ID A0A1S3S5P7_SALSA Unreviewed; 194 AA.
AC A0A1S3S5P7;
DT 12-APR-2017, integrated into UniProtKB/TrEMBL.
DT 12-APR-2017, sequence version 1.
DT 27-MAR-2024, entry version 24.
DE SubName: Full=Apoptosis regulator BAX-like {ECO:0000313|RefSeq:XP_014059662.1};
GN Name=LOC106607327 {ECO:0000313|RefSeq:XP_014059662.1};
OS Salmo salar (Atlantic salmon).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Protacanthopterygii; Salmoniformes;
OC Salmonidae; Salmoninae; Salmo.
OX NCBI_TaxID=8030 {ECO:0000313|Proteomes:UP000087266, ECO:0000313|RefSeq:XP_014059662.1};
RN [1] {ECO:0000313|RefSeq:XP_014059662.1}
RP IDENTIFICATION.
RC TISSUE=Muscle {ECO:0000313|RefSeq:XP_014059662.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the Bcl-2 family.
CC {ECO:0000256|ARBA:ARBA00009458}.
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DR RefSeq; XP_014059662.1; XM_014204187.1.
DR AlphaFoldDB; A0A1S3S5P7; -.
DR GeneID; 106607327; -.
DR KEGG; sasa:106607327; -.
DR OrthoDB; 5385020at2759; -.
DR Proteomes; UP000087266; Chromosome ssa06.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.
DR GO; GO:0042981; P:regulation of apoptotic process; IEA:InterPro.
DR CDD; cd06845; Bcl-2_like; 1.
DR Gene3D; 1.10.437.10; Blc2-like; 1.
DR InterPro; IPR036834; Bcl-2-like_sf.
DR InterPro; IPR046371; Bcl-2_BH1-3.
DR InterPro; IPR026298; Bcl-2_fam.
DR InterPro; IPR002475; Bcl2-like.
DR PANTHER; PTHR11256; BCL-2 RELATED; 1.
DR PANTHER; PTHR11256:SF65; BCL2 ASSOCIATED X, APOPTOSIS REGULATOR A-RELATED; 1.
DR Pfam; PF00452; Bcl-2; 1.
DR PRINTS; PR01862; BCL2FAMILY.
DR SMART; SM00337; BCL; 1.
DR SUPFAM; SSF56854; Bcl-2 inhibitors of programmed cell death; 1.
DR PROSITE; PS50062; BCL2_FAMILY; 1.
PE 3: Inferred from homology;
KW Apoptosis {ECO:0000256|ARBA:ARBA00022703};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000087266};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 173..191
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 67..162
FT /note="Bcl-2 Bcl-2 homology region 1-3"
FT /evidence="ECO:0000259|SMART:SM00337"
SQ SEQUENCE 194 AA; 21655 MW; 7307E60D746DB9F0 CRC64;
MAAPSGGGDS GNGTDQVLEL GEKLLTDFIY ERVRHHADSS TQLSVSRTQL GGSELCDPNH
KKLALCLQQI GDELDGNTQL QSMLNDTALQ PSHEVFMRVA REIFSDGKFN WGRVVALFYF
ACRLVIKALL TKVPDIIRTI ISWATDYLRD HVINWIRDQG GWEGIRSYFG TPTWQTVGVF
LAGVLTTVLV IRKM
//
