ID A0A1S3T1E7_SALSA Unreviewed; 908 AA.
AC A0A1S3T1E7;
DT 12-APR-2017, integrated into UniProtKB/TrEMBL.
DT 12-APR-2017, sequence version 1.
DT 27-MAR-2024, entry version 26.
DE SubName: Full=Solute carrier family 12 member 9-like {ECO:0000313|RefSeq:XP_014070411.1};
GN Name=LOC106613052 {ECO:0000313|RefSeq:XP_014070411.1};
OS Salmo salar (Atlantic salmon).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Protacanthopterygii; Salmoniformes;
OC Salmonidae; Salmoninae; Salmo.
OX NCBI_TaxID=8030 {ECO:0000313|Proteomes:UP000087266, ECO:0000313|RefSeq:XP_014070411.1};
RN [1] {ECO:0000313|RefSeq:XP_014070411.1}
RP IDENTIFICATION.
RC TISSUE=Muscle {ECO:0000313|RefSeq:XP_014070411.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the SLC12A transporter family.
CC {ECO:0000256|ARBA:ARBA00010593}.
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DR RefSeq; XP_014070411.1; XM_014214936.1.
DR AlphaFoldDB; A0A1S3T1E7; -.
DR STRING; 8030.ENSSSAP00000032264; -.
DR PaxDb; 8030-ENSSSAP00000032264; -.
DR KEGG; sasa:106613052; -.
DR OrthoDB; 5490251at2759; -.
DR Proteomes; UP000087266; Chromosome ssa09.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0015377; F:chloride:monoatomic cation symporter activity; IEA:InterPro.
DR Gene3D; 1.20.1740.10; Amino acid/polyamine transporter I; 1.
DR InterPro; IPR004841; AA-permease/SLC12A_dom.
DR InterPro; IPR018491; SLC12_C.
DR InterPro; IPR004842; SLC12A_fam.
DR PANTHER; PTHR11827:SF96; SOLUTE CARRIER FAMILY 12 MEMBER 9; 1.
DR PANTHER; PTHR11827; SOLUTE CARRIER FAMILY 12, CATION COTRANSPORTERS; 1.
DR Pfam; PF00324; AA_permease; 1.
DR Pfam; PF03522; SLC12; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000087266};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 52..75
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 87..114
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 135..162
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 182..204
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 211..232
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 284..304
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 325..349
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 369..393
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 414..431
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 437..459
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 471..496
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 57..473
FT /note="Amino acid permease/ SLC12A"
FT /evidence="ECO:0000259|Pfam:PF00324"
FT DOMAIN 560..612
FT /note="SLC12A transporter C-terminal"
FT /evidence="ECO:0000259|Pfam:PF03522"
FT REGION 793..816
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 799..814
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 908 AA; 100063 MW; 313331A6B214B419 CRC64;
MSERTPLLHY RLSTSVNEQS GEHQPCLARE AVEQSPAVSR RKSAHHSRPK KLSTFFGVVI
PTLLSMFSVV VFLRIGFVVG QCGLYQAIAM FLVAYFIISM TVLSVCAIST NGALDAGGAY
YMISRALGPE FGGSLGVMFF LANVCSSALY ILGLVEAIVA TFGLPEDGVS PAGSLQVLPA
GYWWSLLYAT GILLLCLLVC LVGAEIYAKA SFIIFLVVML VLATIFISFF AVRPRTILLP
AAPPIHNSTG PQPPTMANFT GFKLNTLLGN LDADYAVDYT TGTMMSFATV FAVMFNGCTG
IMAGSNMSGD LKNPSYSIPR GTITAVIFTF IIYNLLSLMV ACSCDRILLQ RDYSFLRDIN
VWNPLVTVGV YSSTMSAAMS NLIGASRILY ALARDDLFGT VLSPAKKTSR NGNPWVSVLL
SWFLVQLVLF TGKLNTIASI VTIFFLLVYA AVDLACLALE WASAPNFRYA LIILAIQVRG
WGFSLVSLLS GAYVLLWHTA KSGHYTEKEL HLLFSKSTWQ IMAPGQNVCI DIYVLFLSRS
LSPPSLSDTL PSDPLQCRYD SWLSLVDHLN IKAFVNLTLA DSVRHGVQHL LFISGLGGMR
PNTLVLGFYD DCTPKDKLTD HNLADATVPT QDPEDERPPY HFPALRASID GNGENGKVMG
PQEYVAVIAD AMKMLKNVAL ARYFHQFDRA STISSSPGKG ALYVDVWPVN LLRPDSSSYV
DTCSLFLLQL ACVLNMVRAW RHARLRLFLC VEEGRSLRGS EAKLGQLLKE LRIKANVYTV
PWDQQVALHW QRQGEAGKQR PSHQSRREEE EGLGKMGLFE EEEEGDDDYV NSFPSNATRL
SDEYLSAVNR LILEQARPPP AVRFLYLPRP PADTRRYTAY LRQLDLLTKD LGPTLLIHGV
TPVLTTDL
//
