ID A0A1S3S9T3_SALSA Unreviewed; 8908 AA.
AC A0A1S3S9T3;
DT 12-APR-2017, integrated into UniProtKB/TrEMBL.
DT 12-APR-2017, sequence version 1.
DT 27-MAR-2024, entry version 29.
DE SubName: Full=Nesprin-1 isoform X4 {ECO:0000313|RefSeq:XP_014061104.1};
GN Name=syne1 {ECO:0000313|RefSeq:XP_014061104.1};
OS Salmo salar (Atlantic salmon).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Protacanthopterygii; Salmoniformes;
OC Salmonidae; Salmoninae; Salmo.
OX NCBI_TaxID=8030 {ECO:0000313|Proteomes:UP000087266, ECO:0000313|RefSeq:XP_014061104.1};
RN [1] {ECO:0000313|RefSeq:XP_014061104.1}
RP IDENTIFICATION.
RC TISSUE=Muscle {ECO:0000313|RefSeq:XP_014061104.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Nucleus outer membrane
CC {ECO:0000256|ARBA:ARBA00004605}; Single-pass type IV membrane protein
CC {ECO:0000256|ARBA:ARBA00004605}; Cytoplasmic side
CC {ECO:0000256|ARBA:ARBA00004605}.
CC -!- SIMILARITY: Belongs to the nesprin family.
CC {ECO:0000256|ARBA:ARBA00008619}.
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DR RefSeq; XP_014061104.1; XM_014205629.1.
DR OrthoDB; 5478539at2759; -.
DR Proteomes; UP000087266; Chromosome ssa06.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-UniRule.
DR GO; GO:0005635; C:nuclear envelope; IEA:UniProt.
DR GO; GO:0003779; F:actin binding; IEA:UniProtKB-KW.
DR GO; GO:0051641; P:cellular localization; IEA:UniProt.
DR CDD; cd21241; CH_SYNE1_rpt1; 1.
DR CDD; cd21243; CH_SYNE1_rpt2; 1.
DR CDD; cd00176; SPEC; 9.
DR Gene3D; 1.20.58.60; -; 31.
DR Gene3D; 1.10.418.10; Calponin-like domain; 2.
DR InterPro; IPR001589; Actinin_actin-bd_CS.
DR InterPro; IPR039906; Anc-1/SYNE1/2-like.
DR InterPro; IPR001715; CH_dom.
DR InterPro; IPR036872; CH_dom_sf.
DR InterPro; IPR047290; CH_SYNE1_rpt1.
DR InterPro; IPR047291; CH_SYNE1_rpt2.
DR InterPro; IPR012315; KASH.
DR InterPro; IPR018159; Spectrin/alpha-actinin.
DR InterPro; IPR002017; Spectrin_repeat.
DR PANTHER; PTHR21524:SF5; KLARSICHT PROTEIN; 1.
DR PANTHER; PTHR21524; SPECTRIN REPEAT CONTAINING NUCLEAR ENVELOPE PROTEIN 2; 1.
DR Pfam; PF00307; CH; 2.
DR Pfam; PF10541; KASH; 1.
DR Pfam; PF00435; Spectrin; 10.
DR SMART; SM00033; CH; 2.
DR SMART; SM01249; KASH; 1.
DR SMART; SM00150; SPEC; 40.
DR SUPFAM; SSF47576; Calponin-homology domain, CH-domain; 1.
DR SUPFAM; SSF46966; Spectrin repeat; 41.
DR PROSITE; PS00019; ACTININ_1; 1.
DR PROSITE; PS00020; ACTININ_2; 1.
DR PROSITE; PS50021; CH; 2.
DR PROSITE; PS51049; KASH; 1.
PE 3: Inferred from homology;
KW Actin-binding {ECO:0000256|ARBA:ARBA00023203};
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054, ECO:0000256|SAM:Coils};
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|PROSITE-
KW ProRule:PRU00385}; Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000087266};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|PROSITE-
KW ProRule:PRU00385}; Transmembrane helix {ECO:0000256|ARBA:ARBA00022989}.
