ID A0A1S3SJ64_SALSA Unreviewed; 2279 AA.
AC A0A1S3SJ64;
DT 12-APR-2017, integrated into UniProtKB/TrEMBL.
DT 12-APR-2017, sequence version 1.
DT 27-MAR-2024, entry version 27.
DE SubName: Full=ATP-binding cassette sub-family A member 1-like isoform X2 {ECO:0000313|RefSeq:XP_014064380.1};
GN Name=LOC106609880 {ECO:0000313|RefSeq:XP_014064380.1};
OS Salmo salar (Atlantic salmon).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Protacanthopterygii; Salmoniformes;
OC Salmonidae; Salmoninae; Salmo.
OX NCBI_TaxID=8030 {ECO:0000313|Proteomes:UP000087266, ECO:0000313|RefSeq:XP_014064380.1};
RN [1] {ECO:0000313|RefSeq:XP_014064380.1}
RP IDENTIFICATION.
RC TISSUE=Muscle {ECO:0000313|RefSeq:XP_014064380.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR RefSeq; XP_014064380.1; XM_014208905.1.
DR STRING; 8030.ENSSSAP00000072463; -.
DR PaxDb; 8030-ENSSSAP00000072463; -.
DR GeneID; 106609880; -.
DR OMA; PFATWSE; -.
DR OrthoDB; 6951at2759; -.
DR Proteomes; UP000087266; Chromosome ssa08.
DR Bgee; ENSSSAG00000006489; Expressed in semen and 14 other cell types or tissues.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0140359; F:ABC-type transporter activity; IEA:InterPro.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR CDD; cd03263; ABC_subfamily_A; 2.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR013525; ABC2_TM.
DR InterPro; IPR003439; ABC_transporter-like_ATP-bd.
DR InterPro; IPR017871; ABC_transporter-like_CS.
DR InterPro; IPR026082; ABCA.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR19229; ATP-BINDING CASSETTE TRANSPORTER SUBFAMILY A ABCA; 1.
DR PANTHER; PTHR19229:SF34; PHOSPHOLIPID-TRANSPORTING ATPASE ABCA1; 1.
DR Pfam; PF12698; ABC2_membrane_3; 2.
DR Pfam; PF00005; ABC_tran; 2.
DR SMART; SM00382; AAA; 2.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 2.
DR PROSITE; PS00211; ABC_TRANSPORTER_1; 1.
DR PROSITE; PS50893; ABC_TRANSPORTER_2; 2.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840,
KW ECO:0000313|RefSeq:XP_014064380.1};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000087266};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 22..42
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 647..666
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 686..710
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 722..745
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 751..771
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 783..802
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1367..1389
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1672..1694
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1714..1739
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1751..1771
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1783..1805
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1870..1889
