ID A0A1S3SUV0_SALSA Unreviewed; 501 AA.
AC A0A1S3SUV0;
DT 12-APR-2017, integrated into UniProtKB/TrEMBL.
DT 12-APR-2017, sequence version 1.
DT 27-MAR-2024, entry version 31.
DE SubName: Full=Ras-GEF domain-containing family member 1C-like isoform X2 {ECO:0000313|RefSeq:XP_014068121.1};
GN Name=LOC106611945 {ECO:0000313|RefSeq:XP_014068121.1};
OS Salmo salar (Atlantic salmon).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Protacanthopterygii; Salmoniformes;
OC Salmonidae; Salmoninae; Salmo.
OX NCBI_TaxID=8030 {ECO:0000313|Proteomes:UP000087266, ECO:0000313|RefSeq:XP_014068121.1};
RN [1] {ECO:0000313|RefSeq:XP_014068121.1}
RP IDENTIFICATION.
RC TISSUE=Muscle {ECO:0000313|RefSeq:XP_014068121.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
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DR RefSeq; XP_014068121.1; XM_014212646.1.
DR AlphaFoldDB; A0A1S3SUV0; -.
DR STRING; 8030.ENSSSAP00000028492; -.
DR PaxDb; 8030-ENSSSAP00000028492; -.
DR GeneID; 106611945; -.
DR OrthoDB; 7992at2759; -.
DR Proteomes; UP000087266; Chromosome ssa09.
DR GO; GO:0005085; F:guanyl-nucleotide exchange factor activity; IEA:UniProtKB-KW.
DR GO; GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
DR CDD; cd00155; RasGEF; 1.
DR CDD; cd06224; REM; 1.
DR Gene3D; 1.10.840.10; Ras guanine-nucleotide exchange factors catalytic domain; 1.
DR Gene3D; 1.20.870.10; Son of sevenless (SoS) protein Chain: S domain 1; 1.
DR InterPro; IPR008937; Ras-like_GEF.
DR InterPro; IPR000651; Ras-like_Gua-exchang_fac_N.
DR InterPro; IPR023578; Ras_GEF_dom_sf.
DR InterPro; IPR001895; RASGEF_cat_dom.
DR InterPro; IPR036964; RASGEF_cat_dom_sf.
DR PANTHER; PTHR23113; GUANINE NUCLEOTIDE EXCHANGE FACTOR; 1.
DR PANTHER; PTHR23113:SF186; RAS-GEF DOMAIN-CONTAINING FAMILY MEMBER 1C; 1.
DR Pfam; PF00617; RasGEF; 1.
DR Pfam; PF00618; RasGEF_N; 1.
DR SMART; SM00147; RasGEF; 1.
DR SUPFAM; SSF48366; Ras GEF; 1.
DR PROSITE; PS50009; RASGEF_CAT; 1.
DR PROSITE; PS50212; RASGEF_NTER; 1.
PE 4: Predicted;
KW Guanine-nucleotide releasing factor {ECO:0000256|ARBA:ARBA00022658,
KW ECO:0000256|PROSITE-ProRule:PRU00168};
KW Reference proteome {ECO:0000313|Proteomes:UP000087266}.
FT DOMAIN 49..179
FT /note="N-terminal Ras-GEF"
FT /evidence="ECO:0000259|PROSITE:PS50212"
FT DOMAIN 223..472
FT /note="Ras-GEF"
FT /evidence="ECO:0000259|PROSITE:PS50009"
FT REGION 19..49
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 501 AA; 56736 MW; F896BF4BD74E0DC5 CRC64;
MPQTVFPAAG TMFTPSGFSP HLASTCSEAD PEEEEGPEEA RGPGACAADG PPITSASLDT
LIQHLVPTAD YYPEKAYVFT FLLSARLFIS PPELLVRLCD TCIKQQQLDQ SPLDTAKVRK
FGPKILQLLT EWTETFPTDF REEKMVGLFK DIIHRIAPCD EAYWKTLNQV LQTLNQKLAA
IAQGEESIVK VNASSVSSIS DKLVGFKTKP PPIQKDILSI CNDPYTLAQQ LTHVELEHLS
HIGPEEFVQA FVQKDPLDST QPCFSEQKKK TTNLEAYVRW FNRLCYLVAT EICMPAKKKQ
RAQVIEFFID VARECFNIGN FNSLMAIISG MNMSPVSRLK KTWGKAKTAK FFILEHQMDP
TGNFYNYRTA LRGAVHRSQT ANSIREKIVI PFFSLLIKDI YFLNEGCANR LPNGHVHFAK
FVELARQVGE FMTWKQIECP FETDRSILHY LHTAPIFSED GLYLASYESE SPENQVEKDR
WKALRSNILV KTKELKEHHG S
//
