ID A0A1S3SWB5_SALSA Unreviewed; 173 AA.
AC A0A1S3SWB5;
DT 12-APR-2017, integrated into UniProtKB/TrEMBL.
DT 12-APR-2017, sequence version 1.
DT 27-MAR-2024, entry version 25.
DE SubName: Full=Caltractin-like isoform X1 {ECO:0000313|RefSeq:XP_014068632.1};
GN Name=LOC106612201 {ECO:0000313|RefSeq:XP_014068632.1};
OS Salmo salar (Atlantic salmon).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Protacanthopterygii; Salmoniformes;
OC Salmonidae; Salmoninae; Salmo.
OX NCBI_TaxID=8030 {ECO:0000313|Proteomes:UP000087266, ECO:0000313|RefSeq:XP_014068632.1};
RN [1] {ECO:0000313|RefSeq:XP_014068632.1}
RP IDENTIFICATION.
RC TISSUE=Muscle {ECO:0000313|RefSeq:XP_014068632.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- FUNCTION: Calmodulin acts as part of a calcium signal transduction
CC pathway by mediating the control of a large number of enzymes, ion
CC channels, aquaporins and other proteins through calcium-binding.
CC Calcium-binding is required for the activation of calmodulin. Among the
CC enzymes to be stimulated by the calmodulin-calcium complex are a number
CC of protein kinases, such as myosin light-chain kinases and calmodulin-
CC dependent protein kinase type II (CaMK2), and phosphatases.
CC {ECO:0000256|ARBA:ARBA00037485}.
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DR RefSeq; XP_014068632.1; XM_014213157.1.
DR AlphaFoldDB; A0A1S3SWB5; -.
DR GeneID; 106612201; -.
DR KEGG; sasa:106612201; -.
DR OMA; REWEPHF; -.
DR OrthoDB; 67444at2759; -.
DR Proteomes; UP000087266; Chromosome ssa09.
DR Bgee; ENSSSAG00000060848; Expressed in brain and 2 other cell types or tissues.
DR GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR CDD; cd00051; EFh; 2.
DR Gene3D; 1.10.238.10; EF-hand; 3.
DR InterPro; IPR011992; EF-hand-dom_pair.
DR InterPro; IPR018247; EF_Hand_1_Ca_BS.
DR InterPro; IPR002048; EF_hand_dom.
DR PANTHER; PTHR23050; CALCIUM BINDING PROTEIN; 1.
DR PANTHER; PTHR23050:SF218; CENTRIN-1; 1.
DR Pfam; PF13499; EF-hand_7; 2.
DR SMART; SM00054; EFh; 4.
DR SUPFAM; SSF47473; EF-hand; 1.
DR PROSITE; PS00018; EF_HAND_1; 3.
DR PROSITE; PS50222; EF_HAND_2; 4.
PE 4: Predicted;
KW Calcium {ECO:0000256|ARBA:ARBA00022837};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000087266};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT DOMAIN 29..64
FT /note="EF-hand"
FT /evidence="ECO:0000259|PROSITE:PS50222"
FT DOMAIN 65..100
FT /note="EF-hand"
FT /evidence="ECO:0000259|PROSITE:PS50222"
FT DOMAIN 102..137
FT /note="EF-hand"
FT /evidence="ECO:0000259|PROSITE:PS50222"
FT DOMAIN 138..173
FT /note="EF-hand"
FT /evidence="ECO:0000259|PROSITE:PS50222"
FT REGION 1..29
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 173 AA; 19738 MW; 1F8885900475967B CRC64;
MATSVKRPSL GPVPPPKKKS SPKSELTEEL KQEIREAFEL FDTDASGHIE VKELKVAMRA
LGFEPKKEEI KRMMTEVDKD GTGKISFSDF LSVMTQKMAE KDSKEEILKA FRLFDDDETG
KISFRNLKRV AKELGENLTD EELQEMIEEA DRDGDGEVNQ GEFLRIMKKT SLY
//
