ID A0A1S3S5L8_SALSA Unreviewed; 1093 AA.
AC A0A1S3S5L8;
DT 12-APR-2017, integrated into UniProtKB/TrEMBL.
DT 12-APR-2017, sequence version 1.
DT 27-MAR-2024, entry version 30.
DE SubName: Full=Formin-like protein 1 {ECO:0000313|RefSeq:XP_014059635.1};
GN Name=LOC106607317 {ECO:0000313|RefSeq:XP_014059635.1};
OS Salmo salar (Atlantic salmon).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Protacanthopterygii; Salmoniformes;
OC Salmonidae; Salmoninae; Salmo.
OX NCBI_TaxID=8030 {ECO:0000313|Proteomes:UP000087266, ECO:0000313|RefSeq:XP_014059635.1};
RN [1] {ECO:0000313|RefSeq:XP_014059635.1}
RP IDENTIFICATION.
RC TISSUE=Muscle {ECO:0000313|RefSeq:XP_014059635.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the formin homology family.
CC {ECO:0000256|ARBA:ARBA00023449}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR RefSeq; XP_014059635.1; XM_014204160.1.
DR AlphaFoldDB; A0A1S3S5L8; -.
DR STRING; 8030.ENSSSAP00000012910; -.
DR PaxDb; 8030-ENSSSAP00000012910; -.
DR GeneID; 106607317; -.
DR KEGG; sasa:106607317; -.
DR OrthoDB; 471257at2759; -.
DR Proteomes; UP000087266; Chromosome ssa06.
DR GO; GO:0003779; F:actin binding; IEA:InterPro.
DR GO; GO:0031267; F:small GTPase binding; IEA:InterPro.
DR GO; GO:0030036; P:actin cytoskeleton organization; IEA:InterPro.
DR GO; GO:0022604; P:regulation of cell morphogenesis; IEA:InterPro.
DR Gene3D; 1.20.58.2220; Formin, FH2 domain; 1.
DR Gene3D; 1.25.10.10; Leucine-rich Repeat Variant; 2.
DR InterPro; IPR011989; ARM-like.
DR InterPro; IPR016024; ARM-type_fold.
DR InterPro; IPR014767; DAD_dom.
DR InterPro; IPR015425; FH2_Formin.
DR InterPro; IPR042201; FH2_Formin_sf.
DR InterPro; IPR010472; FH3_dom.
DR InterPro; IPR043592; FMNL_animal.
DR InterPro; IPR014768; GBD/FH3_dom.
DR InterPro; IPR010473; GTPase-bd.
DR PANTHER; PTHR45857; FORMIN-LIKE PROTEIN; 1.
DR PANTHER; PTHR45857:SF2; FORMIN-LIKE PROTEIN 1; 1.
DR Pfam; PF06367; Drf_FH3; 1.
DR Pfam; PF06371; Drf_GBD; 2.
DR Pfam; PF02181; FH2; 1.
DR SMART; SM01139; Drf_FH3; 1.
DR SMART; SM01140; Drf_GBD; 1.
DR SMART; SM00498; FH2; 1.
DR SUPFAM; SSF48371; ARM repeat; 1.
DR SUPFAM; SSF101447; Formin homology 2 domain (FH2 domain); 1.
DR PROSITE; PS51231; DAD; 1.
DR PROSITE; PS51444; FH2; 1.
DR PROSITE; PS51232; GBD_FH3; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Reference proteome {ECO:0000313|Proteomes:UP000087266}.
FT DOMAIN 43..478
FT /note="GBD/FH3"
FT /evidence="ECO:0000259|PROSITE:PS51232"
FT DOMAIN 639..1030
FT /note="FH2"
FT /evidence="ECO:0000259|PROSITE:PS51444"
FT DOMAIN 1060..1093
FT /note="DAD"
FT /evidence="ECO:0000259|PROSITE:PS51231"
FT REGION 1..47
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 175..207
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 466..499
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 543..640
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1011..1093
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 414..459
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 471..499
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 562..630
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1011..1041
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1049..1070
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1093 AA; 121596 MW; 28308BFCBA837425 CRC64;
MGNAAGGIEQ ADGREAKHSV GSGTGLSDPT PTLQKKQPAP PKLPVPPEEE LEERFSVVLS
YMNLPPDKLN LLSQYDNEKK WELICDQERF QVKNPPSTYL TKIKSFYQDQ GGVTRRFKRR
VQESTQVLRE LEISLRTNHI GWAQEFLNEE NQGLDVLVDY LSYAQCDASF DLEGAENGGT
LSERGKPAER SMEDLNKSAG SSPTHGMTRA ARALTVRITS LAQSRKTQKI SRLASQRDDV
HVCIMCLRAI MNYQSGFNQV MTHPRCVNEI TLSLNNKNPR TKALVLELLA AVCLVRGGHD
IILAAFDNLK EVSGEKNRFE KLMEYFSNDD SNIDFMVACM QFINIVVHSV ENMNFRVHLQ
YEFTHHGLDQ YLESLKLTES EKLQVQIQAY LDNVFDVGAL LEDAENRGGV LEHVDELQEH
NSQLSARLEE IESQSAERMA ELEKQLLQAT KETELLKESL RDSCSQVSSL QQREREREMS
QERERDRERL SQPSSELELK VQELQDRGLI RLGRTPSGAL DLQVVPVTII EYAPAPASEC
LLSSTGPTAP GPEVPDATPS SAISAVPPPP PPPPPPPGPG GRAPPPPPPS PCGSGGPPPP
PPPPPPGGGP PPPPPPPGGG PPPPPGGPPS GDSQAGGKSR KPIQTKFRMP LLNWQALKPN
QVTGTVFHEL DDEQVLGELN MDAFEEQFKT KAQGPPAALS TLKVKVAQKA PSKVNLIEGN
KAKNLAITLR KGGRSPTDIC TAIETYDQQA LGLDFLELLE RFVPSDYELK LLQNYEKEGR
PLDDLAEEDR FMMRFGKIPR LAQRISTLTF MGNFPESVKR LQPQLNSIIT ASMSIKSSAK
LKKMLEIILA FGNYMNSSKR GAAYGFRLQS LDLLLDTKST DRSQTLLHFI SSIVQEKYPE
LNNFHTELHF VDKAGLVSLD SILQDIRSLE RGMEVTKKEF LVQEDNTVLK DFVKTNSELL
DSLLKDSKTA QEAYGSVVEY FGENPKTTQP SMFFPLFVRF MKAYKQAEKD NEQRMRLEAK
SSENQAESPS PRKKEAAGHK SPMMPKMDLI AELKKRQVKP QVKDGALEDI ITDLRNSPFR
ATDGRRPAQR QDT
//
