ID   A0A1S3T0R6_SALSA        Unreviewed;       420 AA.
AC   A0A1S3T0R6;
DT   12-APR-2017, integrated into UniProtKB/TrEMBL.
DT   12-APR-2017, sequence version 1.
DT   27-MAR-2024, entry version 28.
DE   RecName: Full=Protein FAM118B {ECO:0000256|ARBA:ARBA00014026};
GN   Name=LOC106612962 {ECO:0000313|RefSeq:XP_014070162.1};
OS   Salmo salar (Atlantic salmon).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Protacanthopterygii; Salmoniformes;
OC   Salmonidae; Salmoninae; Salmo.
OX   NCBI_TaxID=8030 {ECO:0000313|Proteomes:UP000087266, ECO:0000313|RefSeq:XP_014070162.1};
RN   [1] {ECO:0000313|RefSeq:XP_014070162.1}
RP   IDENTIFICATION.
RC   TISSUE=Muscle {ECO:0000313|RefSeq:XP_014070162.1};
RG   RefSeq;
RL   Submitted (NOV-2023) to UniProtKB.
CC   -!- FUNCTION: May play a role in Cajal bodies formation.
CC       {ECO:0000256|ARBA:ARBA00003199}.
CC   -!- SUBCELLULAR LOCATION: Nucleus, Cajal body
CC       {ECO:0000256|ARBA:ARBA00004408}.
CC   -!- SIMILARITY: Belongs to the FAM118 family.
CC       {ECO:0000256|ARBA:ARBA00006491}.
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DR   RefSeq; XP_014070162.1; XM_014214687.1.
DR   AlphaFoldDB; A0A1S3T0R6; -.
DR   STRING; 8030.ENSSSAP00000082779; -.
DR   PaxDb; 8030-ENSSSAP00000082779; -.
DR   Ensembl; ENSSSAT00000200051; ENSSSAP00000161839; ENSSSAG00000067989.
DR   GeneID; 106612962; -.
DR   KEGG; sasa:106612962; -.
DR   OMA; WGKQNEL; -.
DR   OrthoDB; 5318287at2759; -.
DR   Proteomes; UP000087266; Chromosome ssa09.
DR   Bgee; ENSSSAG00000067989; Expressed in sexually immature organism and 15 other cell types or tissues.
DR   GO; GO:0015030; C:Cajal body; IEA:UniProtKB-SubCell.
DR   InterPro; IPR038916; FAM118.
DR   InterPro; IPR039444; SIR2-like.
DR   PANTHER; PTHR28623; PROTEIN FAM118B; 1.
DR   PANTHER; PTHR28623:SF1; PROTEIN FAM118B; 1.
DR   Pfam; PF13289; SIR2_2; 1.
PE   3: Inferred from homology;
KW   Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW   Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW   Reference proteome {ECO:0000313|Proteomes:UP000087266}.
FT   DOMAIN          222..364
FT                   /note="SIR2-like"
FT                   /evidence="ECO:0000259|Pfam:PF13289"
FT   REGION          56..75
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        60..75
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   420 AA;  47108 MW;  887A1474572F4547 CRC64;
     MSIVDCTGFL TRSCKPADVN GSSASKLNIS TDQKSNLELS GSRMASVVAS VVTVKTEKRP
     APADPQDVDS NTKKPRIWEP SMEPSLNLCL PQRKLLPSLK TKRASELVLV IGTGVSSAVA
     PQVPALRSWK GLIQALLDAA NDFDLLEEEE SRRFQKSLKD DKNLVHVAHD LIQKLSPRTG
     NVRSTFFKDC LYEVFDDLEC KMENAGKHLL RSVLQLMESG ALVLTTNFDN LLEIYAAHQG
     SKLESLDLTD EKKVLEWAQG KRSLSVLHIH GVYTNPSGIV LHPAGYQNVL RNTEVMREIQ
     KLYETKSFVF LGCGRTVDDT TFQALFLEAV KHKSDLEHFM LVRREDVGEF KKLRDNMLDK
     GIKVISYGNE YSDLPEYFER LANEICNRDV VTNGWGSPSQ EQETQNGFHP QKCLLQDYSS
//