ID A0A1S3SNE8_SALSA Unreviewed; 349 AA.
AC A0A1S3SNE8;
DT 12-APR-2017, integrated into UniProtKB/TrEMBL.
DT 12-APR-2017, sequence version 1.
DT 27-MAR-2024, entry version 29.
DE SubName: Full=Homeobox protein Nkx-2.4-like isoform X1 {ECO:0000313|RefSeq:XP_014065867.1};
GN Name=LOC106610802 {ECO:0000313|RefSeq:XP_014065867.1};
OS Salmo salar (Atlantic salmon).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Protacanthopterygii; Salmoniformes;
OC Salmonidae; Salmoninae; Salmo.
OX NCBI_TaxID=8030 {ECO:0000313|Proteomes:UP000087266, ECO:0000313|RefSeq:XP_014065867.1};
RN [1] {ECO:0000313|RefSeq:XP_014065867.1}
RP IDENTIFICATION.
RC TISSUE=Muscle {ECO:0000313|RefSeq:XP_014065867.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123,
CC ECO:0000256|PROSITE-ProRule:PRU00108, ECO:0000256|RuleBase:RU000682}.
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DR RefSeq; XP_014065867.1; XM_014210392.1.
DR AlphaFoldDB; A0A1S3SNE8; -.
DR PaxDb; 8030-ENSSSAP00000038241; -.
DR GeneID; 106610802; -.
DR KEGG; sasa:106610802; -.
DR OMA; VSQFPHS; -.
DR OrthoDB; 461623at2759; -.
DR Proteomes; UP000087266; Chromosome ssa09.
DR Bgee; ENSSSAG00000043465; Expressed in brain and 1 other cell type or tissue.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0000981; F:DNA-binding transcription factor activity, RNA polymerase II-specific; IEA:InterPro.
DR CDD; cd00086; homeodomain; 1.
DR Gene3D; 1.10.10.60; Homeodomain-like; 1.
DR InterPro; IPR009057; Homeobox-like_sf.
DR InterPro; IPR017970; Homeobox_CS.
DR InterPro; IPR001356; Homeobox_dom.
DR InterPro; IPR020479; Homeobox_metazoa.
DR PANTHER; PTHR24340; HOMEOBOX PROTEIN NKX; 1.
DR PANTHER; PTHR24340:SF40; HOMEOBOX PROTEIN NKX-2.4; 1.
DR Pfam; PF00046; Homeodomain; 1.
DR PRINTS; PR00024; HOMEOBOX.
DR SMART; SM00389; HOX; 1.
DR SUPFAM; SSF46689; Homeodomain-like; 1.
DR PROSITE; PS00027; HOMEOBOX_1; 1.
DR PROSITE; PS50071; HOMEOBOX_2; 1.
PE 4: Predicted;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125, ECO:0000256|PROSITE-
KW ProRule:PRU00108};
KW Homeobox {ECO:0000256|ARBA:ARBA00023155, ECO:0000256|PROSITE-
KW ProRule:PRU00108};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242, ECO:0000256|PROSITE-
KW ProRule:PRU00108}; Reference proteome {ECO:0000313|Proteomes:UP000087266}.
FT DOMAIN 158..218
FT /note="Homeobox"
FT /evidence="ECO:0000259|PROSITE:PS50071"
FT DNA_BIND 160..219
FT /note="Homeobox"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00108"
FT REGION 218..291
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 222..242
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 254..291
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 349 AA; 38733 MW; AEE8326CE842A131 CRC64;
MSLSPKHTTP FSVTDILSPI EETYKKFSGM DGAGNLTSPL GAYRQPQVSQ TGMQQHSMGH
NATVATTYHM PHTVSQFSHS AMGGYCNGSI GNMGDLPSYQ ETMRNSAAAT GWYGANTDPR
YSTISRFMGP STGMNMTGMG TLTGMGDASR SMPPLHAAPR RKRRVLFSQA QVYELERRFK
QQKYLSAPER EHLASMIHLT PTQVKIWFQN HRYKMKRQAK DKAAQQLQQD SNLCQQQQSP
RRVAVPVLVK DGKPCQNGSN TPTPNQQQVQ QQQQQQQHNG SGVLPASSNG INQHQNQQVH
SLVQAQDLEE ISPSPPSLHS QINMAQIDTS AIDYTNNMVS SNLLYGRTW
//
