ID A0A1S3SF89_SALSA Unreviewed; 355 AA.
AC A0A1S3SF89;
DT 12-APR-2017, integrated into UniProtKB/TrEMBL.
DT 12-APR-2017, sequence version 1.
DT 27-MAR-2024, entry version 29.
DE SubName: Full=Cysteine-rich with EGF-like domain protein 2 isoform X3 {ECO:0000313|RefSeq:XP_014063000.1};
GN Name=LOC106609106 {ECO:0000313|RefSeq:XP_014063000.1};
OS Salmo salar (Atlantic salmon).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Protacanthopterygii; Salmoniformes;
OC Salmonidae; Salmoninae; Salmo.
OX NCBI_TaxID=8030 {ECO:0000313|Proteomes:UP000087266, ECO:0000313|RefSeq:XP_014063000.1};
RN [1] {ECO:0000313|RefSeq:XP_014063000.1}
RP IDENTIFICATION.
RC TISSUE=Muscle {ECO:0000313|RefSeq:XP_014063000.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the CRELD family.
CC {ECO:0000256|ARBA:ARBA00005897}.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00076}.
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DR RefSeq; XP_014063000.1; XM_014207525.1.
DR AlphaFoldDB; A0A1S3SF89; -.
DR STRING; 8030.ENSSSAP00000010186; -.
DR PaxDb; 8030-ENSSSAP00000010186; -.
DR GeneID; 106609106; -.
DR OrthoDB; 337149at2759; -.
DR Proteomes; UP000087266; Chromosome ssa07.
DR Bgee; ENSSSAG00000005064; Expressed in ovary and 16 other cell types or tissues.
DR GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR CDD; cd00064; FU; 1.
DR Gene3D; 2.10.25.10; Laminin; 1.
DR InterPro; IPR021852; DUF3456.
DR InterPro; IPR001881; EGF-like_Ca-bd_dom.
DR InterPro; IPR000742; EGF-like_dom.
DR InterPro; IPR018097; EGF_Ca-bd_CS.
DR InterPro; IPR006212; Furin_repeat.
DR InterPro; IPR009030; Growth_fac_rcpt_cys_sf.
DR InterPro; IPR002049; LE_dom.
DR PANTHER; PTHR24038:SF13; PROTEIN DISULFIDE-ISOMERASE; 1.
DR PANTHER; PTHR24038; STABILIN; 1.
DR Pfam; PF11938; DUF3456; 2.
DR Pfam; PF07645; EGF_CA; 2.
DR SMART; SM00181; EGF; 3.
DR SMART; SM00179; EGF_CA; 2.
DR SMART; SM00261; FU; 2.
DR SUPFAM; SSF57184; Growth factor receptor domain; 1.
DR PROSITE; PS00022; EGF_1; 1.
DR PROSITE; PS50026; EGF_3; 1.
DR PROSITE; PS01187; EGF_CA; 2.
DR PROSITE; PS01248; EGF_LAM_1; 1.
PE 3: Inferred from homology;
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157, ECO:0000256|PROSITE-
KW ProRule:PRU00076};
KW EGF-like domain {ECO:0000256|ARBA:ARBA00022536, ECO:0000256|PROSITE-
KW ProRule:PRU00076}; Reference proteome {ECO:0000313|Proteomes:UP000087266};
KW Signal {ECO:0000256|ARBA:ARBA00022729, ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..25
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 26..355
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5010197283"
FT DOMAIN 137..179
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DISULFID 169..178
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
SQ SEQUENCE 355 AA; 39405 MW; 3CE7C0465491FC63 CRC64;
MLSINQLLWL FCSLAFILLS QCTYAKYIKS SCNTCKQIAD NFSKGLDRTK KQNFGGGNTA
WEERALSKYE TSEIRLVEIL ENLCDSSSFD CNHMVEEHED HFETWWFKRQ NKHPDLYKWF
CIDTIKVCCS TGTFGPDCNA CVAGSERPCH GNGVCDGDGT QGGNGRCNCD HGYKGEFCLD
CMDGYFNEIR NDTFSLCTEC HTSCKTCSGL TNEDCEKCKT GWGEDDEGTC LDVNECLNDP
PLCKEDQYCL NTDGSFSCKG CDKVCSGCTG AGPDKCQSCA PGYQDTEGTC TDVNECEQTD
AVCTAENQEC VNNKGSYVCI CASRYEELEG VCVKIPESEE NEAETVKSPE EHEDL
//
