ID A0A1S3SBW7_SALSA Unreviewed; 3161 AA.
AC A0A1S3SBW7;
DT 12-APR-2017, integrated into UniProtKB/TrEMBL.
DT 12-APR-2017, sequence version 1.
DT 27-MAR-2024, entry version 25.
DE SubName: Full=FRAS1-related extracellular matrix protein 2-like {ECO:0000313|RefSeq:XP_014061830.1};
GN Name=LOC106608422 {ECO:0000313|RefSeq:XP_014061830.1};
OS Salmo salar (Atlantic salmon).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Protacanthopterygii; Salmoniformes;
OC Salmonidae; Salmoninae; Salmo.
OX NCBI_TaxID=8030 {ECO:0000313|Proteomes:UP000087266, ECO:0000313|RefSeq:XP_014061830.1};
RN [1] {ECO:0000313|RefSeq:XP_014061830.1}
RP IDENTIFICATION.
RC TISSUE=Muscle {ECO:0000313|RefSeq:XP_014061830.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the FRAS1 family.
CC {ECO:0000256|ARBA:ARBA00005529}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR RefSeq; XP_014061830.1; XM_014206355.1.
DR STRING; 8030.ENSSSAP00000007128; -.
DR PaxDb; 8030-ENSSSAP00000007128; -.
DR KEGG; sasa:106608422; -.
DR OrthoDB; 4059163at2759; -.
DR Proteomes; UP000087266; Chromosome ssa07.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.
DR GO; GO:0007154; P:cell communication; IEA:InterPro.
DR Gene3D; 2.60.40.2030; -; 5.
DR InterPro; IPR038081; CalX-like_sf.
DR InterPro; IPR003644; Calx_beta.
DR InterPro; IPR039005; CSPG_rpt.
DR InterPro; IPR045658; FRAS1-rel_N.
DR PANTHER; PTHR45739; MATRIX PROTEIN, PUTATIVE-RELATED; 1.
DR PANTHER; PTHR45739:SF8; TNFR-CYS DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF16184; Cadherin_3; 11.
DR Pfam; PF03160; Calx-beta; 5.
DR Pfam; PF19309; Frem_N; 1.
DR SMART; SM00237; Calx_beta; 5.
DR SUPFAM; SSF141072; CalX-like; 5.
DR PROSITE; PS51854; CSPG; 10.
PE 3: Inferred from homology;
KW Cell adhesion {ECO:0000256|ARBA:ARBA00022889};
KW Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000087266};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Signal {ECO:0000256|ARBA:ARBA00022729};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 3017..3038
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT REPEAT 307..407
FT /note="CSPG"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU01201"
FT REPEAT 430..524
FT /note="CSPG"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU01201"
FT REPEAT 545..657
FT /note="CSPG"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU01201"
FT REPEAT 682..788
FT /note="CSPG"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU01201"
FT REPEAT 810..901
