO:0000313|Proteomes:UP000087266, ECO:0000313|RefSeq:XP_014058973.1};
RN [1] {ECO:0000313|RefSeq:XP_014058973.1}
RP IDENTIFICATION.
RC TISSUE=Muscle {ECO:0000313|RefSeq:XP_014058973.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
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DR RefSeq; XP_014058973.1; XM_014203498.1.
DR AlphaFoldDB; A0A1S3S3M0; -.
DR OrthoDB; 25046at2759; -.
DR Proteomes; UP000087266; Chromosome ssa06.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR CDD; cd09497; SAM_caskin1_2_repeat1; 1.
DR CDD; cd09498; SAM_caskin1_2_repeat2; 1.
DR CDD; cd12063; SH3_Caskin2; 1.
DR Gene3D; 1.25.40.20; Ankyrin repeat-containing domain; 2.
DR Gene3D; 2.30.30.40; SH3 Domains; 1.
DR Gene3D; 1.10.150.50; Transcription Factor, Ets-1; 2.
DR InterPro; IPR033635; ANKS1/Caskin.
DR InterPro; IPR002110; Ankyrin_rpt.
DR InterPro; IPR036770; Ankyrin_rpt-contain_sf.
DR InterPro; IPR032232; Caskin1-CID.
DR InterPro; IPR035497; Caskin1/2_SAM_1.
DR InterPro; IPR035498; Caskin1/2_SAM_2.
DR InterPro; IPR035499; Caskin2_SH3.
DR InterPro; IPR032117; Caskin_C.
DR InterPro; IPR001660; SAM.
DR InterPro; IPR013761; SAM/pointed_sf.
DR InterPro; IPR036028; SH3-like_dom_sf.
DR InterPro; IPR001452; SH3_domain.
DR PANTHER; PTHR24174; ANKYRIN REPEAT AND STERILE ALPHA MOTIF DOMAIN-CONTAINING PROTEIN 1; 1.
DR PANTHER; PTHR24174:SF19; CASKIN-2-LIKE-RELATED; 1.
DR Pfam; PF12796; Ank_2; 2.
DR Pfam; PF16907; Caskin-Pro-rich; 1.
DR Pfam; PF16632; Caskin-tail; 1.
DR Pfam; PF16600; Caskin1-CID; 1.
DR Pfam; PF00536; SAM_1; 2.
DR Pfam; PF07653; SH3_2; 1.
DR PRINTS; PR01415; ANKYRIN.
DR SMART; SM00248; ANK; 5.
DR SMART; SM00454; SAM; 2.
DR SMART; SM00326; SH3; 1.
DR SUPFAM; SSF48403; Ankyrin repeat; 1.
DR SUPFAM; SSF47769; SAM/Pointed domain; 2.
DR SUPFAM; SSF50044; SH3-domain; 1.
DR PROSITE; PS50297; ANK_REP_REGION; 4.
DR PROSITE; PS50088; ANK_REPEAT; 4.
DR PROSITE; PS50105; SAM_DOMAIN; 2.
DR PROSITE; PS50002; SH3; 1.
PE 4: Predicted;
KW ANK repeat {ECO:0000256|PROSITE-ProRule:PRU00023};
KW Reference proteome {ECO:0000313|Proteomes:UP000087266};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW SH3 domain {ECO:0000256|ARBA:ARBA00022443, ECO:0000256|PROSITE-
KW ProRule:PRU00192}.
FT REPEAT 1..31
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 32..64
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 106..138
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 138..170
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT DOMAIN 199..265
FT /note="SH3"
FT /evidence="ECO:0000259|PROSITE:PS50002"
FT DOMAIN 428..491
FT /note="SAM"
FT /evidence="ECO:0000259|PROSITE:PS50105"
FT DOMAIN 497..561
FT /note="SAM"
FT /evidence="ECO:0000259|PROSITE:PS50105"
FT REGION 267..388
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 633..693
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 724..751
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 794..1087
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1101..1136
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1159..1180
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 269..312
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 324..369
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 636..687
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 734..751
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 811..841
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 955..977
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 981..995
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1040..1058
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1059..1087
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1112..1126
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1267 AA; 135361 MW; 571A3DBA4BF9CC6C CRC64;
MRPLHYAAWQ GKADSVLLLL RAGAGVNGVS QDGHIPLHLA AQYGHYDVSE MLLQHQSNPC
LINKTKKTPL DLACEFGRVK VAQLLLSSNM VVALLEGNSK EPADSGFNTP LHLAARNGHK
DIIRLLLKAG IDINRATKAG TALHEAALYG KTEVVRQLLE AGIDVNIRNT YNQTALDIVN
QFTTSHASKD IKQLLRDATG VLQVRALKDY WNIHDPTALN IRAGDVIMVL EQHVDGRWKG
HIHDSQRGTD RVGYFPPNIV EVISRRSGGT LSRHASLPTQ RHQLLSRAPL SSSLSSAPQT
DDSYTLYTPN NPHLALPHTI GLSANPGDRN SVGSTGSVGS TRSAGSGQST ESNTAPNGQH
QQTTALPDTA KPAPSAGDSG QPVPNKQPDL TAVVLGAPRR PMVNIQRPGE QQFVSPQFVR
PQQLLEGKDA EAIYQWLSDF QLEQYTGNFI TAGYDVPTIS RMTPEDLTAI GVTKPGHRKK
ISIEIGNLSI PEWLPEYIPA DLGEWLSTIG LPQYQRKLSE NGYDSISIVR DLTWEDLQEI
GITKLGHQKK MMLAVKKLCD IQRAILAAES GQGTLRRKPP GALHLVTIEP PDSASDCPSP
HTPKMLTFQD SELSAELQTA MSSHYQEGLA IKSAVGMSRS QESIDARSRG SGRSQDPPTA
SITPHSRSQE SLGSSSTSTS LSADSSPAKE RNIPEGWDQR SILQQQLPKQ VPLGAATVFK
YPAIPAKPKG PGSHSLGSSP QGSPAQRGFS YLHSHCGSTD LSYGSPTKPL AHTYHAMTLA
PPKKRSQSLT RYALSDGEPD EEDDDLAPPS STLESYATLT RRPGRSQLAG MQTTPVKYGT
VGRSQSFAVR ARKKGPPPAP PKRLSSVSSS PSVGSMENMA PSPGGVETDS PGSVRSIAAC
LEASTEGKSL SRPRLDLLQP EPLLPSLTPS GLEPREASAG MKRRVQSECV PAQTDIPDHD
PERGVKSDSE EEEPKAPGLD GSSSPHNSSS ECIPFAEEGN LTIKQRPKVG GPLRAESTVE
IPADKNGPTK TALEVPEFNL KESDTVKRRY KPKDHAGSSP TSDSEGQIES DSSPGSRAQS
QSCEEVSLVS LRISEASLEG LENLAGTGTP LKPPVSPKPH SSHRPPVTAP KPSRHSLAAA
TAIVPPTMTV NVVQSLAFSA PPSPTPSRCP TAPGLQSQAA QTGKPQICVV GPGPGVESGP
GLEVVQQQRL EQTSTSLEAA LQAVERKLTQ EDSTDGGANT VKSAGNILDD IGNMFDDLAD
QLDAMLD
//