FT TOPO_DOM 1..8857
FT /note="Cytoplasmic"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00385"
FT TOPO_DOM 8879..8908
FT /note="Perinuclear space"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00385"
FT DOMAIN 53..167
FT /note="Calponin-homology (CH)"
FT /evidence="ECO:0000259|PROSITE:PS50021"
FT DOMAIN 208..313
FT /note="Calponin-homology (CH)"
FT /evidence="ECO:0000259|PROSITE:PS50021"
FT DOMAIN 8849..8908
FT /note="KASH"
FT /evidence="ECO:0000259|PROSITE:PS51049"
FT REGION 1..34
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 185..207
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 311..337
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2586..2605
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 5932..5965
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 8294..8337
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 8761..8846
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 1829..1859
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 2284..2311
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 2353..2409
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 2812..2849
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 2988..3036
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 4179..4206
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 4830..4857
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 5698..5725
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 5804..5879
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 6112..6139
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 6216..6243
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 7117..7151
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 7216..7253
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 8..22
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 323..337
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 5935..5965
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 8297..8320
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 8765..8794
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 8814..8846
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 8908 AA; 1013312 MW; 2E26711F3A54BC2B CRC64;
MSSPHPHEGR GGSRRSLDHK MAQRSGGDGT PNKKTSLNLV TGFFHYLRDE QEAVQKRTFT
KWINSHLAKR VPSLVVTDLF EDIKDGVMLL ALLEVLSGQK LPCEQGRKLR RIHWVSNIGT
ALNFLEGRKS AYRGSPIKLV NINSTDIVDG RPSIVLGLIW TIILYFQIEE LTSNLPALQA