FT /note="CSPG"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU01201"
FT REPEAT 1046..1148
FT /note="CSPG"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU01201"
FT REPEAT 1169..1262
FT /note="CSPG"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU01201"
FT REPEAT 1283..1389
FT /note="CSPG"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU01201"
FT REPEAT 1411..1503
FT /note="CSPG"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU01201"
FT REPEAT 1523..1613
FT /note="CSPG"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU01201"
FT DOMAIN 1760..1861
FT /note="Calx-beta"
FT /evidence="ECO:0000259|SMART:SM00237"
FT DOMAIN 1874..1985
FT /note="Calx-beta"
FT /evidence="ECO:0000259|SMART:SM00237"
FT DOMAIN 2000..2106
FT /note="Calx-beta"
FT /evidence="ECO:0000259|SMART:SM00237"
FT DOMAIN 2119..2223
FT /note="Calx-beta"
FT /evidence="ECO:0000259|SMART:SM00237"
FT DOMAIN 2241..2345
FT /note="Calx-beta"
FT /evidence="ECO:0000259|SMART:SM00237"
FT REGION 1..27
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2920..2968
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 3050..3161
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2951..2968
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 3074..3089
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 3107..3161
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 3161 AA; 347468 MW; 04B1DBBC684CB94B CRC64;
MATTTAGEEL DAESSPGRQH RHQTTPTKQK RQPLSWIYLC ICLILDLCCL SVEGTNWHQY
NHRHRPQPGS VILGNRGLKV PRGSWVYLDP SCDLVIRVLP GDRCYITVFD YDRAVIPGTL
TPKKFLCSFE KGQVKYMHFG SKVITRDTVR LQVRYDTRTD TLVIPLTLEV EVTANGREVV
TTNTPLIVSE LDGISNAISG QSLGIPFRGS SFGTGGSASQ CKLSLLIGTG GFPRHGTLLN
YVTDAQPTDC DAFVNMDVRY KLTPTSDSPH VDYVPMLVEL LDKRGRATQQ EYFLITVRIR
ERVINSPPRP SFLSMMMMEV DQFVMTAITS DMLAAEDAES ASDDLIFDIL TTLTPDQGDI
ISTDDQNQPI TSFCQRDVED LKIAYRPPAE DFAHPSERIV HVELKVVDSD GVTSEQFSFM
IIVKPMNTLA PVVTSNTGQM LFKGQSRPLS SNHNLRISDE DNLSDVRITV LRGCKHGVLT
VLGSPLGSPR QRKFFTPAEL DSGVVVYEHD GSETFSDNIL FRMTDGRLDV DFLFPVTIVA
MDDEAPVIHV NTGLILSRKE TKMISSVVLS ATDVDSEVST VKFVLVAPFS TIGQVFLRQS
HPPVDLTGWT FNTTERVYEC VVTEWLQRDI TEGRVFYQHT GPRLTSTFTD QLVFHCQDDN
VPPNQSGDNM FLVRIHPVDD LAPEPFPGST LVLTVKEYQL TPIQKTSLRF TDLDSEDRDL
RYIIVIPPTN TDQNNPTPLG HIVLTDNPNV VVTEFTQAQV NHLKVAYKPP DLELGTTPRV
VRFTFIVKDT IGHSVNGVFT INLQPVDNKP PVTNTGVNLN INVKDTYVFT KDVLDATDQD
TSADNITFIV TQVPKFGVLR CAGVDLSVWN NFTLAYIHRG VVVYIHRGNG PGSDVVKVDV
SDGYHKVPMT IRINIVTPAV VATPPTAPPT PGELHIIVEV NENGQIQITG DEVQVSGRMR
