ID A0A1S3SMY0_SALSA Unreviewed; 328 AA.
AC A0A1S3SMY0;
DT 12-APR-2017, integrated into UniProtKB/TrEMBL.
DT 12-APR-2017, sequence version 1.
DT 27-MAR-2024, entry version 26.
DE SubName: Full=Left-right determination factor 2-like isoform X2 {ECO:0000313|RefSeq:XP_014065700.1};
GN Name=LOC106610717 {ECO:0000313|RefSeq:XP_014065700.1};
OS Salmo salar (Atlantic salmon).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Protacanthopterygii; Salmoniformes;
OC Salmonidae; Salmoninae; Salmo.
OX NCBI_TaxID=8030 {ECO:0000313|Proteomes:UP000087266, ECO:0000313|RefSeq:XP_014065700.1};
RN [1] {ECO:0000313|RefSeq:XP_014065700.1}
RP IDENTIFICATION.
RC TISSUE=Muscle {ECO:0000313|RefSeq:XP_014065700.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the TGF-beta family.
CC {ECO:0000256|ARBA:ARBA00006656, ECO:0000256|RuleBase:RU000354}.
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DR RefSeq; XP_014065700.1; XM_014210225.1.
DR AlphaFoldDB; A0A1S3SMY0; -.
DR OrthoDB; 5391376at2759; -.
DR Proteomes; UP000087266; Chromosome ssa09.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-KW.
DR GO; GO:0008083; F:growth factor activity; IEA:UniProtKB-KW.
DR GO; GO:0005160; F:transforming growth factor beta receptor binding; IEA:InterPro.
DR CDD; cd13758; TGF_beta_LEFTY1_2; 1.
DR Gene3D; 2.60.120.970; -; 1.
DR Gene3D; 2.10.90.10; Cystine-knot cytokines; 1.
DR InterPro; IPR029034; Cystine-knot_cytokine.
DR InterPro; IPR003942; LRDF.
DR InterPro; IPR001839; TGF-b_C.
DR InterPro; IPR001111; TGF-b_propeptide.
DR InterPro; IPR015615; TGF-beta-rel.
DR InterPro; IPR017948; TGFb_CS.
DR PANTHER; PTHR11848:SF226; LEFT-RIGHT DETERMINATION FACTOR; 1.
DR PANTHER; PTHR11848; TGF-BETA FAMILY; 1.
DR Pfam; PF00019; TGF_beta; 1.
DR Pfam; PF00688; TGFb_propeptide; 1.
DR PIRSF; PIRSF037402; TGFb4; 1.
DR PRINTS; PR01427; TGFBETA4.
DR SMART; SM00204; TGFB; 1.
DR SUPFAM; SSF57501; Cystine-knot cytokines; 1.
DR PROSITE; PS00250; TGF_BETA_1; 1.
DR PROSITE; PS51362; TGF_BETA_2; 1.
PE 3: Inferred from homology;
KW Growth factor {ECO:0000256|ARBA:ARBA00023030,
KW ECO:0000256|RuleBase:RU000354};
KW Reference proteome {ECO:0000313|Proteomes:UP000087266};
KW Secreted {ECO:0000256|ARBA:ARBA00022525}.
FT DOMAIN 221..322
FT /note="TGF-beta family profile"
FT /evidence="ECO:0000259|PROSITE:PS51362"
SQ SEQUENCE 328 AA; 37600 MW; DFA125AE2ED033C7 CRC64;
MLQRLGLKEL PRIHKRDLEN LVVPSHIRNT YLTLLKLHHE RRRRSLPSLA GILRGISGNA
DISGEILYSD ATRERLVFDM EARVPANSEV TMAELRLYQN APHKLHLAGR KSQKQDNNAR
VSVYWVEVLE NGANRSSLVD SRLVPIYETG WKGFDVTQAV HYWSKGRREA PLRLELRVEG
ERPGSYAAEM AKSVRFTAQD PSDQSTGKPE LLFYTLNLEE YGSRGDCQSS KPNGICCRED
YFINFRELTW TQYWVIEPAG YQSFRCAGGC KQPKRRYGYG ERRCAATENA PLPIMYLVKK
GDYTEIEVAE FPNMIVEKCR CTMDNVSV
//