LSSSTSSVDS SDTTSPPVKR RPLPPLQGGA RKALLRWVQQ TATKHLGIDV KDFGPSWRTG
VAFFAVILSL RPHLVDMERV RRRANRENLQ EAFSLAETEL GIPQLLDPED VDVEKPDEKS
IMTYVAQFLK HHPNPGHQQN SDSDSQPEEE HGLAPRDIEE MLEREQRKGL RELKTWLDQL
ELDTARTQET KGNLSQQYQS FKSIRVQLEM NRKQVEAAVL STQKDGMLTV DQALVKQAWD
RVSNRLLGWH LQLDRALPAP LGVVGEWLHQ AEGALRQEVT IQQTSDATAN TVHMTLEQHK
DMLKGLEGHQ QVFQRIHKDR SVNGVPVPPE QLQDMAERMN FVSTSSNIHL AKMEFWENKH
HMQAFLMLAE SKLKSWIIKY GRRESVELML QNYVSFVEGQ QFFEQYETLF QSLKQSSELY
VKADGTVDEG EAGVRRFMRE VLTQWRSLSV EVRSVRSMLD EVLSNWDRYS CTVASLQAWL
EDAEGALSQP ENIKREFFRN LSQWMDQHSV MNDAGNFLIE TCDETVSRDL KQQLLLLNGR
WRDLFVKVKQ YAREDELDKW RRDHMMAISA LRELLDGAEE KLNAPVQVSF LNIRSFLQDV
ENTKKKVVAM ETQYKLAARS AQLLSKDAPQ EEGAKAMATM TTVKGQLSKV RERCPSLVRE
CHGLLPLLEE MEKHITGFYQ ALERASRITA AGRDPKPQAQ VQGQHKHKWQ DLLSQQQSCK
MCLSVIERNL HSLQRAISSS KALRNFDQTL LQKRVAEIQT SAQGLLKEVG EWRRQEEANS
TMRRRFEESR QELERVLKVA TTCLREGGHA EELLKKQSEF FGQLDQRVLS VFLKACDDLT
DILPEEEQQA LQDTVRMLHK QWKDIQMEAP FHLQRLKVEA ERGRAGAVLQ ECRAELAREN
QALTTTGSET VIREHRAFFR EKAPLSVCEK SIGNMEELCQ TLPDNDPARQ TLDSTRRALA
DVKGQIEATH LKLQHHSQWR EWNDRFSELS KWLLSQRSQV RLLRERARDR SHQEQVDTTV
QQLQRAAEGQ EESLSWLNSR LAVLTEVSPE VEAIRQRAAL AKLSSDLTAL LSSLLEWGQE
RSVRVHSEEL REDVRCALEE VLRARREAQE QTSRILEAEN PEEARQLLLI HQQHLKRLQT
DRKKAELLVA HCRQLQKGEG LSSSLRELED TFREVDRKVG AQEHNLQATL GAWQEFDAER
EAVWQFVSST SPVLQRELIF SSLDSLRTEL GCTKALHKKS GEYVVQTDCL SRKAAEIQLG
PKNQTLLQQQ AQQATQQVAQ LEASLKKNVD LLEMVCVWWE RFIRESEAFS SWISEREQEL
DTVDSNSSSD PLDKHISTVE SVGARLEERA AILSHLEAES EALSGFVTPG EAGRIRARLA
QMERYWEELK ESVEQLGGQL NQSATCRQRF IDNLEQVKTT MVGLKEKLDI TITCCTSASE
TYRVLQDHMD VVQALEQLNP RLVALCLGKK RLGKGDLLEG EVANLQKNQG EYIEQAAEKQ
ATLEKLLALW QKYEKESSSL RSWLDRCESV CCPDTQLLST DKAKLMNELQ TVQEMQSDLQ
SHEAFLQGVV SLGPCLYPTA PEGRVRELTD DITQLEERCT SVKNSITQRL QQLQTHLSQV
ELFDEALLTL TQWSENFLSV LRTTSQVNIA DLQAAVTQVK EHEESLQEQT ALRETLQQRE
SSLLSFSSPE AQQQLQGQRE DCLQTLSEAQ HLLLLRGESL AELGDFLQSH GAAAGAVRGL
REAVEGRGSW DRSKAEVLHH GLGEVAGDVA RLEAQAVGLD GRLSKAHLHL SGAEWKGSRE
GGLGQGPGQG RTSCRGQAVA LMVALEGVQR GLGWRQSQAE ALGALWTSFR ERREEVMRSL
RELEERARQE GARESSVQAF QNSLRFFVQL EDELQSLQHS QQWLRERGSQ LAQRDSELAG
EALREVGLVE TAWENVRKII TNGQEQCGLL VELLRHFHSL RSTLSSTVEN ALTVTHNQPD
HTHNPEDAKR LLSRHEAVIA ELRGRQEDMD LFISSGEDLQ RELVNVPHCG SNSIQRGMDT
LRDQWLQVSE RIQTNAERLG HCVSLWDDLK TMERDIDQWA AASIADLTEG VANLSDKQAT
ETHLATFQAE VERREQRLDA LQERVTKLKD LAKLQETPIQ LQVMECDLRK KISHAQEVFD
