ID A0A1S3SXE9_SALSA Unreviewed; 774 AA.
AC A0A1S3SXE9;
DT 12-APR-2017, integrated into UniProtKB/TrEMBL.
DT 12-APR-2017, sequence version 1.
DT 27-MAR-2024, entry version 26.
DE SubName: Full=Leucine-rich repeat and calponin homology domain-containing protein 3 isoform X1 {ECO:0000313|RefSeq:XP_014069022.1};
GN Name=lrch3 {ECO:0000313|RefSeq:XP_014069022.1};
OS Salmo salar (Atlantic salmon).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Protacanthopterygii; Salmoniformes;
OC Salmonidae; Salmoninae; Salmo.
OX NCBI_TaxID=8030 {ECO:0000313|Proteomes:UP000087266, ECO:0000313|RefSeq:XP_014069022.1};
RN [1] {ECO:0000313|RefSeq:XP_014069022.1}
RP IDENTIFICATION.
RC TISSUE=Muscle {ECO:0000313|RefSeq:XP_014069022.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
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DR RefSeq; XP_014069022.1; XM_014213547.1.
DR AlphaFoldDB; A0A1S3SXE9; -.
DR STRING; 8030.ENSSSAP00000024544; -.
DR PaxDb; 8030-ENSSSAP00000024544; -.
DR KEGG; sasa:106612433; -.
DR OMA; HFGQTTS; -.
DR OrthoDB; 2956716at2759; -.
DR Proteomes; UP000087266; Chromosome ssa09.
DR Bgee; ENSSSAG00000018627; Expressed in head kidney and 15 other cell types or tissues.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR Gene3D; 1.10.418.10; Calponin-like domain; 1.
DR Gene3D; 3.80.10.10; Ribonuclease Inhibitor; 1.
DR InterPro; IPR001715; CH_dom.
DR InterPro; IPR036872; CH_dom_sf.
DR InterPro; IPR001611; Leu-rich_rpt.
DR InterPro; IPR003591; Leu-rich_rpt_typical-subtyp.
DR InterPro; IPR032675; LRR_dom_sf.
DR PANTHER; PTHR48051; -; 1.
DR PANTHER; PTHR48051:SF44; LEUCINE RICH REPEATS AND CALPONIN HOMOLOGY DOMAIN CONTAINING 3; 1.
DR Pfam; PF00307; CH; 1.
DR Pfam; PF00560; LRR_1; 1.
DR Pfam; PF13855; LRR_8; 1.
DR SMART; SM00033; CH; 1.
DR SMART; SM00364; LRR_BAC; 5.
DR SMART; SM00369; LRR_TYP; 5.
DR SUPFAM; SSF47576; Calponin-homology domain, CH-domain; 1.
DR SUPFAM; SSF52058; L domain-like; 1.
DR PROSITE; PS50021; CH; 1.
DR PROSITE; PS51450; LRR; 1.
PE 4: Predicted;
KW Leucine-rich repeat {ECO:0000256|ARBA:ARBA00022614};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000087266};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 749..770
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 624..737
FT /note="Calponin-homology (CH)"
FT /evidence="ECO:0000259|PROSITE:PS50021"
FT REGION 338..367
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 407..465
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 504..526
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 554..582
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 600..624
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 338..353
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 420..436
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 437..452
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 554..569
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 774 AA; 85286 MW; 6FA9986A7A1B68F1 CRC64;
MAASVLLSAE NTGLTFAVGN SGTVGAPGNG VGVPVPVPWN RSLDRALEEA SATGCLNLSG
RKLKEFPRSA ANHDLTDTTR ADLSRNRLPE LPLEVCMFVS LEHLQLYQNC LRSLPESLLN
LQALTYLNIS RNQLSTLPSP VCSLPLKVLI ACNNKLVSLP EELGQLRQLT ELDVSCNEIQ
TLPPQVGRLD SLRDLNIRRN HLARLPPELA ALPLVRLDFS CNKVTSIPVC YRNLRHLQSI
VLDNNPLQNP PAQICIKGMI HIFKYLNNEA SKTTPELPDY DRRPLAFGSC VEELYPGRPY
GALDSGFNSV DSGDKRWSGN EPTDELSDLP LRVAEITKEQ RQRREREEHR TTGSHSVTNG
TLEAELEQID FIDSCTGEEE EEEEEGRREV AETISLSSQF MAYIEHRVTR EGSPVKSNSS
RDLRTDDPRR HNSLQNRTAH DPASSASNQR GSVARVGPCG APGGGVERVR RMAQLAALRY
EEERQKSRSV QRDTVMTYVK HKAYQSPTKL SPTENENTYP SRRSTHTDDS ALFMSLSRSG
MSIDIVPTCL LQQGEDRSSS LSPTALQSPS YPGPVAPPFC QGPAQRPDSF LFRLIQKEEQ
RRGDGAAPRP EPEEVTPTQP QGPMGEEAAL VEQLRKNIES RLKVSLPSDL GAALTDGVVL
CHLANHVRPR SVPSIHVPSP AVPKLTMAKC RRNVENFLEA CRRIGVPQER LCTVEEVLDG
RGGCVYGTLG VLLSMAPPPL LMPSPPAQLA GFALFYLSIM SVLCALYCNL VPHL
//
