ID   A0A1S3SHS1_SALSA        Unreviewed;       640 AA.
AC   A0A1S3SHS1;
DT   12-APR-2017, integrated into UniProtKB/TrEMBL.
DT   12-APR-2017, sequence version 1.
DT   27-MAR-2024, entry version 35.
DE   SubName: Full=Aryl hydrocarbon receptor nuclear translocator-like protein 2 isoform X1 {ECO:0000313|RefSeq:XP_014063876.1};
GN   Name=LOC106609509 {ECO:0000313|RefSeq:XP_014063876.1};
OS   Salmo salar (Atlantic salmon).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Protacanthopterygii; Salmoniformes;
OC   Salmonidae; Salmoninae; Salmo.
OX   NCBI_TaxID=8030 {ECO:0000313|Proteomes:UP000087266, ECO:0000313|RefSeq:XP_014063876.1};
RN   [1] {ECO:0000313|RefSeq:XP_014063876.1}
RP   IDENTIFICATION.
RC   TISSUE=Muscle {ECO:0000313|RefSeq:XP_014063876.1};
RG   RefSeq;
RL   Submitted (NOV-2023) to UniProtKB.
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DR   RefSeq; XP_014063876.1; XM_014208401.1.
DR   AlphaFoldDB; A0A1S3SHS1; -.
DR   STRING; 8030.ENSSSAP00000020377; -.
DR   PaxDb; 8030-ENSSSAP00000020377; -.
DR   GeneID; 106609509; -.
DR   KEGG; sasa:106609509; -.
DR   OMA; ETYRYCT; -.
DR   OrthoDB; 2872674at2759; -.
DR   Proteomes; UP000087266; Chromosome ssa07.
DR   Bgee; ENSSSAG00000009920; Expressed in pharyngeal gill and 14 other cell types or tissues.
DR   GO; GO:0005737; C:cytoplasm; IEA:InterPro.
DR   GO; GO:0005634; C:nucleus; IEA:InterPro.
DR   GO; GO:0005667; C:transcription regulator complex; IEA:InterPro.
DR   GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0046983; F:protein dimerization activity; IEA:InterPro.
DR   CDD; cd00130; PAS; 2.
DR   Gene3D; 4.10.280.10; Helix-loop-helix DNA-binding domain; 1.
DR   Gene3D; 3.30.450.20; PAS domain; 2.
DR   InterPro; IPR011598; bHLH_dom.
DR   InterPro; IPR036638; HLH_DNA-bd_sf.
DR   InterPro; IPR001067; Nuc_translocat.
DR   InterPro; IPR000014; PAS.
DR   InterPro; IPR035965; PAS-like_dom_sf.
DR   InterPro; IPR013767; PAS_fold.
DR   NCBIfam; TIGR00229; sensory_box; 1.
DR   PANTHER; PTHR23042:SF48; ARYL HYDROCARBON RECEPTOR NUCLEAR TRANSLOCATOR-LIKE PROTEIN 2; 1.
DR   PANTHER; PTHR23042; CIRCADIAN PROTEIN CLOCK/ARNT/BMAL/PAS; 1.
DR   Pfam; PF00010; HLH; 1.
DR   Pfam; PF00989; PAS; 1.
DR   Pfam; PF14598; PAS_11; 1.
DR   PRINTS; PR00785; NCTRNSLOCATR.
DR   SMART; SM00353; HLH; 1.
DR   SMART; SM00091; PAS; 2.
DR   SUPFAM; SSF47459; HLH, helix-loop-helix DNA-binding domain; 1.
DR   SUPFAM; SSF55785; PYP-like sensor domain (PAS domain); 2.
DR   PROSITE; PS50888; BHLH; 1.
DR   PROSITE; PS50112; PAS; 2.
PE   4: Predicted;
KW   Activator {ECO:0000256|ARBA:ARBA00023159};
KW   Receptor {ECO:0000313|RefSeq:XP_014063876.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000087266}.
FT   DOMAIN          99..152
FT                   /note="BHLH"
FT                   /evidence="ECO:0000259|PROSITE:PS50888"
FT   DOMAIN          173..238
FT                   /note="PAS"
FT                   /evidence="ECO:0000259|PROSITE:PS50112"
FT   DOMAIN          371..420
FT                   /note="PAS"
FT                   /evidence="ECO:0000259|PROSITE:PS50112"
FT   REGION          1..36
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          57..95
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          550..594
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        550..593
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   640 AA;  71290 MW;  E9CC8674B75032EF CRC64;
     MSKENLAAGG NDGTADKRTG PLQLGETKSL PVSRPDVITP HLERALHDAI TPHLAGAMPI
     QELSRKRKGD VDNREDGDAQ VEEEQSRSED DDQQVKMKCF REPHSQIEKR RRDKMNTLID
     ELSAMIPSCN PMARKLDKLT VLRMAVQHLK ALKAGASSSF TDVNYKRKPS FLPQDDLKHL
     VLTAADGFLF VVSCDRGKIL FTSESVSKFL NYSRLELIGQ SLFDYVHPKD ISKVKEQLSA
     SGLYPRERLI DAKTGLQVQD RPVGAVHLCT GAWRSFFCRM KHSRTVMKTE DKTIQPSSSK
     KKESQRYCTV HCTGYMRSWP STQLDTESDD NEFSHLSCLV AVCRVHPNNA CQPSLEVKVK
     PTQFVTRFAI DGKFTFVDQQ ATTVLGYLPQ ELLGTSCYEY FHQDDLQHLA ETHRKVLRSK
     EKIETSCYKF KTKHGSLVML QSQWFSFINP WTKEIEFIVS TNRVLGPSHT EAEQPSSSKL
     LDEESKRTIL IPGISSGMAT MIYAGSIGTQ IANELLDSNR VNCSPSNGTS SPFCPPQDRF
     PMVSSHANMP NEEVTDSDTV SKPRLQSASK GATYAGSNTH MDTARSPPGE SSQMDLDSMV
     GPGLGILSND EAAMAVIMSL LETDANLGDA VDFDNMHWSH
//