QARHSLTYFS FQKQRLEDLM SQMAERLETV ESSLSDLTEP SGPEDMIRVK DLQSALQQQR
GDIDMAREML SSLCRSHPSQ ELTHMSSDLT LLAKRTDAAA QLSYRTRGTL QDALQQRFNK
VVQEFNSWLS ERKAELKECS DQSGDVTSLG TKVERLKVAQ ERVEEGEQHL GQVCGEAERL
LLHLPKAGSG QVQERLSSCQ RDWDGYKEGC RQTQQDLEEG IALLTEFEGR VEGLRDWLEQ
MERSLKREHP LGGEEQPGVP DSTDELERVE EIHRKLLTKR SSLDRLSQEA QSMREAGRGC
GGEVKATAQL QTHHQALLQG TRERLRGCLE SQAFGETLHG VWLWLEDIQE RLGSLGSTMG
NKKELEERLE QVQDILLLKG EGEVKLNMAV GKGELAIRSN SAEAGQEVIR SQLQEVEDVW
ATLLVTAMSC HSRLEWTVAQ WGCYLDSEAQ LQCWLEAVEG DICGPLIPQP GLREKASQLE
RLQTLLADLQ EHQGSLSSLE ERAAELYKKT GDAAFSQEAR AELQGQFDDL IALVEERVRL
SEGVVREHQQ YLETVRELTD WLMSAGEELQ RWSDTLGDSV SLQRRLSEVR ERVECRLLEG
RDRLSRVRRS SGATAEHTAA GGCEAMDRQL GALAQALEQW EGAALRARDG LERALTTATE
QEQEYERLTA RMEEELRELD GRLKGWSQEL SRAEGRSSGE EAVEGWQQAK EILEGLLSAE
PMADRLKAQL NDLVRYSRDL GPHSDRVTAL IKQHNSLSLR ASRECQNKER LLEQRFRAAL
RDFQQWLVNA KISTAKCFDI PQSVTEASTG LLRIQEFLND REHGQARLSA VGTSGELLMA
VVPKDREEGV KAKVANARDD WKSLMTNLQM RETALKNLQS QMRDFEVSTE PLQDWLNSTE
VIVQESSARL HDLPAKRQEL SKLQCVLEEL SCREAELGKL RERAHRLWEG QAAGKGFVHR
VSQLSAQYLA LSNLTKDKAS RIERIVGEHR LFSQGLTELQ NWVSEAERIL NTCLSPTADK
TVLEDRMIQL EALLAARQER EIQLKMLLTR GEAVQRNTSA EGVPVVRKQI QDLKDSWDSL
LSASIQCKSQ LEGALSQWTS YQEDVGQFIM WMERVEATLG CSDRQYSEMR DKTANLGKTK
LLYEEVLSHS SPLETIATKG SNMAEQYTTH QEVHSLQERY TAITDKAKAA VYKAKDLVLA
HQEYQRGLHM FEDWLEQEQG TLGSLSHPEG DVDTLENTLQ QIQLLQERCS QGQSLLSSLL
SSRDGVIPWG APQIEDRALD TAQREWGAYQ ARLGETRATL GSTLGRLRQM GQRFQSLALW
LEDMEGKANI RGHRRSDSAS KDAQLKQLQL WQESVLARQS EVDGLSALAQ QVLEETHISS
RVSTRATQLT ARYHALILNI QETIKQLKEE LRSIEEAEKL CVSFSDWLRS AQKNFRTVTA
STEALDRVAM ERKMKQVETL QAELQQGHGL LKALRERAER AAGFLEEAGA EGLGGEVEAR
LAQLEELAGG LRQEYSTLER AVCLAKEFQD RYKAQARWVV ETRAMLSAPL EPKAELYQKR
AQLAKYKALL QTVQSHDSAV RLVVEKGESL LLSVQYPSIR DNMNRLQTDY TELCNAATAH
VQRLEGQVKE QEVYHVELQE VERWLLQMSS RMVTPDPAAG GGLEAATQQL ASHKAIMEEI
AGFEDRLAGL KERGEDLVEG CSERVQSRLR QQVQAQQQGT RDSYSAICST AQRVYQSLDR
ELQRHVSLQD ALQQCQTWLV SVSEEPEPTA HLPLSLEEAL QQVKHERTLQ EQASTYLQLV
CSTCDLSEQR VRETAQDIQQ VKLQIEERML VCEEVAESWR DVQEQRADLE AQLRETEQQL
QNLSRRPAEL EPKITQNQLD QAQEFLQQLR VRQVDVTQLS EAVAGLTEGQ SSPALEEMGG
LRRAWEELGQ RAEELEGQRG EDMQRSGEYH DCVAAVEELF HQVSREWDYL ARADTESTSE
HLEALRKLCC DLEDQRGTLE ELRDQRQAVL PRLSLLDKEL VKQQVGHLEK RWSQLDSLIQ
GKIQDSSQTL EDLGRVEAQL REAREWMEEQ RPALTSALKT SPPPDLAQSF LFDHLSVCVE
LEARGQLLGQ AVSEAQRVAS RLGLSERRRL QELVLQAEGE VEALGARVSQ RRKYLSKAFT
ERTQFLQAVG RALSWVQQQE RKALMDDHVA LLPDDLTKQV VTCRGVQSGL RAYQGELASL
