ID   A0A1S3SF99_SALSA        Unreviewed;       619 AA.
AC   A0A1S3SF99;
DT   12-APR-2017, integrated into UniProtKB/TrEMBL.
DT   12-APR-2017, sequence version 1.
DT   27-MAR-2024, entry version 22.
DE   SubName: Full=GRAM domain-containing protein 4-like isoform X2 {ECO:0000313|RefSeq:XP_014063008.1};
GN   Name=LOC106609111 {ECO:0000313|RefSeq:XP_014063008.1};
OS   Salmo salar (Atlantic salmon).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Protacanthopterygii; Salmoniformes;
OC   Salmonidae; Salmoninae; Salmo.
OX   NCBI_TaxID=8030 {ECO:0000313|Proteomes:UP000087266, ECO:0000313|RefSeq:XP_014063008.1};
RN   [1] {ECO:0000313|RefSeq:XP_014063008.1}
RP   IDENTIFICATION.
RC   TISSUE=Muscle {ECO:0000313|RefSeq:XP_014063008.1};
RG   RefSeq;
RL   Submitted (NOV-2023) to UniProtKB.
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DR   RefSeq; XP_014063008.1; XM_014207533.1.
DR   AlphaFoldDB; A0A1S3SF99; -.
DR   GeneID; 106609111; -.
DR   OrthoDB; 3028864at2759; -.
DR   Proteomes; UP000087266; Chromosome ssa07.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0006915; P:apoptotic process; IEA:InterPro.
DR   CDD; cd13221; PH-GRAM_GRAMDC4; 1.
DR   Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 1.
DR   InterPro; IPR004182; GRAM.
DR   InterPro; IPR037847; GRAMDC4.
DR   InterPro; IPR037845; GRAMDC4_PH-GRAM.
DR   InterPro; IPR011993; PH-like_dom_sf.
DR   PANTHER; PTHR37402; GRAM DOMAIN-CONTAINING PROTEIN 4; 1.
DR   PANTHER; PTHR37402:SF1; GRAM DOMAIN-CONTAINING PROTEIN 4; 1.
DR   Pfam; PF02893; GRAM; 1.
DR   SMART; SM00568; GRAM; 1.
PE   4: Predicted;
KW   Coiled coil {ECO:0000256|SAM:Coils}; Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000087266};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        284..304
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          481..561
FT                   /note="GRAM"
FT                   /evidence="ECO:0000259|SMART:SM00568"
FT   REGION          162..193
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          112..155
FT                   /evidence="ECO:0000256|SAM:Coils"
SQ   SEQUENCE   619 AA;  70623 MW;  080576DFD3CF954E CRC64;
     MKLCYDLRAG IAVHHAKVKP PTRGVLNMLK RLDKIRFRGQ KRDDFLDLAE SPNGSDNECS
     DDILLRTKPS LKTQDTEELG DPAGSGALTM AAAFQDFQRS ESDRLNEMKG HLEIALLEKH
     FLQEELRKLR EETNVEKIKE ELERERGKRI DLELRMNEVL KSSLEDSPPQ PARKPPSPTP
     AANGKDTDKE KPPQGETLYL RAWRWLYDRV GVYIEDFRFV PEENTVEAEE PLSAKRLTEN
     MRRLKRGARP VTNFMRNLSA LSNWHSVYTS AISFIIYMNA AWHGWAIPMF LFLAILRLSL
     NYLIAKGWRI QWSIVPDITD PIEPSKDDLT VSEKFQLVLD VAQKAQNLFG KMADVLEKIK
     NLFMWVQPEI TQKLYISLWV AFLSSCILPF KLVGFMIGLY AGIKFFIIDF LFKSCPKLRD
     KYDTPHIDWN NLPTDPQLKE RTNATMSRRI QPVVARGSLA TVPCGVNLDG DSARIHSTKK
     GAFHEIFNVS ENERPLPVCD NGWRCCLINR DRKMPTDYIR NGMLYVTENY LCFESSSSKS
     AASKKNKVIK LVDITDIQKY KVLSVLPGSG MGISIATPST QKPLVFGAMI HRDEAFEAIF
     TQYMKIITTS RPPSGSPEL
//