ID   A0A1S3SMC5_SALSA        Unreviewed;       658 AA.
AC   A0A1S3SMC5;
DT   12-APR-2017, integrated into UniProtKB/TrEMBL.
DT   12-APR-2017, sequence version 1.
DT   27-MAR-2024, entry version 31.
DE   RecName: Full=Protein Smaug homolog 1 {ECO:0000256|ARBA:ARBA00041183};
DE   AltName: Full=Sterile alpha motif domain-containing protein 4A {ECO:0000256|ARBA:ARBA00041298};
GN   Name=LOC106610612 {ECO:0000313|RefSeq:XP_014065494.1};
OS   Salmo salar (Atlantic salmon).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Protacanthopterygii; Salmoniformes;
OC   Salmonidae; Salmoninae; Salmo.
OX   NCBI_TaxID=8030 {ECO:0000313|Proteomes:UP000087266, ECO:0000313|RefSeq:XP_014065494.1};
RN   [1] {ECO:0000313|RefSeq:XP_014065494.1}
RP   IDENTIFICATION.
RC   TISSUE=Muscle {ECO:0000313|RefSeq:XP_014065494.1};
RG   RefSeq;
RL   Submitted (NOV-2023) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
CC       Synapse, synaptosome {ECO:0000256|ARBA:ARBA00034102}.
CC   -!- SIMILARITY: Belongs to the SMAUG family.
CC       {ECO:0000256|ARBA:ARBA00008232}.
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DR   RefSeq; XP_014065494.1; XM_014210019.1.
DR   AlphaFoldDB; A0A1S3SMC5; -.
DR   GeneID; 106610612; -.
DR   OrthoDB; 1351201at2759; -.
DR   Proteomes; UP000087266; Chromosome ssa09.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0043005; C:neuron projection; IEA:UniProtKB-KW.
DR   GO; GO:0045202; C:synapse; IEA:UniProtKB-SubCell.
DR   GO; GO:0003723; F:RNA binding; IEA:InterPro.
DR   GO; GO:0030371; F:translation repressor activity; IEA:InterPro.
DR   GO; GO:0043488; P:regulation of mRNA stability; IEA:InterPro.
DR   CDD; cd09557; SAM_Smaug; 1.
DR   Gene3D; 1.25.40.170; Smaug, PHAT domain; 1.
DR   Gene3D; 1.10.150.50; Transcription Factor, Ets-1; 1.
DR   InterPro; IPR037093; PHAT_dom_sf.
DR   InterPro; IPR001660; SAM.
DR   InterPro; IPR013761; SAM/pointed_sf.
DR   InterPro; IPR037634; Smaug_SAM.
DR   PANTHER; PTHR12515:SF8; PROTEIN SMAUG HOMOLOG 1; 1.
DR   PANTHER; PTHR12515; STERILE ALPHA MOTIF DOMAIN CONTAINING PROTEIN 4-RELATED; 1.
DR   Pfam; PF00536; SAM_1; 1.
DR   SMART; SM00454; SAM; 1.
DR   SUPFAM; SSF47769; SAM/Pointed domain; 1.
PE   3: Inferred from homology;
KW   Reference proteome {ECO:0000313|Proteomes:UP000087266};
KW   Repressor {ECO:0000256|ARBA:ARBA00022491};
KW   Synapse {ECO:0000256|ARBA:ARBA00022599};
KW   Synaptosome {ECO:0000256|ARBA:ARBA00022599};
KW   Translation regulation {ECO:0000256|ARBA:ARBA00022845}.
FT   DOMAIN          290..353
FT                   /note="SAM"
FT                   /evidence="ECO:0000259|SMART:SM00454"
FT   REGION          157..187
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          207..237
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          388..426
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          546..574
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        173..187
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        210..232
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        389..407
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   658 AA;  71934 MW;  3D24053E8E6B2B1B CRC64;
     MMFRDQVGVL GSWFKGWNEC EQTVALLSLL KRVSRTQARF LQLCLEHSLA ECTELHVLEG
     EANNPVVISQ WQGEPKERVI SLVLTHLPLL KPGNVEAKGE YMRLLPRILA HTIDHGRHLE
     ESRQLLSYAL IHPATSLDDR AALALWLNHL EERAAARGDS LERPPPVPAS LHQTPPSTHS
     LSGSSWSSSG SHLGQLYHHQ RYGSDDRLNG WQGSRDSGLG SGWHQQQQGH GGCENGGHLA
     LYPSSSVPGS INTVGTGGSI FPLDYCPGVA QRPPKQHPGP LGTNRVGQGG LPQLYNDVPA
     WLKSLRLHKY AALFSTMTYD EMMSLTEQQL ESQNVTKGAR HKIVISIQKL KERQKMLRCL
     EKDVLEGGNL RGPLAELHQM ILTPIKAVAS DESSPSSPSS TAHRPLLSPE GKSSAAPGGE
     GETGTTLIAE GDIPGQFTRV MGKVCTQLLV SRPDEENISS YLQLIDKCLL HEAFTETQKK
     RLLSWKQQVQ KLIRSFPRKT LLDMAGYRAQ RSSSRGFSQS NSLPTAGCVG GSSSVSAARR
     SLRQFQMPSR SLPGARPGLL GPTPHSTSST PTGLKQGRQG LWFANPGGSN SMPSRTHSSV
     QRTRSLPVHT TPHTMVMFQQ SDLQVPVTEP DINNRLESLC LSMTEHALGD GVDRTSTI
//