WAQGRDLERD ATDQERGETV TRLEELQRVF ETAFQRTTHR LQDLDRALTS RKYFKVDLDR
TCHWLRRADG ITFPEIDFTC NADDDSELQG RLAKLQNVLE QASEYENLLL IVQRVGQEIL
PSLNEVDHCY LDEKLNALPQ QYNSILALAK EKRDRIQQAI LERKDYDCFF NVTCSALEEL
QEQLDGLAKR TVSIQEQEVV HLRDDHRDLS ESLAQLSPAV RELRRKTEGF LSRGQRCHAE
ETEQLVNLHD NLKRTIDQRL KHLDDSLKTL AEYNATSAKL NSQLKSVKEQ VTRMKSDSDT
KLGGTERLAS LYTLLEDLER MGSHLERLTQ HTEDMGLNCD PAAIQASREV VTSHQKELQS
LRSEVKGCVT ECENCLKKDK EFEKEIGRTS DWLKILRKKL GEPLTLPEVK VERVEEEVRR
LKVVEEEVQS RLRVADAMGS REKQRYSSRN EACPAYVEAN LEELAKLRAD VQQALRTKQL
SLDQTLSLVQ RHQSTQQSAR KWLDEAGAFL QRSTLGIELE CQTESLRELE EISAQEPAFM
AKLEELETLG AQLDDLVGLG VTKEMKESER KKEGVEVMRQ KGSEVKEQLK GYREDLQSCA
AQWSSFQTER EELIGQMNET GSMMTAFPSA KAANSQEAED KLQSYKSLVI LIDGCEPTLT
GLKEKATDLA LVGSESSKAA IGHSVSSLCQ RWTRLRSVAR AQEKALEDTA RDWRSFREKM
EKVRSVSVDL HARVPDSTVE KAATRAALQN LLEYHDTFSL EVEREQSALA LLGQHTLSLI
GEDQEEEDME MEKTDKTREE TPWLKEIRSM QEIYESLVLQ VRGSRAQVQQ ELREREEVER
ELGLVKGWIQ DTRGLLLSPS SDLDSLLHEL ETAHGEVISR RQSVERMVEL QQNKYQDLQT
ALPSELSMQL AEVTLALGSA EDQVQSRERE VQQTRDVKED FSSRLQDIEG KLKTISLKIS
EKAIDLEQAK EETKCLCEEC EGCGRSLAEL VVAVQEFGDQ NPLLCKQLGD ALTRLAEVQR
LTTQQAQERA NQLHKAEQQL EEYKGMRQFL LGWAEKAETL VTGNIIWSSA SQLQEQIRAH
QAVLRECHGL NGDLEAMGER EGQLGEVLQT EGWSQQVKQL SRCTEELQQS AKTRLQSLQD
AAKDMVRLEA EVKTLHDSLD QAQLTLTSPD LARLSLREQL THRQRLLVEM EAFKQQVQAV
QLCQSALRLP EEVVANLSIC RTAQSLQQEA SQLQHTTIQQ CNILQEAVVQ YEQYEQEVRN
LQRLIEEAHR IIQDRPVSTS NIHELQAQIH HHEELALKIR GYQEQIASLN SKCKMLTVKA
KHATMLLTVS EVEGLSDGMD ELSDEELPTK QPLAHPSVVM MTAGRCHTLL SPVTEESGEE
GTNSEVSSPA CRSPSPGANA DTPLNQARAP LSRAPLQELY DPSLESNANL DDLQRSWETL
KNVISEKQKT LYEALERQQH YQESLQSIST KMESIEGALN EGLESRKSPE SQMAAHQALM
DEILMLQDEI GDLQTCFSEE LCDGLDSDSD PGDQLALHST LTVLGERMAT IRMKASGKRQ
LLEERLSEQL EEQRQEQALQ RYHSEAEELD HWLLSTKATL SSALQPHPED MDMEEQLIDC
QNMLFEIEQK VASLSELSVH SESLLLEGRA GTRGEAEQLT FKLHSLKDSL VELQRMLQDK
QVDIQGSLQE QEDSEPDSIL SQSPNIQDWL SQARSTRTQQ HHDNLLRQRE LEEQLAEQRR
LLKSVASVGE EILSQQTAPN GDSEGKPGVL LEAETLTPQD QMRQRWENLS KDQSTKLQLS
LNSLEQEQLS PVLHRSCVSS PGVVFRREAL GQDPYFPRAL FEGCSQTLER LAQEPGGVAD
NKQDVPRGVS VLEELYAAVS AASSWLDSAE NNVLSGPVLL SEDTETQLSN LEGLSKEVRE
VTGEMSKCRE LLGGGGGAAA GGRRLYGEEE QALMEDTLDG LQERLGLLDQ TLEQHCDCMR
DRLQEHTGFQ TELRLLFTAL SESKHQLLQR MAGAIDRPAP KQMETLSEVE DGLREFEQRV
AELRSRAEGR QPDQISNQEL LKLQDAYEEL VLMVGSRRSS LNHSLSLKAQ YESALHDLTD
LVDTAQDKMA ADQKMTVGSV IEVQILLDKH KEFFQGLECH MILTQTFYSK VSGLVVQRES