VDDLTFLIEQ PRFGVIRVQG VPSDRLTLRD IIDGRVTYVH TSGEVGPGKH NDTFTLTVIG
PWISRGNRVI QKVKVQVSIL PVDSVPPILL VGDLLKVTEG QKKVVTVENI RVEDSDTAVD
VVLCTILVQP TFGYLEITSP SPGSEKSRAG IAVTAFHYRD VRLGNVVYVQ SIHKGTEPVE
DRTTLQCSDG INQSDISILT FVIFPDNDEE PQVFTRDFVV MEGMSLTVDV PILNVVDLDV
PGDVLEFEVV VPPKHGKIVQ HLATGTVIVV TFSLDQIRTG STIVYKHDGS ETRHDNFSVK
VTDGKHVVEK KVIVTVIPVD DETPRLAINN GLEVEFSGWK VLTNKILKAT DLDSEDTTLM
FIVRQGPGQG CLQRLVSPAS YQGLVASQKA LVNITVGMNF TQGDLDSGLI HYLHTGLGGV
RDLIKFDVTD AANPLIDRYF YVTVGGVDAV FPVVVVNRGV SLKEGGRALL TTDLLSTSDL
NSPDERLTFT LTRDPARGRL EVTDRPGVAV TTFTQLQLAG SKVFYVHTAE DEARMDNFQF
QITDGRNVVY RTFRVSITDV DNKKPVLTIH RLVLVAGETK LVTPFELSVK DRDTPAGQLI
FTVTQQPLHG RLLYNGTRVA TTFTKLDLME NLVCYKHDGT STNRRDSFLF TVTDGTHDEF
YVYPETGHVT VRPQKLEIQV NVVDRTGPRV LVDKPVSTLK VLHTGQLGLL FTSKVLRVEN
QEDRRGQGTK ERVQPRRDIT FWVSEAPRWG VIVNTALGNG SVTSFTQDDI DQRRICYILP
ATVNSTSDVF HFTVQYNGGN RVTQQPFRVQ WAWVSMETRL YTVQESSQFL EVALRRRGHL
GETSFVTVSL HDITTERGQD YHASPPKQVQ FNPGQTRAVW RLRIHDDQVY EGSESFRLVL
SEPVMALIGQ SSSVTVEILD PEDESVVFIP QLEFRVEEDV GEVLIPVRRT GDLSNELTVL
CYTQEGSARG TVPGTLLSYS DYISRPEDRR SALRFDRGDA ERPCRVLIID DSLHEGAETF
AVTLGDAMGG LVRAEHNSTR VVILPHAPDE PVVYLGRSEY SVDESCGYLE VSVLRSGTDL
SHNASVTLRS RSTQPVSALA GLDYVGIGQS VDFPPGVTVV TVKVTILDDL GGPVMEGEES
FQLVLSMPSN ASLGRPSLAT ININDTMSDL PKVQFREVEL RVDEADGRAV AAVTRDGDLS
LTSVVRCYTR QGTAQVTTDY DERPDTDDSV VTFRPGEREQ QCIVTLVDDL EFEEEEEFRL
VLGFPRSQLD LGLLLGQQME LVVRITDSSD KSVIRFSEPR YTVSEPVAHG EVTVLRVAVQ
RHGDVSRVSV VRVHTKDGSA HSGQDYTPLS QELVFSEGQT ERLVEVEVLY DEEGEMRETF
TLQLTPDQHM VADTQVTKAT VFIEEKEGGD VGSITFPAVP LVVSLLVYDD PSLAPTPTSP
HPPTGYPLVC VTACDPRYPD YSRTLSLCVS EGINNTLTEY RWLLGSPGTP DGVASPPREL
DAGTFLTSTS SMLLDAVYLQ AGARVQCSAR AVSTAGRGGL GLTSPQVEVS MEKGLCPPHT
PGAIGAEPFS AKIRYTGPDD PEHPNLIRLT VTMSHVDGML PFISTRPLSN LALTLNHDPS
RLGNHRCSNL QGGPGDASAT RLGLTSTGAA VAGVVGGSRL RNSIAQDGAL SLGFYNSLDL
EACVWSFSGY YSISDLLSDC GGTVRTDGQV LNAVQSYVTL RVPLFVSYVF HSPSAPGGWL
TFDLRSDFRM TFTYDTSILW RDGIGSPPDA PLQGNRQTRL DVRFQQVSGP VPVEFSLNTV
LVLLSKRELW LSDGSMGFGQ DDDIAFSKDA VIYGRVMVDP VQSLGNSFQC HIQQVFLCTG
ADGYVPKYRP SNGEYGCLAD ASSLLYRLKI LDQAEPQSQE VEFGGIRFEA RLAGDTPGAF
PLVSQPDADG FSLSSAPLFQ VAAGHEWYVH VVYTVRSRDH GNRNYNNRNH TVGKRSLFPQ
HHVISSGGRQ KRAAPEKERG EDQDRGTNLR HVHLQRAPSL GQSWAEGPLM DWELQERGES
PVGSPERETL DGAKGSMTLA VVVLVAGCLG GVVVYAVFVR RETIRSLDCL SSSSFSSSSR
RALPRGGEEG PPSTLPGPVH PPGPRPPSRA TSTLPGAVHA PGPRPRSRAP STLPGPVHPP
GPRPRSRAPS TLPGPVHPPG PRPPSRAPPP QEPPSPQESF C
//
