ID A0A1S3S9U8_SALSA Unreviewed; 524 AA.
AC A0A1S3S9U8;
DT 12-APR-2017, integrated into UniProtKB/TrEMBL.
DT 12-APR-2017, sequence version 1.
DT 27-MAR-2024, entry version 19.
DE SubName: Full=Transmembrane protein 181 isoform X1 {ECO:0000313|RefSeq:XP_014061116.1};
GN Name=tmem181 {ECO:0000313|RefSeq:XP_014061116.1};
OS Salmo salar (Atlantic salmon).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Protacanthopterygii; Salmoniformes;
OC Salmonidae; Salmoninae; Salmo.
OX NCBI_TaxID=8030 {ECO:0000313|Proteomes:UP000087266, ECO:0000313|RefSeq:XP_014061116.1};
RN [1] {ECO:0000313|RefSeq:XP_014061116.1}
RP IDENTIFICATION.
RC TISSUE=Muscle {ECO:0000313|RefSeq:XP_014061116.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR RefSeq; XP_014061116.1; XM_014205641.1.
DR AlphaFoldDB; A0A1S3S9U8; -.
DR STRING; 8030.ENSSSAP00000022002; -.
DR PaxDb; 8030-ENSSSAP00000022002; -.
DR GeneID; 106608014; -.
DR KEGG; sasa:106608014; -.
DR CTD; 57583; -.
DR OrthoDB; 5478455at2759; -.
DR Proteomes; UP000087266; Chromosome ssa06.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0015643; F:toxic substance binding; IEA:InterPro.
DR InterPro; IPR040416; TMEM181.
DR InterPro; IPR047843; WLS-like_TM.
DR PANTHER; PTHR31918; TRANSMEMBRANE PROTEIN 181; 1.
DR PANTHER; PTHR31918:SF1; TRANSMEMBRANE PROTEIN 181; 1.
DR Pfam; PF06664; MIG-14_Wnt-bd; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000087266};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 58..79
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 224..242
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 262..285
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 291..312
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 324..347
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 367..391
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 403..425
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 445..466
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 173..470
FT /note="Wntless-like transmembrane"
FT /evidence="ECO:0000259|Pfam:PF06664"
SQ SEQUENCE 524 AA; 61325 MW; 1DFAED6CD4236F60 CRC64;
MDTDYLAFEN PLYSELKYFC KKIQEVYNEL KEDLTPYRDD RFYRLAPMRL YTLSKRHFVL
VFVVFLICFG LTVFIGIAGP KILAETKYSG DELLDKNQSI KTGPFILQSP PLSTYNQQLW
LTCIMQVEHS TVVDFLQHFE INVELKGVMQ DASVMHIRSN VHQKSRMLHC GAKCDEIIVV
HLGYLNYTQY QINVSFKGLE NITYEVKVNF MWKMYNPSFS QVEIWFRFVF VVLTFMVTCM
FAHSLRKFSM RDWGIEQKWM SILLPLLLLY NDPFFPLSFL VNSWFPRTLD AFFQALFLCS
LLLFWLCVYH GIRVQGERKC LTFYLPKLVI VGLLWLSAVT LGIWQTVNEL QDPTYQYKVD
IANFQGMKIF FLVVVTLYIL YLIFLIVRAC SELKNMPYTD LRLKFLTALT FVVLIISMAI
LYLRFGAKAL QDNFVAELST HYQNSAEFLS FYGLLNFYLY TLAFVYSPSK DAIYDSQLKD
NPAFSMLNDS DDEVIYGSDY EEMPLQNGRA IKATAKYQNE SDSD
//