QVLEETLALA NNVLKQAHRR GVELEGILES WSMLVEDYQA LYRQLEAVEC SIPTVGLVEE
TEERLSDRIT LYQRLKTSLT EHQPQLYQVM EEGKRLLLSV CCSDLENQLT QLGEHWLCST
TKVNKELHRF DSTLKHWSRY QSESAELSQW LRSALDRLEF WTTQSVTVPQ ELETVRDHLY
AFLEFSKEVD AKSSLRSSVL STGNQLLRLK RVDTAGLRSA LAQVDTQWAE LFTRIPVVQE
KLHQLQMEKL ASRHAITELM SWMSLMENVI AEDQQRIMGA VGSEVVQDYL QKYKGFSIDL
TCKQLTVDFV NQSVLQISSQ DVEGKRSDKT DFAERLGAMN RRWQILQGLI IEKIQLLEGL
LEGWMEHENG VQALKTWLTL QEDKLKKRHR IDDVASVQNA LKDCQELEEL VKEKEKDLEK
AEERGSRLIQ EKRGQACSVV METLKGLNQS WTNLDNMIGQ MKVSLRSVLE QWTLYRRAAE
EINGYLMEGR YSVSRLHLLT GSLEAVQQQV ESLENLQEEL DKQESSLRKF GSVTHQLLTE
CHPSVAETLD GALRDVNIRW NGLLEQISEQ LRTSKALLGL WQRYTELYDQ CVSAVHRQEE
RADRLLKSAT DRDVTEEESN AWIRDCSELL GAQATVQQSL LQLQQLGQQL KTQVDASSMA
ALQSDCLSLT HRLATLEHAL HRQQEVLQCG AEDCERFKEQ LDSLTCQAEE AEEVLRESDP
VGTPDLTVIQ ERMEKLKSQM CKLSSHSPDL ERVNELAYRL PLNDSEIKRL QSLNRAWTSH
SAHLTERFSK LQAVLLQQQS FLQKCEDWMD FLSQTEQKLA AETSGNYHSL LEQQRDHELF
QAEMFSRQQI LYSIISDGHR LLDQGQVDDR DDFSLKLALL GNQWQGVVRR AQQRRGIIDS
LVRQWQRYRE MSEKLRRWIQ EVSRDPEVHQ QGEAVALQQA RTMLDQIQLR ERVLQRQQGG
YILAVEAGRS LLLSADARAE SALQTELMDM QECWRHANVR LDEQKRELLS LLKDWGRCEK
GIAASLEKLR AFKRKLSLPL PDNHEELHSE QVRCKELESN VDGWTDDLTS LFLLRDSLEG
VVSADDLTVL QDRLLLLQRQ WEEICHQLSL RRQQVSEKLN EWAVFNEKNK DLCEWLTQME
SKVSQNGDIS IQEMIEKLRK DYQEEIGVAQ ENKQQLQVMG ERLARASHES KAAEIQHKLS
KVSERWQHLL DLIAARVKKL RETLVAVQQL DKNMCSLRSW LAHIETELTR PLVYDTCDAQ
EIQRKLNQQQ DIQRDIEKHS TGVASVLNLC EVLLHDCDAC STETECDSIQ QATRGLDRRW
RNICAMSMER RLKIEETWRL WQKFLDDFSR FEEWLKTSER TAALPNSSGV LYTIAKEELK
KFEAFQRQVQ EFLTQLELIN KQYRRLAREN RTDSSCRLRE MVHDGNRRWD NLQKRVASIL
RRLKHFIGQR EEFETARDSI LVWLTEMDLQ LTNIEHFSEC DVQAKIKQLR AFQQEISLNT
GQIELVFRQG EALIEKSEPL DGAVLEEELE ELQRYWQEVF GRVDRYYKKL TRLPLADDEL
DCSDRDLDMD ESADLSDLQW GDSSLPCPSS RPTSGSVLPP QADRSGRDTP ASMDSIPLEW
DHDYDLSRGL ESAGGRGLGS DRGRGQEQEE EYLRSAAAVL SDVVIPESPE AYIKLTESTL
RSSSGEPGQL EAHLRQLDQA VDSGRYSVQQ GEAAACSGQA STSPELDSTY MGYMRLMGEC
RGSIDAVKRA GGQLTEEDDN MAGLTNPTST DSQSAGVIER WELIQAQSLR DKHRQKQNLQ
QCHQLISELQ TMRAWLCEAE AELGQLRVLD LSTDIHTIQQ RIRKLKELQK AMDGHKSQVL
SINLSSADFL QSEPDSEEAW ELRDGLKEMN SRWDWLGSSL EDWRAELQRA LMQCQEFHEL
SHGLLLWLEN IDRRRNEVVP IPPRLDRETL RAHHRTLTQI KRELLDSQQK ASSLQELSAQ
LLVHTQATSQ IQPQASEQAQ NQAQGSEHLE AQEKVHVIGN RLRLLLREVS TDLEGLERRL
ETMDTQQDSL PLSPVDKSDI SGSTSPVSDG TSTSRRRSPR GKSSHAHPGP PESGPHHSSQ
SGAGCASSRS DFPLVPSSSS SSSCPPRGQS FILRVLRAAL PLQLLLLLLI GLACLVPMTE
EDYSCHHANN FARSFHPMLR YTNGPPPI
//