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 904..1135
FT /note="ABC transporter"
FT /evidence="ECO:0000259|PROSITE:PS50893"
FT DOMAIN 1929..2161
FT /note="ABC transporter"
FT /evidence="ECO:0000259|PROSITE:PS50893"
SQ SEQUENCE 2279 AA; 255239 MW; 8BDBDC370C78BB49 CRC64;
MAISTQLGLL LWKNFTYRRR QTLQLIIEII WPLFIFFILI SVRMHYPPYE QHECHFPNKA
MPSAGTLPWV QGIICNANNP CFRHPTPGES PGLVGNFNDS IISRLFIDAK KILLYSQNDK
SFEGYKVLVR ALGKLQSNTA GFKLKDFLRD KETLSSFLHR NASLSHHAVQ QIVEADLNLE
KVLIGGFGVH LRDMCNTTSL EEFVTISDKN VSRLTQDIIC KASPDWLNKA QDHFLSNLDF
LKPIRKDVKS DPEVVQKVSA ATDGLLESLG ALAVELASMK SWKEMRNEIH YLTANATGSP
SHMYQAVSRI VCGHPEGGGL KIKSLNWYED NNYKALFGNH GGNGSDDEPV SAYDNTSTPY
CNSMMRSLEA SPISRMIWRA LKPLLMGKIL YTPDTPATQR IIHEMNKTFQ ELGILRDLGG
MWEEMRPKVW NFMESSEEMD LFRTLLQNNA SARFFNDRLA GTEWKVEDVS RFLTKAAEDK
RPAGSAYTWR EVFNETDDAI KTISRFMECV NLDKLEPVAN EERLVNKSMG LLDNQKFWAG
IVFPDIARSN SSDLPGNVNY KIRMDIDNVE RTNKIKDGYW DPGPRADPFE DLRYIWGGFS
YLQDVIEQGI IRAVTGSKEK TGVYIQQMPY PCYVDDMFLR VMSRSMPLFM TLAWMYSVAL
IIKGVVYEKE ARLKETMRIM GLDNGILWLS WFISSLIPLL ISASLLVVIL KMGNLLPYSD
PCVVFLFLAS FAVVTIMQCF LISTIFSRAN LAAACGGIIY FTLYLPYVLC VAWQDYVGFG
AKVIVSLLSP VAFGFGCEYF ALFEEQGVGI QWSNLLSSPL EEDSYSLTTS ICLMLFDSFL
YGVMTWYIEA VFPGQYGIPR PWYFPFTKSY WCGEKQGKNI QERKEGNAEA VCIEEEPSHI
EPGVYIKNLV KVYSHGNKLA VDGLTLGFYE GQITSFLGHN GAGKTTTMSI LTGLFPPTSG
TAYILGKDIR SELSAIRQNL GVCPQHNVLF SMLTVEEHIW FYARLKGLSE EKVKAEMEQI
VNDIGLPHKR QCRSNTLSGG MQRKLSVALA FVGGSKVVIL DEPTAGVDPY ARRGIWDLLL
KYRPGRTIIL STHHMDEADI LGDRIAIISH GKLCCVGSSL FLKTQLGTGY YLTLVKRDLD
LTLSSCRNSS SSSVSYSKKV GLPQPQPQAL TVLKEDSVSE SSSDAGLGSE PESEATTIDV
TMISNVIFKH VPAARLVEDL GHELTYVLPY KAAKGGAFVE LFHEIDDRLS DLGISSYGIS
DTTLEEIFLK VAEDSGVDVA ELPNSDGTIP ARRHRRHAFG DHQSCLKPFN EDDAFDFNDS
EESRETDWLG GSDGKGSYQV KGWRLIRQQF VALIWKRFLY ARRSRKGFFA QIVLPAVFVC
IALVFSLIVP PFGKYPSLEL EPGMYEEQFT FISNDAPEDA NTNKLLGALT NYDGFDSRCN
SPHAPCNTLD DEWVVPEVPE SVRDIFMNGN WSMENPSPLC ECSCEGRKKM LPECPAGAGG
LPPPQVKISD KGTLQNLTGR NISDYLVKTY AQIIGKSLKN KISVNEFRYG GFSLGARNTQ
LLPPGDDIDQ AISEIRRRFH LERGTAADRF LASLSSFIQG LDTKNNVKIW FNNKGWHSIG
SFLNVMNNGI LRASLPAGQD PREYGIRAFN HPLNLTKEQL SQVALMTTSV DVLVSICVIF
AMSFVPASFV VFLIQERVNK AKHMQFISGV QPFLYWLSNF IWDMCNYIVP ATLVIIIFIC
FQQDAYVSST NLPVLALLLL FYGWSITPLM YPASFFFKIP STAYVVLTSV NILIGINGSV
STFVLELFGS NEIGGINDIL KNVFLIFPHF CLGRGLIDMV KNQAMADALE RFGENRFRSP
LAWDMVGKNL FAMAVQGVVF FTITVLIQYR FCIKARSMST DQKPIGEEDE DVARERQRIL
GGGGQSDILE LKQLTKVYNR KQKPAVDRLC VGIPPGECFG LLGVNGAGKT STFKMLTGDS
IVTSGEAYLA GKSVLTEINE VHQNMGYCPQ FDAINDLLTG REHLEFYAIL RGVPEKEVCE
VAEWGIRKLG LIKYVDKAAG SYSGGNMRKL STAMALIGGP PVVFLDEPTT GMDPKARRAL
WNCILSIVKE GRSVVLTSHS MEECEALCTR MAIMVNGRFR CLGSVQHLKN RFGDGYTIIL
RVAGPDPDLR PVMEFIEKEL PGSTLKEKHR NMLQYQLSSS KTSLARIFSI LAKNKEWLHI
EDYSVSQTTL DQVFVNFAKD QSDEDHLKDI SMHKRDAVAV DITQLKSFLT DEKARESCV
//
